Optimised treatment of patients with enlarged lateral lymph nodes in rectal cancer: protocol of an international, multicentre, prospective registration study after extensive multidisciplinary training (LaNoReC)

Autor: Susan Van Dieren, Joost Nederend, Pieter J Tanis, Roel Hompes, Klaas Havenga, Melissa W Taggart, Robert Riedl, Michail Doukas, Evert-Jan G. Boerma, Marinke Westerterp, Corrie A M Marijnen, Jaap Stoker, Andrew Ruszkiewicz, Tsuyoshi Konishi, Jarno Melenhorst, Karin Muller, Krista Gerbrands, Michael Croft, Michael Wilks, Johanne G. Bloemen, Peter A. Neijenhuis, Koen C.M.J. Peeters, Miranda Kusters, Martijn Intven, Jan Peringa, Maria Verseveld, Eline G M van Geffen, Tania C Sluckin, Sanne-Marije J A Hazen, Karin Horsthuis, Geerard Beets, Marilyne M Lange, Regina G H Beets-Tan, Marc R. W. Engelbrecht, Elisabeth D. Geijsen, Philip Meijnen, Jurriaan B. Tuynman, Ingrid M. Bruijnzeel, Bas Lamme, Femke M. Alberts, Rogier M. P. H. Crolla, Joanne Verdult, Johan H. Wijsman, Charlotte S. van Kessel, Erik Jan Mulder, Jan Binne Hulshoff, Ivan M. Cherepanin, Hans F. J. Fabry, G. Y. Mireille, Frank J. M. Kemper, Fatih Polat, Jacobus W. A. Burger, Jeltsje S. Cnossen, Shira H. de Bie, Robbert J. I. Bosker, Aaldert K. Talsma, Leonora S. F. Boogerd, Marc J. P. M. Govaert, Merel M. Scheurkogel, Imogeen E. Antonisse, Joost Rothbarth, Marianne de Vries, Marcel A. H. Ribbert, Anthony W. H. van de Ven, Susan ter Borg, Jennifer W. Bradshaw, Heleen M. Ceha, Fleur I. de Korte, Andreas W. K. S. Marinelli, Tjeerd S. Aukema, Liselotte W. van Bockel, Aukje A. J. M. van Tilborg, Tom Rozema, Amarins Brandsma, Stefan Hoogendoorn, Saskia R. Offerman, Hanneke Vos, Henderik L. van Westreenen, Jeroen W. A. Leijtens, Fabian A. Holman, Laura A. Velema, L Els, van Persijn van Meerten, Frans C. H. Bakers, Iryna Samarska, Nina Šefčovičová, Maaike Berbée, Bastiaan B. Pultrum, Dennis B. Rouw, Matthew Albert, L. René Arensman, Hanneke Basart, Esther C. J. Consten, Bart C.T. van de Laar, Inne Somers, Paul M. Verheijen, Thomas A. Fassaert, Christiaan Hoff, Eino B. van Duyn, Ellen M. Hendriksen, Hugo A.J. Gielkens, Arend G. J. Aalbers, Brechtje A. Grotenhuis, Michalda S. Dunker, Anne M. van Geel, Christof Meischl, W. Hermien Schreurs, Patty H. Spruit, Michael F. Gerhards, Thomas M. Karsten, Eveline J.T. Krul, Sebastiaan van Koeverden, Andre J. A. Bremers, Heidi Rütten, Johannes H. W. de Wilt, Mariska den Hartogh, Vera Oppedijk, Jan Willem T. Dekker, Debora Eschbach-Zandbergen, Daphne Roos, Arjan van Tilburg, Ernst Jan, Spillenaar Bilgen, Nikki Knijn, Marnix A. J. de Roos, Ilse van Dop, Tracy Fitzsimmons, Hidde M. Kroon, Michael Penniment, Mitchell Raeside, Tarik Sammour, Steven J. Oosterling, Jeroen A. W. Tielbeek, Ronald J. C. L. M. Vuylsteke, Erik J. R. J. van der Hoeven, Anke B. Smits, Anniek H. Boer, Edgar J. B. Furnée, Robbert J. de Haas, Manon N. G. J. A. Braat, Wilhelmina M. U. van Grevenstein, Milan C. Richir, Patricia J. A. M. Brouwers, Tilly Leseman, Eric H. J. Belgers, Jasenko Krdzalic, Roy F. A. Vliegen

Publikováno v: BMJ Open, Vol 14, Iss 10 (2024)

Introduction Inadequate treatment of enlarged lateral lymph nodes (LLNs) in rectal cancer patients is associated with an increased lateral local recurrence (LLR) risk, despite neoadjuvant treatment and total mesorectal excision (TME) surgery. There i

Externí odkaz: https://doaj.org/article/340de40a283a4148be1229eb0c6c7cba

Dedicated MRI staging versus surgical staging of peritoneal metastases in colorectal cancer patients considered for CRS-HIPEC; the DISCO randomized multicenter trial

Autor: M. P. Engbersen, C. J. V. Rijsemus, J. Nederend, A. G. J. Aalbers, I. H. J. T. de Hingh, V. Retel, D. M. J. Lambregts, E. J. R. J. Van der Hoeven, D. Boerma, M. J. Wiezer, M. De Vries, E. V. E. Madsen, A. R. M. Brandt-Kerkhof, S. Van Koeverden, P. R. De Reuver, R. G. H. Beets-Tan, N. F. M. Kok, M. J. Lahaye

