Zobrazeno 1 - 10
of 51
pro vyhledávání: '"A I, Garbe"'
Autor:
Sebastian Dohnke, Stephanie Moehser, Alexey Surnov, Thomas Kurth, Rolf Jessberger, Karsten Kretschmer, Annette I. Garbe
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
In T cells, processes such as migration and immunological synapse formation are accompanied by the dynamic reorganization of the actin cytoskeleton, which has been suggested to be mediated by regulators of RhoGTPases and by F-actin bundlers. SWAP-70
Externí odkaz:
https://doaj.org/article/a04c09087b1344e5a827e4d3f0519357
Autor:
Luise Fischer, Caroline Herkner, Reni Kitte, Sebastian Dohnke, Julia Riewaldt, Karsten Kretschmer, Annette I. Garbe
Publikováno v:
Frontiers in Endocrinology, Vol 10 (2019)
The bone represents surprisingly dynamic structures that are subject to constant remodeling by the concerted action of bone-forming osteoblasts and bone-resorbing osteoclasts - two cell subsets of distinct developmental origin that are key in maintai
Externí odkaz:
https://doaj.org/article/50f07743c8a64dd99f2c040fe1da061e
Autor:
Anne Roscher, Tomoka Hasegawa, Sebastian Dohnke, Carlos Ocaña-Morgner, Norio Amizuka, Rolf Jessberger, Annette I. Garbe
Publikováno v:
Bone Reports, Vol 5, Iss , Pp 214-221 (2016)
Osteoclasts are bone resorbing cells acting as key mediators of bone disorders. Upon adhesion to bone, osteoclasts polarize and reorganize their cytoskeleton to generate a ring-like F-actin-rich structure, the sealing zone, wherein the osteoclast's r
Externí odkaz:
https://doaj.org/article/96fbb2e8d3d34acc9dc8fdddd60b3b14
Autor:
Tim F. Greten, Firouzeh Korangy, Michael P. Manns, Roland M. Schmid, Jan Buer, Astrid M. Westendorf, Florian R. Greten, Reinhard von Wasielewski, Jaba Gamrekelashvili, Benjamin Vermeer, Annette I. Garbe
Treatment options for pancreatic cancer are limited and often ineffective. Immunotherapeutic approaches are one possible option that needs to be evaluated in appropriate animal models. The aim of the present study was to analyze tumor-specific immune
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::718dd25e86f719dc58cc2f65c7defe38
https://doi.org/10.1158/0008-5472.c.6494724
https://doi.org/10.1158/0008-5472.c.6494724
Autor:
Tim F. Greten, Firouzeh Korangy, Michael P. Manns, Roland M. Schmid, Jan Buer, Astrid M. Westendorf, Florian R. Greten, Reinhard von Wasielewski, Jaba Gamrekelashvili, Benjamin Vermeer, Annette I. Garbe
Supplementary Figure 1 and Table S2 from Genetically Induced Pancreatic Adenocarcinoma Is Highly Immunogenic and Causes Spontaneous Tumor-Specific Immune Responses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6036bb95a5dd01fa80787ac4bd34f240
https://doi.org/10.1158/0008-5472.22365483
https://doi.org/10.1158/0008-5472.22365483
Autor:
Anne-Margarete Brennecke, Sandra Düber, Bishnudeo Roy, Irene Thomsen, Annette I. Garbe, Frank Klawonn, Oliver Pabst, Karsten Kretschmer, Siegfried Weiss
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
We employed the B-Indu-Rag1 model in which the coding exon of recombination-activating gene 1 (Rag1) is inactivated by inversion. It is flanked by inverted loxP sites. Accordingly, B cell development is stopped at the pro/pre B-I cell precursor stage
Externí odkaz:
https://doaj.org/article/226bd695a41a43b0836860a7b1f1963f
Autor:
Kristin Freudenberg, Nadja Lindner, Sebastian Dohnke, Annette I. Garbe, Sonja Schallenberg, Karsten Kretschmer
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Under physiological conditions, CD4+ regulatory T (Treg) cells expressing the transcription factor Foxp3 are generated in the thymus [thymus-derived Foxp3+ Treg (tTregs) cells] and extrathymically at peripheral sites [peripherally induced Foxp3+ Treg
Externí odkaz:
https://doaj.org/article/dd51aea59911405da1134c0a18b8bd86
Autor:
Tatsiana Ripich, Carlos Andrés Chacón-Martínez, Luise Fischer, Alessandra Pernis, Nadine Kiessling, Annette I Garbe, Rolf Jessberger
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0161060 (2016)
SWAP-70 and DEF6, two proteins that feature similar domain and motif arrangements, are mainly known for their functions in differentiated hematopoietic cells. Both proteins interact with and regulate RhoGTPases and F-actin dynamics, yet their role in
Externí odkaz:
https://doaj.org/article/d97e3c5e9502409a820664ebd3a5364e
Autor:
Sebastian, Dohnke, Stephanie, Moehser, Alexey, Surnov, Thomas, Kurth, Rolf, Jessberger, Karsten, Kretschmer, Annette I, Garbe
Publikováno v:
Frontiers in immunology. 13
In T cells, processes such as migration and immunological synapse formation are accompanied by the dynamic reorganization of the actin cytoskeleton, which has been suggested to be mediated by regulators of RhoGTPases and by F-actin bundlers. SWAP-70
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1134a877eaf7393902bb19165f284c45
https://pubmed.ncbi.nlm.nih.gov/35359955
https://pubmed.ncbi.nlm.nih.gov/35359955
Autor:
Lorenz C. Hofbauer, Sylvia Thiele, Christof Niehrs, Martina Rauner, Ulrike Baschant, Juliane Colditz, Annette I. Garbe
Publikováno v:
Journal of Bone and Mineral Research. 34:1314-1323
Dickkopf-1 (Dkk1) is a negative regulator of bone formation and bone mass and is deregulated in bone loss induced by arthritis and glucocorticoid (GC) exposure. However, the role of Dkk1 in these pathological processes is still unknown. Here, we used
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72e99a84f7b12d78a437eadd7b47a815
https://doi.org/10.1002/jbmr.3702
https://doi.org/10.1002/jbmr.3702