Zobrazeno 1 - 10
of 842
pro vyhledávání: '"A H, Meijer"'
Autor:
Ruben C. Boot, Anouk van der Net, Christos Gogou, Pranav Mehta, Dimphna H. Meijer, Gijsje H. Koenderink, Pouyan E. Boukany
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Tissue surface tension influences cell sorting and tissue fusion. Earlier mechanical studies suggest that multicellular spheroids actively reinforce their surface tension with applied force. Here we study this open question through high-thro
Externí odkaz:
https://doaj.org/article/ad26692b98b44a10bab8265e916896a9
Autor:
Robin H. G. A. van den Biggelaar, Kimberley V. Walburg, Susan J. F. van den Eeden, Cassandra L. R. van Doorn, Eugenia Meiler, Alex S. de Ries, M. Chiara Fusco, Annemarie H. Meijer, Tom H. M. Ottenhoff, Anno Saris
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract The emergence of antimicrobial resistance has created an urgent need for alternative treatments against bacterial pathogens. Here, we investigated kinase inhibitors as potential host-directed therapies (HDTs) against intracellular bacteria,
Externí odkaz:
https://doaj.org/article/6fef437e9d004484ab19c1ec22e82119
Autor:
Christos Gogou, J. Wouter Beugelink, Cátia P. Frias, Leanid Kresik, Natalia Jaroszynska, Uwe Drescher, Bert J. C. Janssen, Robert Hindges, Dimphna H. Meijer
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Neuronal network formation is facilitated by recognition between synaptic cell adhesion molecules at the cell surface. Alternative splicing of cell adhesion molecules provides additional specificity in forming neuronal connections. For the t
Externí odkaz:
https://doaj.org/article/7755a7b835704dd8869e2fbd3bcc9be6
Autor:
Gül Kilinç, Ralf Boland, Matthias T. Heemskerk, Herman P. Spaink, Mariëlle C. Haks, Michiel van der Vaart, Tom H. M. Ottenhoff, Annemarie H. Meijer, Anno Saris
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 8 (2024)
ABSTRACT Mycobacterium tuberculosis (Mtb) as well as nontuberculous mycobacteria are intracellular pathogens whose treatment is extensive and increasingly impaired due to the rise of mycobacterial drug resistance. The loss of antibiotic efficacy has
Externí odkaz:
https://doaj.org/article/2939a79ee24140a7a75c5c4c4f1addde
Autor:
Ron P. Dirks, Anita Ordas, Susanne Jong-Raadsen, Sebastiaan A. Brittijn, Mariëlle C. Haks, Christiaan V. Henkel, Katarina Oravcova, Peter I. Racz, Nynke Tuinhof-Koelma, Malgorzata I. Korzeniowska nee Wiweger, Stephen H. Gillespie, Annemarie H. Meijer, Tom H. M. Ottenhoff, Hans J. Jansen, Herman P. Spaink
Publikováno v:
Biology, Vol 13, Iss 9, p 688 (2024)
Zebrafish is a natural host of various Mycobacterium species and a surrogate model organism for tuberculosis research. Mycobacterium marinum is evolutionarily one of the closest non-tuberculous species related to M. tuberculosis and shares the majori
Externí odkaz:
https://doaj.org/article/012fc30884164128a2ce1e147383f949
Autor:
Robin H. G. A. van den Biggelaar, Kimberley V. Walburg, Susan J. F. van den Eeden, Cassandra L. R. van Doorn, Eugenia Meiler, Alex S. de Ries, Annemarie H. Meijer, Tom H. M. Ottenhoff, Anno Saris
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
The increasing prevalence of antimicrobial-resistant Staphylococcus aureus strains, especially methicillin-resistant S. aureus (MRSA), poses a threat to successful antibiotic treatment. Unsuccessful attempts to develop a vaccine and rising resistance
Externí odkaz:
https://doaj.org/article/d4a0576083104c598b9a431663c54c44
Autor:
Ilona van Alen, Mayra A. Aguirre García, Janneke J. Maaskant, Coenraad P. Kuijl, Wilbert Bitter, Annemarie H. Meijer, Marcellus Ubbink
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract The β-lactamase of Mycobacterium tuberculosis, BlaC, hydrolyzes β-lactam antibiotics, hindering the use of these antibiotics for the treatment of tuberculosis. Inhibitors, such as avibactam, can reversibly inhibit the enzyme, allowing for
Externí odkaz:
https://doaj.org/article/a12ee8f2c8fe4e89934290ceb65b2da1
Autor:
Jiajun Xie, Annemarie H. Meijer
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2024)
Anti-bacterial autophagy, also known as xenophagy, is a crucial innate immune process that helps maintain cellular homeostasis by targeting invading microbes. This defense pathway is widely studied in the context of infections with mycobacteria, the
Externí odkaz:
https://doaj.org/article/91e019a4e76e46c2994b5be1c4651793
Autor:
Samrah Masud, Jiajun Xie, Bart J.M. Grijmans, Sander van der Kooij, Rui Zhang, Tomasz K. Prajsnar, Annemarie H. Meijer
Publikováno v:
Autophagy Reports, Vol 2, Iss 1 (2023)
DRAM1 is an infection inducible autophagy modulator, previously shown to promote autophagic and lysosomal defense responses against the intracellular pathogen Mycobacterium marinum. However, its possible role in other anti-bacterial autophagic mechan
Externí odkaz:
https://doaj.org/article/b5e9550099de47c6a55374bec8032b0b
Autor:
Lucas M. P. Chataigner, Christos Gogou, Maurits A. den Boer, Cátia P. Frias, Dominique M. E. Thies-Weesie, Joke C. M. Granneman, Albert J. R. Heck, Dimphna H. Meijer, Bert J. C. Janssen
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
In this work the authors show how a combination of glycosylations, rigid and flexible parts within neurofascin 155 and contactin 1 define a 7.4 nm distance at the myelin-axon interface and allow bridging of three-fold larger distances in the synapse.
Externí odkaz:
https://doaj.org/article/513723d5ffb7423c95683e8e1a05d211