Zobrazeno 1 - 10
of 571
pro vyhledávání: '"A I, GOODMAN"'
Autor:
Catherine Bresee, Michael I. Lewis, Robert I Goodman, Tamana Kaderi, Sara Ghandehari, Divya Narayanan, Josephine Hwang, Heli Ghandehari, Victor F. Tapson, Samuel H. Pepkowitz, Yuri Matusov, James Mirocha, Stephanie H Chang, Donald G. Stein
Publikováno v:
Chest. 160:74-84
Background Severity of illness in COVID-19 is consistently lower in women. A focus on sex as a biological factor may suggest a potential therapeutic intervention for this disease. We assessed whether adding progesterone to standard of care (SOC) woul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82be92796c1691ba231fc69d9436dfde
https://doi.org/10.1016/j.chest.2021.02.024
https://doi.org/10.1016/j.chest.2021.02.024
Autor:
Stephen I. Goodman
Publikováno v:
Physician's Guide to the Diagnosis, Treatment, and Follow-Up of Inherited Metabolic Diseases ISBN: 9783030677268
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28f2b7725f034fa92cdca70446e1d562
https://doi.org/10.1007/978-3-030-67727-5_71
https://doi.org/10.1007/978-3-030-67727-5_71
Autor:
Valeska Lizzi Lagranha, Ursula Matte, Talita Giacomet de Carvalho, Bianca Seminotti, Carolina Coffi Pereira, David M Koeller, Michael Woontner, Stephen I Goodman, Diogo Onofre Gomes de Souza, Moacir Wajner
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e90477 (2014)
We determined mRNA expression of the ionotropic glutamate receptors NMDA (NR1, NR2A and NR2B subunits), AMPA (GluR2 subunit) and kainate (GluR6 subunit), as well as of the glutamate transporters GLAST and GLT1 in cerebral cortex and striatum of wild
Externí odkaz:
https://doaj.org/article/a9b5c58ab51645b29375a4783bc432de
Autor:
James E. Trosko, Carr J. Smith, C. Glenn Begley, Thomas A. Perfetti, Sir Colin Berry, Jay I. Goodman, Judy A. King, A. Wallace Hayes, Anthony Dayan
Publikováno v:
Archives of Toxicology.
The International Agency for Research on Cancer (IARC) has recently proposed employing “ten key characteristics of human carcinogens” (TKCs) to determine the potential of agents for harmful effects. The TKCs seem likely to confuse the unsatisfact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b30760626e4c2c117c09af2f84684925
https://doi.org/10.1007/s00204-021-03109-w
https://doi.org/10.1007/s00204-021-03109-w
Autor:
Carr J, Smith, Thomas A, Perfetti, A Wallace, Hayes, Sir Colin, Berry, James E, Trosko, Judy A, King, Jay I, Goodman, C Glenn, Begley, Anthony, Dayan
Publikováno v:
Archives of toxicology. 95(8)
The International Agency for Research on Cancer (IARC) has recently proposed employing "ten key characteristics of human carcinogens" (TKCs) to determine the potential of agents for harmful effects. The TKCs seem likely to confuse the unsatisfactory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cb98ed16a3971023172e7b356189db58
https://pubmed.ncbi.nlm.nih.gov/34148101
https://pubmed.ncbi.nlm.nih.gov/34148101
Autor:
Narayanan D, Samuel H. Pepkowitz, James Mirocha, Tapson, Michael I. Lewis, Josephine Hwang, Sara Ghandehari, Catherine Bresee, Donald G. Stein, Ghandehari H, Yuri Matusov, Stephanie H Chang, Kaderi T, Robert I Goodman
Publikováno v:
SSRN Electronic Journal.
Background: Severity of illness and mortality from coronavirus disease 2019 (COVID-19) is consistently lower in women than in men. While this outcome difference is not well understood, focus on sex as a biologic factor may suggest potential therapeut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac62a87536b240805d3d0b49e5baaf71
https://doi.org/10.2139/ssrn.3709835
https://doi.org/10.2139/ssrn.3709835
Autor:
Anna I Scott, Qin Sun, Stephen I. Goodman, Renata C. Gallagher, Suzette Huguenin, Laura Pollard
Publikováno v:
Genetics in Medicine. 20:683-691
Organic acid analysis detects accumulation of organic acids in urine and other body fluids and is a crucial first-tier laboratory test for a broad spectrum of inborn errors of metabolism. It is also frequently ordered as follow-up for a positive newb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d24dddb8d0240d25d6ca43a4f8a284f
https://doi.org/10.1038/gim.2018.45
https://doi.org/10.1038/gim.2018.45
Autor:
Jay I. Goodman
Publikováno v:
Toxicology Research. 7:558-564
It is time to say goodbye to the standard two-year rodent bioassay. While a few, primarily genotoxic, compounds which are clearly associated with human cancer test positive in the bioassay, there is no science-based, sound foundation for presuming it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85781f90ccee0c7d234920997587a9cf
https://doi.org/10.1039/c8tx00004b
https://doi.org/10.1039/c8tx00004b
Autor:
Maria Elisa Calcagnotto, Letícia Barbieri Caus, Marcelo Ganzella, Samanta Oliveira Loureiro, Diogo O. Souza, Letícia Meier, Stephen I. Goodman, David M. Koeller, Michael Woontner, Mayara Vendramin Pasquetti, Bernardo Junges, Moacir Wajner, Alexandre Umpierrez Amaral
Publikováno v:
Epilepsia. 58:1771-1781
SummaryObjectives Glutaric acidemia type I (GA-I) is an inherited neurometabolic disorder caused by deficiency of glutaryl-CoA dehydrogenase (GCDH) and characterized by increased levels of glutaric, 3-OH-glutaric, and glutaconic acids in the brain pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78e5501bdc43c4ff0b91bb6f0d90c26a
https://doi.org/10.1111/epi.13862
https://doi.org/10.1111/epi.13862
Autor:
Jay I. Goodman
Publikováno v:
Current Opinion in Toxicology. 3:20-24
The rapidly evolving field of epigenetic regulation of gene expression is having an impact across the spectrum of biomedical research. Toxicologists have embraced this area as evidenced by their increasing focus on discerning potential epigenetic mec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4801e737f13de6873bd77effa46f814
https://doi.org/10.1016/j.cotox.2017.05.001
https://doi.org/10.1016/j.cotox.2017.05.001