Zobrazeno 1 - 10
of 24
pro vyhledávání: '"A I Lauerma"'
Autor:
Minna Anthoni, Guoying Wang, Marina S. Leino, Antti I. Lauerma, Harri T. Alenius, Henrik J. Wolff
Publikováno v:
International Journal of Biological Sciences, Vol 3, Iss 7, Pp 477-485 (2007)
This study investigates the role of Smad3 signalling for the T-helper2 (Th2) cytokine homeostasis in normal lungs and in a mouse model of asthma. We used mice deficient for Smad3, a central part of the major signal transduction pathway for TGF-β and
Externí odkaz:
https://doaj.org/article/2d5032d70ccf4ad4b814f6df97976f6c
Publikováno v:
Journal of Applied Toxicology. 17:357-360
The respiratory allergen trimellitic anhydride (TMA) has been shown to induce IgE production and immediate ear swelling in mice sensitized to it. We studied whether TMA sensitivity could be used as an animal model for immunological contact urticaria.
Publikováno v:
Skin Pharmacology and Physiology. 10:230-234
Cyclosporin A (CsA) is efficacious in many dermatoses as an oral but not as a topical form, while tacrolimus (FK506) has been shown to be effective in both forms. As inadequate skin absorption has been proposed as the reason for inefficacy of topical
Publikováno v:
British Journal of Dermatology. 134:904-909
Cis-urocanic acid (cUCA) has been suggested as a mediator of impairment of contact hypersensitivity induction by ultraviolet B (UVB) irradiation. We ascertained whether topical cUCA influences local lymph node activation during induction of contact h
Publikováno v:
Archives of Dermatological Research. 286:337-340
Topical FK506 has recently been shown to have an anti-inflammatory effect in vivo in humans. In this study its effects in contact dermatitis were studied in the guinea pig model. Topical FK506 suppressed both irritant and allergic patch-test reaction
Autor:
A I Lauerma, Howard I. Maibach
Publikováno v:
Dermatology. 188:173-176
Cyclosporine A (CsA) is an immunosuppressant that is efficacious in several inflammatory skin disorders. Its use is, however, limited due to systemic side-effects. Topical forms of CsA have been tried but they do not seem to be effective presumably d
Publikováno v:
Contact Dermatitis. 29:1-5
Contact hypersensitivity may be diagnosed with patch testing or intradermal testing. Although these methods have been used earlier in parallel, patch testing has gradually become the only method in routine diagnosis of contact allergy. Recent finding
Autor:
Howard I. Maibach, A I Lauerma
Publikováno v:
Dermatotoxicology, Sixth Edition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e6304dbcf24e1335d78a9acd51b419b
https://doi.org/10.1201/9780203426272.ch49
https://doi.org/10.1201/9780203426272.ch49
Autor:
L. Kanerva, A. I. Lauerma
Publikováno v:
European Handbook of Dermatological Treatments ISBN: 9783642056574
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::41371e96d5224b7cd05933f7a40b0ade
https://doi.org/10.1007/978-3-662-07131-1_17
https://doi.org/10.1007/978-3-662-07131-1_17
Autor:
A I, Lauerma
Publikováno v:
Contact dermatitis. 44(1)