Výsledky vyhledávání

Akademický článek

Intratumor morphologic and molecular genetic heterogeneity in astrocytomas of different grade of malignancy in the material from the first operation

Autor: D. E. Matsko, M. V. Matsko, A. O. Baksheeva, E. N. Imyanitov, A. Yu. Ulitin, V. M. Moiseenko, K. V. Shelekhova, N. M. Volkov, A. G. Ievleva, V. I. Tiurin, S. S. Sklyar, A. A. Zrelov, A. S. Morozova

Publikováno v: Сибирский онкологический журнал, Vol 20, Iss 6, Pp 55-68 (2022)

Introduction. Intratumor heterogeneity is one of the key reasons for unfavourable prognosis in malignant tumors. Astrocytic tumors are known to develop therapy resistance inevitably during the course of disease. One of possible reason is tumor hetero

Externí odkaz: https://doaj.org/article/450d04d7a67f403cadbf4240b2d8449c

Zobrazit plný text záznamu

Akademický článek

CHANGES IN THE MGMT GENE EXPRESSION IN PATIENTS WITH PRIMARY GLIOBLASTOMA AFTER RELAPSE. INFLUENCE OF CLINICAL CHARACTERISTICS AND MGMT EXPRESSION ON SURVIVAL OF PATIENTS

Autor: M. V. Matsko, S. S. Sklyar, A. Yu. Ulitin, D. E. Matsko, E. N. Imyanitov, A. G. Ievleva, V. I. Ni, N. M. Volkov, A. A. Zrelov, A. O. Baksheeva, D. V. Galkina

Publikováno v: Сибирский онкологический журнал, Vol 20, Iss 3, Pp 5-17 (2021)

Background. Over the past 10–15 years, there has been a clearer understanding of the processes occurring in cells of the primary glioblastoma. However, the change in MGMT gene expression and its role after disease relapse remain understudied. Purpo

Externí odkaz: https://doaj.org/article/2ffd88be1f934763882aaab2a04c4719

Zobrazit plný text záznamu

Akademický článek

EMBRYONAL TUMORS OF THE CENTRAL NERVOUS SYSTEM IN ADULTS: A REPORT OF THREE CASES. REVIEW OF THE LITERATURE

Autor: M. V. Matsko, D. E. Matsko, E. N. Imyanitov, S. S. Sklyar, A. Yu. Ulitin, I. V. Yakovenko, A. G. Ievleva, G. A. Ershov, A. A. Romanko, A. S. Nechaeva

Publikováno v: Сибирский онкологический журнал, Vol 20, Iss 1, Pp 105-114 (2021)

Background. Еmbryonal tumors of the central nervous system are malignant neoplasms that mainly occur in pediatric patients with a peak incidence at the age of 4 years. These tumors usually have small round blue cell histology and low differentiation

Externí odkaz: https://doaj.org/article/52d6446c8fa241eb98f87b2bf2567485

Zobrazit plný text záznamu

Akademický článek

PREDICTIVE RESPONSE MARKERS FOR IMMUNE RESPONSE BLOCKS

Autor: G. A. Janus, A. G. Ievleva, E. N. Suspitsyn, V. I. Tyurin, I. V. Bizin, O. A. Gorustovich, V. I. Ni, M. M. Kholmatov, T. A. Laidus, S. A. Chuynyshena, S. N. Aleksakhina, E. N. Imyanitov

Publikováno v: Сибирский онкологический журнал, Vol 19, Iss 4, Pp 123-131 (2020)

Despite the unprecedented success in using immune checkpoint inhibitors in the treatment of lung cancer, melanoma, hypermutable tumors of various localization, etc., a significant proportion of patients receiving these drugs do not respond to treatme

Externí odkaz: https://doaj.org/article/c3a2800fe9394defaa9436a7283d7c1b

Zobrazit plný text záznamu

Akademický článek

COST-EFFICACY ANALYSIS OF GEFITINIB EFFICACY IN PATIENTS WITH NON OPERABLE NON SMALL CELL LUNG CANCER

Autor: S. A. Protsenko, A. V. Rudakova, F. V. Moiseyenko, E. V. Levchenko, D. E. Matsko, A. О. Ivantsov, I. I. Semenov, A. G. Ievleva, N. V. Mitushkina, A. V. Togo, A. V. Novik, E. N. Imyanitov, V. M. Moiseyenko

