Zobrazeno 1 - 10
of 4 319
pro vyhledávání: '"A J, Armstrong"'
Autor:
Todd P. Knutson, Bin Luo, Anna Kobilka, Jacqueline Lyman, Siyuan Guo, Sarah A. Munro, Yingming Li, Rakesh Heer, Luke Gaughan, Michael J. Morris, Himisha Beltran, Charles J. Ryan, Emmanuel S. Antonarakis, Andrew J. Armstrong, Susan Halabi, Scott M. Dehm
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Circulating tumor DNA (ctDNA) in plasma cell free DNA (cfDNA) of cancer patients is associated with poor prognosis, but is challenging to detect from low plasma volumes. In metastatic castration-resistant prostate cancer (mCRPC), ctDNA assay
Externí odkaz:
https://doaj.org/article/959cb42600c6433490629b1e84221048
Autor:
Reagan M. Barnett, Albert Jang, Sree Lanka, PIngfu Fu, Leslie A. Bucheit, Hani Babiker, Alan Bryce, Haley M. Meyer, Yujin Choi, Casey Moore, Rohan Garje, Xin Gao, Dae Won Kim, Richard Y. Chang, Pat Gulhati, Ryne Ramaker, Rani Bansal, Tian Zhang, A. Oliver Sartor, Andrew J. Armstrong, Mehmet A. Bilen, Pedro Barata
Publikováno v:
Communications Medicine, Vol 4, Iss 1, Pp 1-7 (2024)
Abstract Background Breast and prostate tumors are known to be less responsive to immune checkpoint inhibitors (ICIs). Tissue-based tumor mutation burden (tTMB) has emerged as a predictive biomarker of response to ICIs, including in these “cold tum
Externí odkaz:
https://doaj.org/article/bec170d452674488b50867efdc8a48c0
Publikováno v:
Human-Centric Intelligent Systems, Vol 4, Iss 3, Pp 417-436 (2024)
Abstract As the rise in cancer cases, there is an increasing demand to develop accurate and rapid diagnostic tools for early intervention. Pathologists are looking to augment manual analysis with computer-based evaluation to develop more efficient ca
Externí odkaz:
https://doaj.org/article/a38357d3ddb9431a8dd8eaa0ace7da4a
Autor:
Thomas Nicholson, Amritpal Dhaliwal, Jonathan I. Quinlan, Sophie L. Allen, Felicity R. Williams, Jon Hazeldine, Kirsty C. McGee, Jack Sullivan, Leigh Breen, Ahmed M. Elsharkawy, Matthew J. Armstrong, Simon W. Jones, Carolyn A. Greig, Janet M. Lord
Publikováno v:
Experimental and Molecular Medicine, Vol 56, Iss 7, Pp 1667-1681 (2024)
Abstract Patients with chronic liver disease (CLD) often present with significant frailty, sarcopenia, and impaired immune function. However, the mechanisms driving the development of these age-related phenotypes are not fully understood. To determin
Externí odkaz:
https://doaj.org/article/0915fd3c614042489026aea03cbe9dbe
Autor:
Alice Freer, Felicity R. Williams, Simon Durman, Jennifer Hayden, Matthew J. Armstrong, Palak J. Trivedi
Publikováno v:
JHEP Reports, Vol 6, Iss 12, Pp 101210- (2024)
Background & Aims: Fatigue is a commonly reported symptom of primary biliary cholangitis (PBC). We conducted a single-arm, open-label clinical trial to assess the efficacy of a physiotherapist-led home-based exercise programme (HBEP) in patients with
Externí odkaz:
https://doaj.org/article/3c995bbe9ba94ae3b089e747f5ab2a14
Autor:
Easton N. Wollney, Carma L. Bylund, Noheli Bedenfield, Naomi D. Parker, Mónica Rosselli, Rosie E. Curiel Cid, Marcela Kitaigorodsky, Melissa J. Armstrong
Publikováno v:
PEC Innovation, Vol 4, Iss , Pp 100253- (2024)
