Strong protective effect of the APOL1 p.N264K variant against G2-associated focal segmental glomerulosclerosis and kidney disease

Autor: Yask Gupta, David J. Friedman, Michelle T. McNulty, Atlas Khan, Brandon Lane, Chen Wang, Juntao Ke, Gina Jin, Benjamin Wooden, Andrea L. Knob, Tze Y. Lim, Gerald B. Appel, Kinsie Huggins, Lili Liu, Adele Mitrotti, Megan C. Stangl, Andrew Bomback, Rik Westland, Monica Bodria, Maddalena Marasa, Ning Shang, David J. Cohen, Russell J. Crew, William Morello, Pietro Canetta, Jai Radhakrishnan, Jeremiah Martino, Qingxue Liu, Wendy K. Chung, Angelica Espinoza, Yuan Luo, Wei-Qi Wei, Qiping Feng, Chunhua Weng, Yilu Fang, Iftikhar J. Kullo, Mohammadreza Naderian, Nita Limdi, Marguerite R. Irvin, Hemant Tiwari, Sumit Mohan, Maya Rao, Geoffrey K. Dube, Ninad S. Chaudhary, Orlando M. Gutiérrez, Suzanne E. Judd, Mary Cushman, Leslie A. Lange, Ethan M. Lange, Daniel L. Bivona, Miguel Verbitsky, Cheryl A. Winkler, Jeffrey B. Kopp, Dominick Santoriello, Ibrahim Batal, Sérgio Veloso Brant Pinheiro, Eduardo Araújo Oliveira, Ana Cristina Simoes e Silva, Isabella Pisani, Enrico Fiaccadori, Fangming Lin, Loreto Gesualdo, Antonio Amoroso, Gian Marco Ghiggeri, Vivette D. D’Agati, Riccardo Magistroni, Eimear E. Kenny, Ruth J. F. Loos, Giovanni Montini, Friedhelm Hildebrandt, Dirk S. Paul, Slavé Petrovski, David B. Goldstein, Matthias Kretzler, Rasheed Gbadegesin, Ali G. Gharavi, Krzysztof Kiryluk, Matthew G. Sampson, Martin R. Pollak, Simone Sanna-Cherchi

Publikováno v: Nature Communications, Vol 14, Iss 1, Pp 1-8 (2023)

Abstract African Americans have a significantly higher risk of developing chronic kidney disease, especially focal segmental glomerulosclerosis -, than European Americans. Two coding variants (G1 and G2) in the APOL1 gene play a major role in this di

Externí odkaz: https://doaj.org/article/9f6233ad88a44f828fd1c0264b712139

Pathology of Calcineurin and Mammalian Target of Rapamycin Inhibitors in Kidney Transplantation

Autor: Rita Leal, Demetra Tsapepas, Russell J. Crew, Geoffrey K. Dube, Lloyd Ratner, Ibrahim Batal

Publikováno v: Kidney International Reports, Vol 3, Iss 2, Pp 281-290 (2018)

The recent evolution in immunosuppression therapy has led to significant improvement in short-term kidney allograft outcomes; however, this progress did not translate into similar improvement in long-term graft survival. The latter, at least in part,

Externí odkaz: https://doaj.org/article/3bd74cc74c434e6b85a4c8642e84b2ed

Disaster Response to the COVID-19 Pandemic for Patients with Kidney Disease in New York City

Autor: Pietro A. Canetta, Irina Y. Baramidze, Krzysztof Kiryluk, Sean Kalloo, Syeda B. Ahmad, Bessie N. Craig, Maya K. Rao, Jason Zheng, Jonathan Barasch, Jane Akomeah, Syed A. Husain, Vaqar H. Shah, Gail Williams, Jordann Lewis, Robin Ferrer, Maria M. Morban, Shayan Shirazian, Andrew S. Bomback, Andrew A. Moses, Meeran Lee, Jacob S. Stevens, Piotr Starakiewicz, Andrew Beenken, Bradley Nelson, Qais Al-Awqati, Allyson R. Medina, Maddalena Marasa, Vanna M. Nicasio, Stacy Piva, Emily Daniel, Iman Azam Ghavami, Karla Mehl, Geoffrey K. Dube, Simone Sanna-Cherchi, Rosemary V. Sampogna, Bruno Lovisi, Hilda Fernandez, Anthony M. Valeri, Maria Alejandra Aponte, David J. Cohen, Jung Soo Kim, Katherine Toma, Kathryn Paget, Hector Alvarado Verduzco, Sumit Mohan, Jai Radhakrishnan, Eric Siddall, Pascale Khairallah, Jordan G. Nestor, Nisha Clement, Denzil Douglas, Heather Morris, Gerald B. Appel, Ali G. Gharavi, Yonatan Peleg, Donald W. Landry, Wooin Ahn, Daisy Mathew, Russell J. Crew, Jae Hyung Chang, Tom Nickolas

Publikováno v: J Am Soc Nephrol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2d72e3af4df63a35bb30fc35206cc11
https://doi.org/10.1681/asn.2020040520

Diagnostic Utility of Exome Sequencing for Kidney Disease

Autor: Hila Milo-Rasouly, Sophia R. Cameron-Christie, Vimla Aggarwal, Carolina Haefliger, Byum Hee Kil, Adam Platt, Brett Copeland, Andrew S. Bomback, Wan Yee Lam, Natalie S Uy, Simone Sanna-Cherchi, Junying Zhang, Rachel Reingold, Zhong Ren, Stacy Piva, Adele Mitrotti, David J. Cohen, Debanjana Chatterjee, Ruth March, Emily E. Groopman, Maddalena Marasa, Drew Bradbury, Sumit Mohan, Michael DiVecchia, David Goldstein, Shumyle Alam, Colin D. Malone, Jordan G. Nestor, Jan Fleckner, Chunhua Weng, Gerald B. Appel, Yifu Li, Priya Krithivasan, Russell J. Crew, Neha Dagaonkar, Olivia Balderes, Karla Mehl, David Fasel, Holly J. Snyder, Maya K. Rao, Joshua Bridgers, Geoffrey K. Dube, Krzysztof Kiryluk, Pietro A. Canetta, Bengt Fellström, Ali G. Gharavi, Jai Radhakrishnan, Wooin Ahn, Caroline Mebane, Slavé Petrovski, Xueru Mu, Sitharthan Kamalakaran

Publikováno v: New England Journal of Medicine. 380:142-151

BACKGROUND: Exome sequencing is emerging as a first-line diagnostic method in some clinical disciplines, but its usefulness has yet to be examined for most constitutional disorders in adults, including chronic kidney disease, which affects more than

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1e8c8b3cbd348e504a27d334077dccd
https://doi.org/10.1056/nejmoa1806891

Febrile neutropenia after kidney transplantation

Autor: Sumit Mohan, Syed A. Husain, David J. Cohen, Marcus R. Pereira, Geoffrey K. Dube, Heather Morris, Russell J. Crew

Publikováno v: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant SurgeonsREFERENCES. 21(10)

Neutropenia is common after kidney transplant. There are few data on febrile neutropenia episodes (FNE) after kidney transplant. We studied FNE in a single-center retrospective cohort of 1682 kidney transplant recipients. Neutropenia (absolute neutro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::165d72f4191b847506407800e45cf004
https://pubmed.ncbi.nlm.nih.gov/34105882