A serologically assessed neo-epitope biomarker of cellular fibronectin degradation is related to pulmonary fibrosis

Autor: Hummersgaard Hansen, Annika, Wallem Breisnes, Helene, Skovhus Prior, Thomas, Hilberg, Ole, Guldager Kring Rasmussen, Daniel, Genovese, Federica, Vestergaard Lukassen, Marie, Svensson, Birte, Løcke Langholm, Lasse, Manon-Jensen, Tina, Asser Karsdal, Morten, Julie Leeming, Diana, Bendstrup, Elisabeth, Marie Bülow Sand, Jannie

Publikováno v: Hummersgaard Hansen, A, Wallem Breisnes, H, Skovhus Prior, T, Hilberg, O, Guldager Kring Rasmussen, D, Genovese, F, Vestergaard Lukassen, M, Svensson, B, Løcke Langholm, L, Manon-Jensen, T, Asser Karsdal, M, Julie Leeming, D, Bendstrup, E & Marie Bülow Sand, J 2023, ' A serologically assessed neo-epitope biomarker of cellular fibronectin degradation is related to pulmonary fibrosis ', Clinical Biochemistry, vol. 118, 110599 . https://doi.org/10.1016/j.clinbiochem.2023.110599

Background: Idiopathic pulmonary fibrosis (IPF) is characterized by excessive extracellular matrix (ECM) remodeling, herein ECM degradation. Fibronectin (FN) is an important component of the ECM that is produced by multiple cell types, including fibr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1202::0f2de2d25cf7f2565569527690e23519
https://orbit.dtu.dk/en/publications/ccab9e12-d6bf-4647-ba46-9083a270dc36

A lung and kidney specific fragment of type IV collagen is associated with increased mortality in idiopathic pulmonary fibrosis

Autor: A Hummersgaard Hansen, T S Prior, D J Leeming, M A Karsdal, J M B Sand, E Bendstrup

Publikováno v: 03.03 - Mechanisms of lung injury and repair.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d7f78f646fe17fab745da75a4f61faa1
https://doi.org/10.1183/13993003.congress-2022.1703

A serum biomarker reflecting human neutrophil elastase degraded calprotectin is elevated in COPD and IPF

Autor: Jannie M.B. Sand, Joachim Høg Mortensen, Anne-Christine Bay-Jensen, Morten A. Karsdal, A Hummersgaard Hansen, D.J. Leeming, Sarah Rønnow

Publikováno v: 03.01 - Molecular pathology and funct. genomics.

Background: Neutrophils play a crucial role in pathogenesis of chronic obstructive pulmonary disease (COPD) and idiopathic pulmonary fibrosis (IPF). Upon activation, neutrophils can degranulate multiple protein species in an immune response, herein c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5ae6a4880221478a4749f6685b8d81ba
https://doi.org/10.1183/23120541.lsc-2021.86