In vitro neutrophil migration is associated with inhaled corticosteroid treatment and serum cytokines in pediatric asthma

Autor: Solveig Lemmel, Markus Weckmann, Anna Wohlers, Adan Chari Jirmo, Ruth Grychtol, Isabell Ricklefs, Gyde Nissen, Anna Bachmann, Shantanu Singh, Juan Caicedo, Thomas Bahmer, Gesine Hansen, Erika Von Mutius, Klaus F. Rabe, Oliver Fuchs, Anna-Maria Dittrich, Bianca Schaub, Christine Happle, Anne E. Carpenter, Matthias Volkmar Kopp, Tim Becker, the ALLIANCE Study Group as part of the German Centre for Lung Research (DZL), Mustafa Abdo, Miguel Alcazar, Mira Berbig, Heike Biller, Xenia Bovermann, Folke Brinkmann, Mifflin-Rae Calveron, David S. DeLuca, Gesa Diekmann, Christian Dopfer, Markus Ege, Svenja Foth, Svenja Gaedcke, Karoline I. Gaede, Anika Habener, Christian Herzmann, Alexander Hose, Sabina Illi, Anne-Marie Kirsten, Naschla Kohistani-Greif, Inke R. König, Silke Van Koningsbruggen-Rietschel, Matthias V. Kopp, Johanna Kurz, Katja Landgraf-Rauf, Kristina Laubhahn, Lena Liboschik, Claudia Liebl, Berrit Liselotte Husstedt, Bin Liu, Nicole Maison, Aydin Malik, Carola Marzi, Meike Meyer, Catharina Nitsche, Frauke Pedersen, Mareike Price, Harald Renz, Ernst Rietschel, Barbara Roesler, Christina Schauberger, Tom Schildberg, Carsten Schmidt-Weber, Nicolaus Schwerk, Chrysanthi Skevaki, Alena Steinmetz, Laila Sultansei, Marlen Szewczyk, Dominik Thiele, Vera Veith, Gesche Voigt, Benjamin Waschki, Henrik Watz, Stefanie Weber, Nils Welchering, Esther Zeitlmann, Ulrich Zissler

Publikováno v: Frontiers in Pharmacology, Vol 13 (2022)

Background: Different asthma phenotypes are driven by molecular endotypes. A Th1-high phenotype is linked to severe, therapy-refractory asthma, subclinical infections and neutrophil inflammation. Previously, we found neutrophil granulocytes (NGs) fro

Externí odkaz: https://doaj.org/article/fc7e3e168608484cb6c82625730f72c5

Glucagon-like peptide 1 (GLP-1)

Autor: Müller, T.D., Finan, B., Bloom, S.R., D'Alessio, D., Drucker, D.J., Flatt, P.R., Fritsche, A., Gribble, F., Grill, H.J., Habener, J.F., Holst, J.J., Langhans, W., Meier, J.J., Nauck, M.A., Perez-Tilve, D., Pocai, A., Reimann, F., Sandoval, D.A., Schwartz, T.W., Seeley, R.J., Stemmer, K., Tang-Christensen, M., Woods, S.C., DiMarchi, R.D., Tschöp, M.H.

Publikováno v: In Molecular Metabolism December 2019 30:72-130

Leptin Inhibits Insulin Gene Transcription and Reverses Hyperinsulinemia in Leptin-Deficient ob/ob Mice

Autor: Seufert, Jochen, Kieffer, Timothy J., Habener, Joel F.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America, 1999 Jan . 96(2), 674-679.

Externí odkaz: https://www.jstor.org/stable/46870

cAMP Inducibility of Transcriptional Repressor ICER in Developing and Mature Human T Lymphocytes

Autor: Bodor, Josef, Spetz, Anna-Lena, Strominger, Jack L., Habener, Joel F.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America, 1996 Apr . 93(8), 3536-3541.

Externí odkaz: https://www.jstor.org/stable/38997

Absence of Regulatory T Cells Causes Phenotypic and Functional Switch in Murine Peritoneal Macrophages

Autor: Jelena Skuljec, Adan Chari Jirmo, Anika Habener, Steven R. Talbot, Refik Pul, Ruth Grychtol, Malik Aydin, Christoph Kleinschnitz, Christine Happle, Gesine Hansen

Publikováno v: Frontiers in Immunology, Vol 9 (2018)

Tissue macrophages are important components of tissue homeostasis and inflammatory pathologies. In the peritoneal cavity, resident macrophages interact with a variety of immune cells and can exhibit broad range of phenotypes and functions. Forkhead-b

Externí odkaz: https://doaj.org/article/22fca28064b6464480e6aa578f9d9c1d