Zobrazeno 1 - 10
of 358
pro vyhledávání: '"A I Adler"'
Publikováno v:
Endocrinology, Diabetes & Metabolism Case Reports, Vol 1, Iss 1, Pp 1-4 (2024)
Kabuki syndrome is a genetic disorder characterised by distinctive facial features, developmental delays, and multisystem congenital anomalies. Endocrine complications such as premature thelarche and short stature are common, whereas disorders of gly
Externí odkaz:
https://doaj.org/article/0afdb41d40a440929834de373de4259d
Autor:
Naveed Sattar, Sofia Dias, Sarah Wild, Laurie A Tomlinson, David McAllister, Amanda I Adler, Nicky Welton, Lili Wei, Katherine Hughes, Peter Hanlon, Elaine Butterly, Jim Lewsey, John Petrie, Robert Lindsay, Saleh A M Almazam, Khalid Alsallumi, Luke A K Blackbourn, Stuart McGurnaghan, David Phillippo
Publikováno v:
BMJ Open, Vol 12, Iss 10 (2022)
Introduction Participants in randomised controlled trials (trials) are generally younger and healthier than many individuals encountered in clinical practice. Consequently, the applicability of trial findings is often uncertain. To address this, resu
Externí odkaz:
https://doaj.org/article/946d5f6599ce403f8514b5c0facf5297
Autor:
Haoxiang Yang, Özge Sürer, Daniel Duque, David P. Morton, Bismark Singh, Spencer J. Fox, Remy Pasco, Kelly Pierce, Paul Rathouz, Victoria Valencia, Zhanwei Du, Michael Pignone, Mark E. Escott, Stephen I. Adler, S. Claiborne Johnston, Lauren Ancel Meyers
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-7 (2021)
Selection of COVID-19 mitigation measures requires balancing health outcomes with economic impacts. Here, the authors derive a system to set triggers for increasing mitigation measures to preserve healthcare capacity, and describe how it has been use
Externí odkaz:
https://doaj.org/article/1e624f2e40294b17968d4437f8a042fa
Autor:
Kevin A. Guttenplan, Maya K. Weigel, Drew I. Adler, Julien Couthouis, Shane A. Liddelow, Aaron D. Gitler, Ben A. Barres
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Astrocyte activation may contribute to neurodegenerative disease. Here the authors show that the combined knockout of three factors known to promote astrogliosis, IL-1α, TNFα and C1qa, leads to improved survival in the SOD1 G93A mouse model of ALS.
Externí odkaz:
https://doaj.org/article/04bb3c77114848c1a13fa651c535c520
Autor:
Kamlesh Khunti, Samantha Wilkinson, Liam Smeeth, Laurie A Tomlinson, Amanda I Adler, Ian J Douglas, Andrew Briggs, Richard Grieve, Stephen O’neill, Richard J Silverwood, Paul Charlton, Patrick Bidulka, Anirban Basu
Publikováno v:
BMJ Open, Vol 11, Iss 9 (2021)
Introduction For people with type 2 diabetes mellitus (T2DM) who require an antidiabetic drug as an add-on to metformin, there is controversy about whether newer drug classes such as dipeptidyl peptidase-4 inhibitors (DPP4i) or sodium-glucose co-tran
Externí odkaz:
https://doaj.org/article/33fdba588b1043e1a5ec01b6dca7066c
Autor:
Patrick Bidulka, Rohini Mathur, David G. Lugo‐Palacios, Stephen O'Neill, Anirban Basu, Richard J. Silverwood, Paul Charlton, Andrew Briggs, Liam Smeeth, Amanda I. Adler, Ian J. Douglas, Kamlesh Khunti, Richard Grieve
Publikováno v:
Diabetes, Obesity and Metabolism. 25:282-292
To assess any disparities in the initiation of second-line antidiabetic treatments prescribed among people with type 2 diabetes mellitus (T2DM) in England according to ethnicity and social deprivation level.This cross-sectional study used linked prim
Autor:
Martin R. Cowie, Biykem Bozkurt, Javed Butler, Andrew Briggs, Maria Kubin, Adrian Jonas, Amanda I. Adler, Bray Patrick-Lake, Faiez Zannad
Publikováno v:
International Journal of Cardiology
International Journal of Cardiology, 2022, 365, pp.61-68. ⟨10.1016/j.ijcard.2022.07.020⟩
International Journal of Cardiology, 2022, 365, pp.61-68. ⟨10.1016/j.ijcard.2022.07.020⟩
International audience; Regulatory approvals of, and subsequent access to, innovative cardiovascular medications have declined. How much of this decline relates to the final step of gaining reimbursement for new treatments is unknown. Payers and heal
Autor:
Anne Lübbeke, Alan J. Silman, Daniel Prieto-Alhambra, Amanda I. Adler, Christophe Barea, Andrew J. Carr
Publikováno v:
BMC Musculoskeletal Disorders, Vol 18, Iss 1, Pp 1-7 (2017)
Abstract Background The serious adverse events associated with metal on metal hip replacements have highlighted the importance of improving methods for monitoring surgical implants. The new European Union (EU) device regulation will enforce post-mark
Externí odkaz:
https://doaj.org/article/716a5381685b4965ac99747179743e29
Autor:
R. Coraza, I. Adler, K. Granholm, R. Rampariag, H. Baron, T.-C.M. Rosenberg, H. Bien, V. Chang, M.R. Al Ajam, I. Chernyavskiy, S. Bates, C. Luhrs, J.J. Tsay
Publikováno v:
C58. HEALTH SERVICES RESEARCH IN DIVERSE SETTINGS.
Autor:
M. Angelyn Bethel, Harald Sourij, Susanna R. Stevens, Karen Hannan, Yuliya Lokhnygina, Amanda I. Adler, Eric D. Peterson, Rury R. Holman, Renato D. Lopes
Publikováno v:
Cardiovascular Diabetology. 22
Background Estimating cardiovascular (CV) event accrual is important for outcome trial planning. Limited data exist describing event accrual patterns in patients with type 2 diabetes (T2D). We compared apparent CV event accrual patterns with true eve