Objective: As the number of individuals diagnosed with dementia increases, so does the need to understand the preferences of persons living with dementia (PLWD) and caregivers for how clinicians can deliver a dementia diagnosis effectively, which can
Externí odkaz:
https://doaj.org/article/7ef0279f87114c5cabe3263b5e54fefd
Autor:
William Bernal, Rhiannon Taylor, Ian A. Rowe, Abhishek Chauhan, Matthew J. Armstrong, Michael E.D. Allison, Gwilym Webb, Tasneem Pirani, Joanna Moore, Laura Burke, Steven Masson, David Cressy, Brian J. Hogan, Rachel Westbrook, Rajiv Jalan, Kenneth J. Simpson, John Isaac, Douglas Thorburn
Publikováno v:
The Lancet Regional Health. Europe, Vol 46, Iss , Pp 101067- (2024)
Summary: Background: Acute on Chronic Liver Failure (ACLF) complicates chronic liver disease (CLD) combining rapidly progressive hepatic with extra-hepatic multiple organ failure and high short-term mortality. Effective therapeutic options are very l
Externí odkaz:
https://doaj.org/article/adaca2eb8cbe453daf3287fe0f7ea985
Autor:
K. M. Benzies, D. B. Nicholas, K. A. Hayden, T. Barnas, A. de Koning, A. Bharwani, J. Armstrong, J. Day
Publikováno v:
Humanities & Social Sciences Communications, Vol 11, Iss 1, Pp 1-11 (2024)
Abstract Education, research, and contribution to society through innovation are the three missions of post-secondary educational institutions. There is a gap in understanding the concept of social innovation for post-second educational institutions.
Externí odkaz:
https://doaj.org/article/5b16859bc9e94e51a93411f5cf7f2154
Autor:
Gemma Slinn, Peter Brocklehurst, Clare Melikian, Chiemelie Ngonadi, Yongzhong Sun, Samir Mehta, Francesca Gowing, Alice Freer, Wendy Osborne, Karen Rockell, Nicholas Adams, Sukhwant Sehmi, Matthew J. Armstrong, Sharon Augustt, Shahida Begum, Liam Botfield, Dawn Brant, Emily Clibbens, Nigel Cope, Joan L. Duda, Sally A.M. Fenton, David J. Garside, Ashlea Hargreaves, William Leach, Daniel S. Martin, Don Milliken, Sonia Murray, Christian Price, Felicity R. Williams, Shu Xiaoyi
Publikováno v:
BMJ Open Gastroenterology, Vol 11, Iss 1 (2024)
Introduction Physical frailty is associated with increased mortality and poor quality of life (QoL) before and after liver transplantation (LT). Evidence is lacking on how to tailor exercise and behavioural techniques in this patient population.Metho
Externí odkaz:
https://doaj.org/article/c68f388f3a3a43c3a0b07be946e5c252
Autor:
Breton M. Asken, Jesse C. DeSimone, Wei‐En Wang, Karen N. McFarland, Franchesca Arias, Shellie‐Anne Levy, Jacob Fiala, Idaly Velez‐Uribe, Robin P. Mayrand, Luana Okino Sawada, Christian Freytes, Michael Adeyosoye, Warren W. Barker, Elizabeth A. Crocco, Steven T. DeKosky, Malek Adjouadi, Monica Rosselli, Michael Marsiske, Melissa J. Armstrong, Glenn E. Smith, Rosie Curiel Cid, David A. Loewenstein, David E. Vaillancourt, Ranjan Duara
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 16, Iss 3, Pp n/a-n/a (2024)
Abstract INTRODUCTION Commercially available plasma p‐tau217 biomarker tests are not well studied in ethnically diverse samples. METHODS We evaluated associations between ALZPath plasma p‐tau217 and amyloid‐beta positron emission tomography (A
Externí odkaz:
https://doaj.org/article/6a96aa6ce47742c6a1d4d3c40f5209d4