Zobrazeno 1 - 10
of 154
pro vyhledávání: '"A J, CROWLE"'
Publikováno v:
American Review of Respiratory Disease. 146:1448-1451
A recent study in the murine model suggested that a combination of rifampin and pyrazinamide used as preventive therapy might shorten the duration of treatment time. Clinical trials using this combination have been initiated, but significant results
Autor:
George G. Zhanel, Shinjiro Hashimoto, K. Kyriakis, Isola, A.F. Mentis, B. Joly, Atsushi Saito, Yasuaki Osadd, Ross J. Davidson, Arcangelo, A. Quaglietta, Richard Greenberg, Antonio, Kyuichi Matsubayashi, G. Gialdroni Grassi, Mary H. May, S. Betti, K.D. Bremm, Alfred J. Crowle, R. Di Gianfilippo, K.G. Metzger, Martínez Díaz, Gómez Barrio, A. Tsakris, Daryl J. Hoban, Robert H. K. Eng, George S. Douvas, Hishama Saldin, A. Spadano, Sung Kim, P. Accorsi, U. Petersen, J. Rodríguez, A. Piergallini, M. Dell, R. Endermann, R. Cluzel, J. Atienza, Charles E. Cherubin, C. Jallat, Jingoro Shimada, Hussain Qadri, A. Recchia, J.A. Escario, Diane M. Citron, Sharon M. Smith, Kenneth Yen, Ellie J. C. Goldstein, Kumi Yoshida, Osamu Sakai, A. Fietta, C. Mastrangelo, P. Boeri, C. Forestier, A. Iacone, Saleh R. Al-Ballaa, D. Natale, Yoshio Ueno, Kohya Shiba, Lindsay E. Nicolle, N.J. Legakis, Joanne Crampton, L.S. Tzouvelekis, A. Darfeuille-Michaud, C. Ochoa, A. Herrero, Masaki Yoshida, E. Tzelepi, G. Fioritoni, G. Torlontano, M.L. Colombo, C. Merlini
Publikováno v:
Chemotherapy. 38:I-VI
Publikováno v:
Chemotherapy. 38:410-419
Chlorpromazine (CPZ) is one of several phenothiazines known to have antimicrobial properties. It can inhibit mycobacteria, and was reported in the early literature to improve tuberculosis clinically. CPZ was tested here for its ability to inhibit the
Autor:
N Elkins, A J Crowle
Publikováno v:
Infection and Immunity. 58:632-638
Epidemiological, clinical, and histopathological evidence suggests that black people are more susceptible to tuberculosis than are white people. The cellular basis of this putative susceptibility was investigated in vitro by comparing responses of bl
Publikováno v:
Infection and immunity. 60(9)
Patients with AIDS commonly develop disseminated infections with Mycobacterium avium (MA) but not its close relative, M. intracellulare (MI). In non-AIDS patients who have these infections, the two species are about equally distributed. The higher in
Serum from some AIDS patients permits the rapid multiplication of Mycobacterium avium in cultured human macrophages. Serum from human immunodeficiency virus-negative individuals inhibits replication. The characteristics of the serum-induced inhibitio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::825c6f2a88b2b81ea6a211906c7778d2
https://europepmc.org/articles/PMC257634/
https://europepmc.org/articles/PMC257634/
Mycobacterium tuberculosis and Mycobacterium avium multiply in cultured human macrophages (MP) within membrane-enclosed vesicles. These vesicles are generally assumed to be acidic. The evidence most frequently cited for this assumption is that pyrazi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf2c16a0d1971a6589faeb2662f92aa9
https://europepmc.org/articles/PMC257922/
https://europepmc.org/articles/PMC257922/
Autor:
M H May, A J Crowle
Intracellular tubercle bacilli (TB) reside in vacuoles in infected human macrophages (MPs). The relative impotency of streptomycin against TB in MPs and the contrary greatly increased potency of pyrazinamide (PZA) have been attributed to the fact tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e108c9bc7861e750f56ba550cd7595bd
https://europepmc.org/articles/PMC172025/
https://europepmc.org/articles/PMC172025/
Pyrazinamide (PZA) has become an essential component of current 6-month regimens for therapy of tuberculosis. Susceptible strains of tubercle bacilli convert PZA to pyrazinoic acid (POA) through pyrazinamidase (PZase), which resistant strains and Myc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90712bfccd0074fe942a58b8591771e2
https://doi.org/10.5167/uzh-154405
https://doi.org/10.5167/uzh-154405
Autor:
Alfred J. Crowle, Elise J. Ross
Publikováno v:
Journal of leukocyte biology. 47(6)
Vitamin D metabolites have several biologic functions besides the best-known one of controlling mineral metabolism, one of which may be protection against tuberculosis. The chemical structures of the metabolites govern their functions. The most poten