Publikováno v: BMC Cancer, Vol 21, Iss 1, Pp 1-8 (2021)

Abstract Background Selecting patients with peritoneal metastases from colorectal cancer (CRCPM) who might benefit from cytoreductive surgery followed by hyperthermic intraperitoneal chemotherapy (CRS-HIPEC) is challenging. Computed tomography genera

Externí odkaz: https://doaj.org/article/6e1e96aa348a4d36926080366498329d

Perineal wound closure using gluteal turnover flap or primary closure after abdominoperineal resection for rectal cancer: study protocol of a randomised controlled multicentre trial (BIOPEX-2 study)

Autor: Sarah Sharabiany, Robin D. Blok, Oren Lapid, Roel Hompes, Wilhelmus A. Bemelman, Victor P. Alberts, Bas Lamme, Jan H. Wijsman, Jurriaan B. Tuynman, Arend G. J. Aalbers, Geerard L. Beets, Hans F. J. Fabry, Ivan M. Cherepanin, Fatih Polat, Jacobus W. A. Burger, Harm J. T. Rutten, Robert J. I. Bosker, Koen Talsma, Joost Rothbarth, Cees Verhoef, Anthony W. H. van de Ven, Jarmila D. W. van der Bilt, Eelco J. R. de Graaf, Pascal G. Doornebosch, Jeroen W. A. Leijtens, Jeroen Heemskerk, Baljit Singh, Sanjay Chaudhri, Michael F. Gerhards, Tom M. Karsten, Johannes H. W. de Wilt, Andre J. A. Bremers, Ronald J. C. L. M. Vuylsteke, Gijsbert Heuff, Anna A. W. van Geloven, Pieter J. Tanis, Gijsbert D. Musters

Publikováno v: BMC Surgery, Vol 20, Iss 1, Pp 1-8 (2020)

Abstract Background Abdominoperineal resection (APR) for rectal cancer is associated with high morbidity of the perineal wound, and controversy exists about the optimal closure technique. Primary perineal wound closure is still the standard of care i

Externí odkaz: https://doaj.org/article/7a81c2987bdc4d19a4ac5c5fbad22529

Tissue diagnosis during colorectal cancer surgery using optical sensing: an in vivo study

Autor: E. J. M. Baltussen, S. G. Brouwer de Koning, J. Sanders, A. G. J. Aalbers, N. F. M. Kok, G. L. Beets, B. H. W. Hendriks, H. J. C. M. Sterenborg, K. F. D. Kuhlmann, T. J. M. Ruers

Publikováno v: Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-10 (2019)

Abstract Background In colorectal cancer surgery there is a delicate balance between complete removal of the tumor and sparing as much healthy tissue as possible. Especially in rectal cancer, intraoperative tissue recognition could be of great benefi

Externí odkaz: https://doaj.org/article/680e800770274379aeebdd4a5f3eff76

Perioperative systemic therapy and cytoreductive surgery with HIPEC versus upfront cytoreductive surgery with HIPEC alone for isolated resectable colorectal peritoneal metastases: protocol of a multicentre, open-label, parallel-group, phase II-III, randomised, superiority study (CAIRO6)

Autor: Koen P. Rovers, Checca Bakkers, Geert A. A. M. Simkens, Jacobus W. A. Burger, Simon W. Nienhuijs, Geert-Jan M. Creemers, Anna M. J. Thijs, Alexandra R. M. Brandt-Kerkhof, Eva V. E. Madsen, Ninos Ayez, Nadine L. de Boer, Esther van Meerten, Jurriaan B. Tuynman, Miranda Kusters, Nina R. Sluiter, Henk M. W. Verheul, Hans J. van der Vliet, Marinus J. Wiezer, Djamila Boerma, Emma C. E. Wassenaar, Maartje Los, Cornelis B. Hunting, Arend G. J. Aalbers, Niels F. M. Kok, Koert F. D. Kuhlmann, Henk Boot, Myriam Chalabi, Schelto Kruijff, Lukas B. Been, Robert J. van Ginkel, Derk Jan A. de Groot, Rudolf S. N. Fehrmann, Johannes H. W. de Wilt, Andreas J. A. Bremers, Philip R. de Reuver, Sandra A. Radema, Karin H. Herbschleb, Wilhelmina M. U. van Grevenstein, Arjen J. Witkamp, Miriam Koopman, Nadia Haj Mohammad, Eino B. van Duyn, Walter J. B. Mastboom, Leonie J. M. Mekenkamp, Joost Nederend, Max J. Lahaye, Petur Snaebjornsson, Cornelis Verhoef, Hanneke W. M. van Laarhoven, Aeilko H. Zwinderman, Jeanette M. Bouma, Onno Kranenburg, Iris van ‘t Erve, Remond J. A. Fijneman, Marcel G. W. Dijkgraaf, Patrick H. J. Hemmer, Cornelis J. A. Punt, Pieter J. Tanis, Ignace H. J. T. de Hingh, Dutch Peritoneal Oncology Group (DPOG), Dutch Colorectal Cancer Group (DCCG)

Publikováno v: BMC Cancer, Vol 19, Iss 1, Pp 1-15 (2019)

Abstract Background Upfront cytoreductive surgery with HIPEC (CRS-HIPEC) is the standard treatment for isolated resectable colorectal peritoneal metastases (PM) in the Netherlands. This study investigates whether addition of perioperative systemic th

Externí odkaz: https://doaj.org/article/0eae7e00e09f44039f07a47639a0e680