Zobrazeno 1 - 8
of 8
pro vyhledávání: '"A I, Bobruskin"'
Publikováno v:
Russian Journal of Bioorganic Chemistry. 41:357-363
A new solubilization method of recombinant interferon beta-1b (IFNβ-1b) from the inclusion bodies was developed. This method allows to extract the target protein selectively in the solutions of different alcohols, such as ethanol, propanol and isopr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7b4e39790502acf637ae2840ad0a7bb
https://doi.org/10.1134/s1068162015040159
https://doi.org/10.1134/s1068162015040159
Autor:
A. M. Zhuravko, S. V. Minaev, N. V. Kononova, N. N. Pankeev, V. A. Mart’yanov, A. V. Yakovlev, A. I. Bobruskin
Publikováno v:
Russian Journal of Bioorganic Chemistry. 40:507-515
We developed a unified process platform for two recombinant human GCSF medicines--one with the non-prolonged and the other with prolonged action. This unified technology led to a simpler and cheaper production while introduction of the additional peg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ac3a0b0ef4edebdb8dbac5b5f6d0e78
https://doi.org/10.1134/s1068162014050161
https://doi.org/10.1134/s1068162014050161
Autor:
A. M. Shuster, I. A. Puchkov, A. I. Bobruskin, N. V. Kononova, D. I. Bairamashvili, V. A. Mart’yanov
Publikováno v:
Russian Journal of Bioorganic Chemistry. 38:479-487
In order to create an active pharmaceutical substance of the drug with prolonged action the modification of recombinant human granulocyte colony-stimulating factor GCSF (filgrastim) with polyethylene glycol (PEG, M 21.5 kDa) was conducted. A method f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e81b977e88297c72b21db317fc2aac0
https://doi.org/10.1134/s1068162012050111
https://doi.org/10.1134/s1068162012050111
Autor:
N. V. Kononova, V. A. Mart’yanov, A. A. Zinchenko, A. A. Vainson, T. D. Melikhova, E. V. Sveshnikova, T. I. Kostromina, A. I. Bobruskin, A. V. Demin, D. I. Bairamashvili, A. M. Shuster
Publikováno v:
Applied Biochemistry and Microbiology. 46:726-732
Technology of industrial production of an active pharmaceutical substance (APS) of the recombinant human granulocyte colony-stimulating factor (rhG-CSF) involved the use of a highly productive E. coli strain capable of biosynthesis of rhG-CSF in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::463e9a9c997047ce66762b527e88494f
https://doi.org/10.1134/s0003683810070082
https://doi.org/10.1134/s0003683810070082
Publikováno v:
Bioorganicheskaia khimiia. 41(4)
A new solubilization method of recombinant interferon beta-1b (IFNβ-1b) from the inclusion bodies was developed. This method allows to extract the target protein selectively in the solutions of different alcohols, such as ethanol, propanol and isopr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dc904b183a05b08264a98a05aa931482
https://pubmed.ncbi.nlm.nih.gov/26615635
https://pubmed.ncbi.nlm.nih.gov/26615635
Autor:
N V, Kononova, A V, Iakovlev, A M, Zhuravko, N N, Pankeev, S V, Minaev, A I, Bobruskin, V A, Mart'ianov
Publikováno v:
Bioorganicheskaia khimiia. 40(5)
We developed a unified process platform for two recombinant human GCSF medicines--one with the non-prolonged and the other with prolonged action. This unified technology led to a simpler and cheaper production while introduction of the additional peg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::39957b3ac4b3d66971281c70b1427e4f
https://pubmed.ncbi.nlm.nih.gov/25895350
https://pubmed.ncbi.nlm.nih.gov/25895350
Autor:
Jörg Kreuter, Sebastian C.J. Steiniger, Alexander S. Khalansky, Reiner Uhl, Zoya S Smirnova, I. N. Skidan, Svetlana Gelperina, Alexey I Bobruskin, Martin Kock, Sergey E Severin, Kathrin D. Geiger
Publikováno v:
International Journal of Cancer. 109:759-767
Glioblastomas belong to the most aggressive human cancers with short survival times. Due to the blood-brain barrier, they are mostly inaccessible to traditional chemotherapy. We have recently shown that doxorubicin bound to polysorbate-coated nanopar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57d704f9a396af9c16c6859601bbdbd7
https://doi.org/10.1002/ijc.20048
https://doi.org/10.1002/ijc.20048
Autor:
I N, Skidan, A I, Bobruskin, A E, Guliaev, S D, Shalkharbaeva, S E, Severin, S, Steinniger, J, Kreuter, S E, Gel'perina
Publikováno v:
Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic]. 46(4)
The present study is dedicated to investigation of pharmacokinetics of the colloidal delivery system based on polybutylcyanoacrylate nanoparticles for the II generation photosensitizer Photosense. Free or nanoparticle-bound Photosense was injected in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8eaa5a38d52e6df3ddfe1d6bee18e408
https://pubmed.ncbi.nlm.nih.gov/11550508
https://pubmed.ncbi.nlm.nih.gov/11550508