Zobrazeno 1 - 10
of 1 907
pro vyhledávání: '"A H, Meier"'
A structural rationale for reversible vs irreversible amyloid fibril formation from a single protein
Autor:
Lukas Frey, Jiangtao Zhou, Gea Cereghetti, Marco E. Weber, David Rhyner, Aditya Pokharna, Luca Wenchel, Harindranath Kadavath, Yiping Cao, Beat H. Meier, Matthias Peter, Jason Greenwald, Roland Riek, Raffaele Mezzenga
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract Reversible and irreversible amyloids are two diverging cases of protein (mis)folding associated with the cross-β motif in the protein folding and aggregation energy landscape. Yet, the molecular origins responsible for the formation of reve
Externí odkaz:
https://doaj.org/article/8b5b5edb4fa34aebba0ca7e2954be041
The assembly platform FimD is required to obtain the most stable quaternary structure of type 1 pili
Autor:
Dawid S. Zyla, Thomas Wiegand, Paul Bachmann, Rafal Zdanowicz, Christoph Giese, Beat H. Meier, Gabriel Waksman, Manuela K. Hospenthal, Rudi Glockshuber
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Type 1 pili are important virulence factors of uropathogenic Escherichia coli that mediate bacterial attachment to epithelial cells in the urinary tract. The pilus rod is comprised of thousands of copies of the main structural subunit FimA a
Externí odkaz:
https://doaj.org/article/884d08eb71b24e7aa30ce532b269e3b7
Autor:
Johannes J. Fürst, David Farías-Barahona, Norbert Blindow, Gino Casassa, Guisella Gacitúa, Michèle Koppes, Emanuele Lodolo, Romain Millan, Masahiro Minowa, Jérémie Mouginot, Michał Pȩtlicki, Eric Rignot, Andres Rivera, Pedro Skvarca, Martin Stuefer, Shin Sugiyama, José Uribe, Rodrigo Zamora, Matthias H. Braun, Fabien Gillet-Chaulet, Philipp Malz, Wolfgang J.-H. Meier, Marius Schaefer
Publikováno v:
Communications Earth & Environment, Vol 5, Iss 1, Pp 1-10 (2024)
Abstract The two vast Patagonian icefields are a global hotspot for ice-loss. However, not much is known about the total ice volume they store - let alone its spatial distribution. One reason is that the abundant record of direct thickness measuremen
Externí odkaz:
https://doaj.org/article/10075dff181143f386644deb8a277538
Autor:
Sara Pfister, Julius Rabl, Thomas Wiegand, Simone Mattei, Alexander A. Malär, Lauriane Lecoq, Stefan Seitz, Ralf Bartenschlager, Anja Böckmann, Michael Nassal, Daniel Boehringer, Beat H. Meier
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Nackednaviruses and hepatitis B virus (HBV) have a common non-enveloped viral ancestor. While HBV acquired an envelope during evolution, nackednaviruses remained non-enveloped. Here, Pfister et al. apply CryoEM and NMR to characterize the capsid stru
Externí odkaz:
https://doaj.org/article/8c260d6601c645e1a548bd8179f2151e
Autor:
Lauriane Lecoq, Louis Brigandat, Rebecca Huber, Marie-Laure Fogeron, Shishan Wang, Marie Dujardin, Mathilde Briday, Thomas Wiegand, Morgane Callon, Alexander Malär, David Durantel, Dara Burdette, Jan Martin Berke, Beat H. Meier, Michael Nassal, Anja Böckmann
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Hepatitis B virus (HBV) capsid assembly modulators (CAM) represent a recent class of anti-HBV antivirals. Structural approaches provide limited conformational information on the CAM-induced off-path assemblies. Here, authors use solid-state NMR to es
Externí odkaz:
https://doaj.org/article/f91900044dae4b51a0f7e494c6893cce
Autor:
Raphael P. H. Meier, Miguel Nunez, Shareef M. Syed, Sandy Feng, Mehdi Tavakol, Chris E. Freise, John P. Roberts, Nancy L. Ascher, Ryutaro Hirose, Garrett R. Roll
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionDonation after circulatory death (DCD) liver transplantation (LT) makes up well less than 1% of all LTs with a Model for End-Stage Liver Disease (MELD)≥35 in the United States. We hypothesized DCD-LT yields acceptable ischemia-reperfusi
Externí odkaz:
https://doaj.org/article/ce89c4efc4b14c439ed3265a14ec94c0
Autor:
Alexandre Balaphas, Jeremy Meyer, Raphael P. H. Meier, Emilie Liot, Nicolas C. Buchs, Bruno Roche, Christian Toso, Leo H. Bühler, Carmen Gonelle-Gispert, Frédéric Ris
Publikováno v:
Cells, Vol 12, Iss 24, p 2857 (2023)
The authors would like to add a new reference to the section “3 [...]
Externí odkaz:
https://doaj.org/article/a4ebe45f74ba4454b5d0efdc3f70b8c3
Publikováno v:
Journal of Cannabis Research, Vol 4, Iss 1, Pp 1-7 (2022)
Abstract Background Cannabis legalization has resulted in the proliferation of cannabis products. Participants’ familiarity with terms for these products may have implications for assessment, as unfamiliarity with particular terms may result in und
Externí odkaz:
https://doaj.org/article/bdfbf85b4db543e9876af3439bd92034
Autor:
V. Římal, M. Callon, A. A. Malär, R. Cadalbert, A. Torosyan, T. Wiegand, M. Ernst, A. Böckmann, B. H. Meier
Publikováno v:
Magnetic Resonance, Vol 3, Pp 15-26 (2022)
With the advent of faster magic-angle spinning (MAS) and higher magnetic fields, the resolution of biomolecular solid-state nuclear magnetic resonance (NMR) spectra has been continuously increasing. As a direct consequence, the always narrower spectr
Externí odkaz:
https://doaj.org/article/ee9d584874d04c87a18f059bbc6af018
Autor:
Cassandra Ballou, Franca Barton, Elizabeth H. Payne, Thierry Berney, Jean Villard, Raphael P. H. Meier, David Baidal, Rodolfo Alejandro, Mark Robien, Thomas L. Eggerman, Malek Kamoun, Yannick D. Muller
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionIn pancreatic islet transplantation, the exact contribution of human leukocyte antigen (HLA) matching to graft survival remains unclear. Islets may be exposed to allogenic rejection but also the recurrence of type 1 diabetes (T1D). We eva
Externí odkaz:
https://doaj.org/article/ab5fe12e7b5f403187d417443ff49ddc