Publikováno v: Креативная хирургия и онкология, Vol 0, Iss 2, Pp 46-52 (2017)

Drug treatment of disseminated non small cell lung cancer (NSCLC) is an actual issue today. Both clinical and economic efficacy analysis is needed for optimal therapy selection. We performed economic efficacy assessment of gefitinib (G.) therapy in p

Externí odkaz: https://doaj.org/article/e5b353add05b45ec86743eaa42e6c519

Zobrazit plný text záznamu

Clinical and morphological features of breast tumors with PIK3CA mutations in Russian patients: Observational study

Autor: Tatyana N. Sokolova, Tatyana I. Solov'eva, Svetlana N. Aleksakhina, Marina B. Bolieva, Viktor E. Goldberg, Marianna V. Kibisheva, Konstantin V. Menshikov, Dmitrii V. Ryazanov, Aleksandr V. Shkradyuk, Yana S. Chapko, Anna A. Shchukina, Idris M. Khabriev, Dmitrii V. Kirtbaya, Alexey M. Degtyarev, Aleksandr A. Epkhiev, Yana A. Tyugina, Aleksandr V. Togo, Mirza A. Murachuev, Aglaya G. Ievleva, Evgenii N. Imyanitov, Anna A. Grechkina, Alena S. Stel'makh, Svetlana V. Odintsova, Grigorii A. Janus, Khedi S. Musaeva, Victor L. Chang, Anastasia V. Fateeva, Ekaterina P. Startseva, Nataliya O. Popova, Yulia V. Mikheeva, Anna V. Vasilevskaya, Victoria S. Barbara, Petimat I. Khabibulaeva, Alina G. Khlobystina, Ludmila V. Bembeeva, Vladimir I. Vladimirov, Oleg L. Petrenko, Natalia G. Ruskova, Ekaterina L. Serikova, Ksenia S. Subbotina, Svetlana A. Tkachenko, Denis Y. Yukalchuk, Elena A. Basova, Mariya L. Stepanova, Sanal P. Erdniev, Alla Goryainova, Mark I. Gluzman, Rashida V. Orlova, Anastasiya I. Stukan, Ruslan A. Zukov, Alena V. Zyuzyukina, Yulia N. Murunova, Aleksandr V. Sultanbaev, Elena N. Vorobeva, Leonid M. Mikhaevich, Anna N. Lysenko, Zarema K. Khachmamuk, Andrey E. Kozlov, Sergey Y. Bakharev, Victoria N. Pyliv, Irina K. Amirkhanova, Shahen G. Parsyan, Elena I. Rossokha, Leri D. Osidze, Irina S. Shumskaya, Anna V. Agaeva, Tatiana A. Kasmynina, Veronika V. Klimenko, Kamila T. Akhmetgareeva, Almira A. Vakhitova, Madina D. Chakhkieva, Yana A. Udalova, Vadim N. Dmitriev, Yana I. Bakshun, Alexey E. Vasilyev, Dunya D, Gasimly, Nadezhda A. Kravchenko, Dmitriy A. Maksimov, Alfia I. Nesterova, Zaur M. Khamgokov, Ineza O. Sharvashidze, Christina H. Gadzaova, Galina G. Rakhmankulova, Kseniya A. Shvaiko

Publikováno v: Journal of Modern Oncology. 24:12-23

Background. By 2020, breast cancer (BC) has become the most frequent malignancy in the world. The most common type of BC is HR+/HER2-negative cancer,2540% of which harbors PIK3CA mutations that affect the catalytic subunit of the PI3K protein. PIK3CA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8c5fe18bf5e943e1b8f0117b412ee954
https://doi.org/10.26442/8151434.2022.1.201435

Zobrazit plný text záznamu

Akademický článek

BRCA1GENE EXPRESSION IN ENDOCRINE TUMORS OF THE GASTROINTESTINAL TRACT

Autor: I. G. