Zobrazeno 1 - 10
of 124
pro vyhledávání: '"A G Scicli"'
Autor:
Branislava Janic, Austin M Guo, A S M Iskander, Nadimpalli Ravi S Varma, Alfonso G Scicli, Ali S Arbab
Publikováno v:
PLoS ONE, Vol 5, Iss 2, p e9173 (2010)
Stem cells/progenitors are central to the development of cell therapy approaches for vascular ischemic diseases. The crucial step in rescuing tissues from ischemia is improvement of vascularization that can be achieved by promoting neovascularization
Externí odkaz:
https://doaj.org/article/c070b3aaa56b4c80b2d30ddc2d08d605
Autor:
Bhagelu R. Achyut, Robert A. Knight, Ali S. Arbab, Alfonso G. Scicli, Roxan Ara, Adarsh Shankar, A. S.M. Iskander
Publikováno v:
Cancer Biology & Therapy. 17:280-290
Bone marrow derived cells (BMDCs) have been shown to contribute in the tumor development. In vivo animal models to investigate the role of BMDCs in tumor development are poorly explored. We established a novel chimeric mouse model using as low as 5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53d1aac1f3b01e005987d23dcc9994ec
https://doi.org/10.1080/15384047.2016.1139243
https://doi.org/10.1080/15384047.2016.1139243
Autor:
Bhagelu R. Achyut, Ali S. Arbab, Kartik Angara, Alfonso G. Scicli, Peng Zeng, Robert A. Knight, Roxan Ara, Adarsh Shankar, A. S.M. Iskander
Publikováno v:
Cancer Letters. 369:416-426
Glioblastoma (GBM) is a hypervascular and malignant form of brain tumors. Anti-angiogenic therapies (AAT) were used as an adjuvant against VEGF-VEGFR pathway to normalize blood vessels in clinical and preclinical studies, which resulted into marked h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::274709d9e84247bbc2c4670c3a1cec8c
https://doi.org/10.1016/j.canlet.2015.09.004
https://doi.org/10.1016/j.canlet.2015.09.004
Autor:
Austin M. Guo, John R. Falck, Ali S. Arbab, A. Guillermo Scicli, Norman L. Lehman, Ju Sheng, G Scicli, Paul A. Edwards, Richard J. Roman
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 327:10-19
Exogenous 20-hydroxyeicosatetraenoic acid (20-HETE) increases the growth of human glioma cells in vitro. However, glioma cells in culture show negligible 20-HETE synthesis. We examined whether inducing the expression of a 20-HETE synthase in a human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b9c57cbf150987eac707bde2ff9f729
https://doi.org/10.1124/jpet.108.140889
https://doi.org/10.1124/jpet.108.140889
Autor:
Meng Guo, G Scicli, Ping Chen, Paul A. Edwards, A. Guillermo Scicli, Joseph D. Fenstermacher, David Dahl
Publikováno v:
Experimental Eye Research. 83:1041-1051
To study if the endogenous renin-angiotensin system affects diabetic retinal leukostasis, rats with streptozotocin-induced diabetes were treated with an ACE inhibitor (ramipril), an angiotensin II AT(1) receptor antagonist (losartan) and the Ca chann
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdfc0ea9cc6f0c3a24d4eb7b804759a9
https://doi.org/10.1016/j.exer.2006.05.009
https://doi.org/10.1016/j.exer.2006.05.009
Publikováno v:
Microvascular Research. 63:304-315
The angiogenic vascular endothelial growth factor (VEGF) is believed to play a critical role in endothelial cell proliferation, differentiation, and sprouting. Small molecules that selectively inhibit the VEGF receptor-associated tyrosine kinase acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84643f84b96a66596ceafd25b9ed5e27
https://doi.org/10.1006/mvre.2001.2383
https://doi.org/10.1006/mvre.2001.2383
Autor:
Li Chen, Fank F Zhang, Katherine H Gotlinger, John C Falck, Alfonso G Scicli, Michal L Schwartzman, Austin M Guo
Publikováno v:
Hypertension. 64
Objective: Compensatory neovascularizaiton is an important adaptation for recovery from critical ischemia. Recent studies identified the CYP4A-20-HETE system as a novel regulator of angiogenic processes. Here, we assessed the contribution of the 20-H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2382752b60b2febb0139fb69a6bf986
https://doi.org/10.1161/hyp.64.suppl_1.338
https://doi.org/10.1161/hyp.64.suppl_1.338
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 279:H116-H121
Ischemic preconditioning is known to protect the myocardium from ischemia-reperfusion injury. We examined the transmural release of bradykinin during myocardial ischemia and the influence of ischemic preconditioning on bradykinin release during subse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::967fc673e72ed9cd02c52571f43ff48d
https://doi.org/10.1152/ajpheart.2000.279.1.h116
https://doi.org/10.1152/ajpheart.2000.279.1.h116
Publikováno v:
Hypertension. 30:217-221
Abstract Angiotensin-(1-7) [Ang-(1-7)] reportedly potentiates hypotensive responses to bradykinin. We studied whether increases in circulating bradykinin would alter responses to Ang-(1-7). In rats anesthetized with thiobutabarbital, bradykinin infus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7edb70382eb8e6473d84d221d0384e6
https://doi.org/10.1161/01.hyp.30.2.217
https://doi.org/10.1161/01.hyp.30.2.217
Autor:
A. G. Scicli, L. A. Carbini
Publikováno v:
American Journal of Physiology-Cell Physiology. 272:C1578-C1585
Submandibular enzymatic vasoconstrictor (SEV, rK9) induces vascular contraction and platelet aggregation by a mechanism requiring intact enzymatic activity. On the basis of a published report demonstrating growth-promoting enzymatic activity in an ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::517ab1b22952e370a4c991f9c57a083e
https://doi.org/10.1152/ajpcell.1997.272.5.c1578
https://doi.org/10.1152/ajpcell.1997.272.5.c1578