Zobrazeno 1 - 10
of 32
pro vyhledávání: '"A I, Luĭk"'
Publikováno v:
Bioorganicheskaia khimiia. 27(4)
A volume learning algorithm for artificial neural networks was developed to quantitatively describe the three-dimensional structure-activity relationships using as an example N-benzylpiperidine derivatives. The new algorithm combines two types of neu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dc31f93f8e4870f9765c0935f4379717
https://pubmed.ncbi.nlm.nih.gov/11558265
https://pubmed.ncbi.nlm.nih.gov/11558265
Publikováno v:
Voprosy meditsinskoi khimii. 45(6)
Using experimental transcription model in vitro, and method of electron-topological calculations the elements of pharmacological and structural community have been found in the groups of physiologically active compounds (PAC), blocking and activating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::58d596a4df59da0b95fa18ab1e4657d9
https://pubmed.ncbi.nlm.nih.gov/10761218
https://pubmed.ncbi.nlm.nih.gov/10761218
Publikováno v:
Ukrains'kyi biokhimichnyi zhurnal (1999 ). 71(3)
The influence of physical and chemical properties of some sites of transmembrane receptor domains on the receptors ability to interact with nonspecific antagonists was investigated mathematically. The properties of sites located in 3rd and 7th transm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::875c6e4fce06c330910e232a1590783b
https://pubmed.ncbi.nlm.nih.gov/10609327
https://pubmed.ncbi.nlm.nih.gov/10609327
Publikováno v:
Ukrainskii biokhimicheskii zhurnal (1. 70(4)
The influence of the tricyclic antidepressants imipramine and ftoracizin on platelet aggregation and smooth muscle contractility was investigated in comparison with action of known smooth muscle relaxant and platelet aggregation inhibitor, papaverine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dd24057db9ee61f8200f39135707fd61
https://pubmed.ncbi.nlm.nih.gov/9848209
https://pubmed.ncbi.nlm.nih.gov/9848209
Publikováno v:
Ukrainskii biokhimicheskii zhurnal (1. 69(1)
The character of structural rearrangements in leukocyte membranes affected by 5-lipoxygenase inhibitors: quercetin and linoleic acid hydroxamate, has been investigated. Quercetin has been shown to induce the translocation of tryptophanyls and tyrosyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a024d0bdd0990620e24ae0a403ed47d9
https://pubmed.ncbi.nlm.nih.gov/9454378
https://pubmed.ncbi.nlm.nih.gov/9454378
Publikováno v:
Klinicheskaia laboratornaia diagnostika. (4)
Effects of some drugs on different levels of phagocytic activity of polymorphonuclear leukocytes (PMNL) of human peripheral blood were studied in vitro. The drugs were found to regulate the phagocytic activity of PMNL. This effect depended on the ini
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::68ca5a2d593b1c2f6374715981dde3eb
https://pubmed.ncbi.nlm.nih.gov/8963554
https://pubmed.ncbi.nlm.nih.gov/8963554
Publikováno v:
Klinicheskaia laboratornaia diagnostika. (2)
Study on the effects of some drugs on the results of passive hemagglutination test used for the detection of antitetanus antibodies in the blood serum showed that some drugs had a pronounced dose-dependent effect on antibody titers in experiments in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7fa035664668fc899a576fcdd16cf28f
https://pubmed.ncbi.nlm.nih.gov/8680776
https://pubmed.ncbi.nlm.nih.gov/8680776
Publikováno v:
Ukrainskii biokhimicheskii zhurnal (1. 68(1)
The influence of some drugs on E-rosette formation by lymphocytes and on electrophoretic mobility of neutrophilic leukocytes has been studied. It has been found, that the character of drugs influence coincides with common directivity of their action
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::76feee0860a6ac8be7919600f17a13df
https://pubmed.ncbi.nlm.nih.gov/8755108
https://pubmed.ncbi.nlm.nih.gov/8755108
Publikováno v:
Bioorganicheskaia khimiia. 21(10)
Based on a set of compounds possessing hypolipidemic activity, it was demonstrated that evolutionary algorithms can be successfully used to compile an informative set of molecular parameters. The parameter sets selected using the method of potential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::af5adec043ae6ad23e47c96e1c07928c
https://pubmed.ncbi.nlm.nih.gov/8573213
https://pubmed.ncbi.nlm.nih.gov/8573213
Publikováno v:
Ukrainskii biokhimicheskii zhurnal (1. 65(3)
The mobility of the rat polymorphonuclear leukocytes (PMNL) has been studied. It was shown, that it is greatly determined by the balance of adenylate cyclase (AdC) and Ca-polyphosphoinositide (Ca-PPI) cell signalling systems. Various compounds whose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f76f3fe502a6fefbda5b428a418e0023
https://pubmed.ncbi.nlm.nih.gov/8291141
https://pubmed.ncbi.nlm.nih.gov/8291141