Zobrazeno 1 - 10
of 622
pro vyhledávání: '"A I, Levey"'
Autor:
Qi Guo, Lingyan Ping, Eric B. Dammer, Duc M. Duong, Luming Yin, Kaiming Xu, Anantharaman Shantaraman, Edward J. Fox, Todd E Golde, Erik C.B. Johnson, Blaine R. Roberts, James J. Lah, Allan I. Levey, Nicholas T. Seyfried
Publikováno v:
Molecular Neurodegeneration, Vol 19, Iss 1, Pp 1-30 (2024)
Abstract Introduction Heparin binding proteins (HBPs) with roles in extracellular matrix assembly are strongly correlated to β-amyloid (Aβ) and tau pathology in Alzheimer’s disease (AD) brain and cerebrospinal fluid (CSF). However, it remains cha
Externí odkaz:
https://doaj.org/article/45c6f5f8193444e2b5dcf0ca69a39efd
Autor:
Anantharaman Shantaraman, Eric B. Dammer, Obiadada Ugochukwu, Duc M. Duong, Luming Yin, E. Kathleen Carter, Marla Gearing, Alice Chen-Plotkin, Edward B. Lee, John Q. Trojanowski, David A. Bennett, James J. Lah, Allan I. Levey, Nicholas T. Seyfried, Lenora Higginbotham
Publikováno v:
Molecular Neurodegeneration, Vol 19, Iss 1, Pp 1-24 (2024)
Abstract Lewy body dementia (LBD), a class of disorders comprising Parkinson’s disease dementia (PDD) and dementia with Lewy bodies (DLB), features substantial clinical and pathological overlap with Alzheimer’s disease (AD). The identification of
Externí odkaz:
https://doaj.org/article/7ae7acdfdb7b4c38ba5851ba50f50b73
Autor:
Yuhong Du, Dongxue Wang, Vittorio L. Katis, Elizabeth L. Zoeller, Min Qui, Allan I. Levey, Opher Gileadi, Haian Fu
Publikováno v:
SLAS Discovery, Vol 29, Iss 6, Pp 100177- (2024)
The spleen tyrosine kinase (SYK) and high affinity immunoglobulin epsilon receptor subunit gamma (FCER1G) interaction has a major role in the normal innate and adaptive immune responses, but dysregulation of this interaction is implicated in several
Externí odkaz:
https://doaj.org/article/d8073c541d1c4808baf8ed2a88d5e137
Autor:
Richard A Kahn, Harvinder Virk, Carl Laflamme, Douglas W Houston, Nicole K Polinski, Rob Meijers, Allan I Levey, Clifford B Saper, Timothy M Errington, Rachel E Turn, Anita Bandrowski, James S Trimmer, Meghan Rego, Leonard P Freedman, Fortunato Ferrara, Andrew RM Bradbury, Hannah Cable, Skye Longworth
Publikováno v:
eLife, Vol 13 (2024)
Antibodies are used in many areas of biomedical and clinical research, but many of these antibodies have not been adequately characterized, which casts doubt on the results reported in many scientific papers. This problem is compounded by a lack of s
Externí odkaz:
https://doaj.org/article/0b65acdfb7aa48e3af7059256f37ae20
Autor:
McGregor Joyner, Sheng-Hsiou Hsu, Stephanie Martin, Jennifer Dwyer, Denise Fay Chen, Reza Sameni, Samuel H. Waters, Konstantin Borodin, Gari D. Clifford, Allan I. Levey, John Hixson, Daniel Winkel, Jonathan Berent
Publikováno v:
Bioelectronic Medicine, Vol 10, Iss 1, Pp 1-15 (2024)
Abstract Background Seizure detection is challenging outside the clinical environment due to the lack of comfortable, reliable, and practical long-term neurophysiological monitoring devices. We developed a novel, discreet, unobstructive in-ear sensin
Externí odkaz:
https://doaj.org/article/4a43a9bf6faa49cba4a27b9dae90dda7
Autor:
Anantharaman Shantaraman, Eric B. Dammer, Obiadada Ugochukwu, Duc M. Duong, Luming Yin, E. Kathleen Carter, Marla Gearing, Alice Chen-Plotkin, Edward B. Lee, John Q. Trojanowski, David A. Bennett, James J. Lah, Allan I. Levey, Nicholas T. Seyfried, Lenora Higginbotham
Publikováno v:
Molecular Neurodegeneration, Vol 19, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/801efc043f6b4cd1b3e3be375e9c13aa
Autor:
Stephanie Doering, Austin McCullough, Brian A. Gordon, Charles D. Chen, Nicole McKay, Diana Hobbs, Sarah Keefe, Shaney Flores, Jalen Scott, Hunter Smith, Stephen Jarman, Kelley Jackson, Russ C. Hornbeck, Beau M. Ances, Chengjie Xiong, Andrew J. Aschenbrenner, Jason Hassenstab, Carlos Cruchaga, Alisha Daniels, Randall J. Bateman, John C. Morris, Tammie L.S. Benzinger, James M. Noble, Gregory S. Day, Neill R. Graff-Radford, Jonathan Voglein, Johannes Levin, Ricardo F. Allegri, Patricio Chrem Mendez, Ezequiel Surace, Sarah B. Berman, Snezana Ikonomovic, Neelesh K. Nadkarni, Francisco Lopera, Laura Ramirez, David Aguillon, Yudy Leon, Claudia Ramos, Diana Alzate, Ana Baena, Natalia Londono, Sonia Moreno, Mathias Jucker, Christoph Laske, Elke Kuder-Buletta, Susanne Graber-Sultan, Oliver Preische, Anna Hofmann, Takeshi Ikeuchi, Kensaku Kasuga, Yoshiki Niimi, Kenji Ishii, Michio Senda, Raquel Sanchez-Valle, Pedro Rosa-Neto, Nick C. Fox, Dave Cash, Jae-Hong Lee, Jee Hoon Roh, Stephen Salloway, Meghan C. Riddle, William Menard, Courtney Bodge, Mustafa Surti, Leonel Tadao Takada, Martin Farlow, Jasmeer P. Chhatwal, V.J. Sanchez-Gonzalez, Maribel Orozco-Barajas, Alison M. Goate, Alan E. Renton, Bianca T. Esposito, Celeste M. Karch, Jacob Marsh, Victoria Fernanadez, Anne M. Fagan, Gina Jerome, Elizabeth Herries, Jorge Llibre-Guerra, Allan I. Levey, Erik C.B. Johnson, Nicholas T. Seyfried, Peter R. Schofield, William S. Brooks, Jacob A. Bechara, Randall Bateman, Eric McDade, Richard J. Perrin, Erin E. Franklin, Tammie Benzinger, Allison Chen, Charles Chen, Nelly Friedrichsen, Brian Gordon, Nancy Hantler, Russ Hornbeck, Steve Jarman, Deborah Koudelis, Parinaz Massoumzadeh, Joyce Nicklaus, Christine Pulizos, Qing Wang, Sheetal Mishall, Edita Sabaredzovic, Emily Deng, Madison Candela, Peter Wang, Xiong Xu, Yan Li, Emily Gremminger, Yinjiao Ma, Ryan Bui, Ruijin Lu, Ralph Martins, Ana Luisa Sosa Ortiz, Laura Courtney, Hiroshi Mori, Charlene Supnet-Bell, Jinbin Xu, John Ringman, Nicolas Barthelemy, John Morris, Jennifer Smith
Publikováno v:
EBioMedicine, Vol 103, Iss , Pp 105080- (2024)
Summary: Background: Neuroimaging studies often quantify tau burden in standardized brain regions to assess Alzheimer disease (AD) progression. However, this method ignores another key biological process in which tau spreads to additional brain regio
Externí odkaz:
https://doaj.org/article/0b7b8db8958a47c9b99946f7b5107ddb
Autor:
Carl Laflamme, Allan I. Levey, S. J. Sukoff Rizzo, Riham Ayoubi, Sean-Paul G. Williams, Haian Fu, Ranjita Betarbet, Elizabeth Zoeller, Suzanne Doolen
Publikováno v:
F1000Research, Vol 12 (2024)
Background A major goal of the Target Enablement to Accelerate Therapy Development for Alzheimer’s disease (TREAT-AD) program is to develop and identify high-quality tools to test target or mechanistic hypotheses. As part of this initiative, it is
Externí odkaz:
https://doaj.org/article/96d1e51f90f64bbbbbbbaf6c13b8cfc5
Autor:
Kamil Borkowski, Nicholas T. Seyfried, Matthias Arnold, James J. Lah, Allan I. Levey, Chadwick M. Hales, Eric B. Dammer, Colette Blach, Gregory Louie, Rima Kaddurah-Daouk, John W. Newman
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Integration of the omics data, including metabolomics and proteomics, provides a unique opportunity to search for new associations within metabolic disorders, including Alzheimer’s disease. Using metabolomics, we have previously profiled o
Externí odkaz:
https://doaj.org/article/8bf68a11806b4e5a948a71379d7cd203
Autor:
Erica S. Modeste, Lingyan Ping, Caroline M. Watson, Duc M. Duong, Eric B. Dammer, Erik C. B. Johnson, Blaine R. Roberts, James J. Lah, Allan I. Levey, Nicholas T. Seyfried
Publikováno v:
Molecular Neurodegeneration, Vol 18, Iss 1, Pp 1-19 (2023)
Abstract Background Despite being twice as likely to get Alzheimer’s disease (AD), African Americans have been grossly underrepresented in AD research. While emerging evidence indicates that African Americans with AD have lower cerebrospinal fluid
Externí odkaz:
https://doaj.org/article/7b366553a40942d589b546c51e93941a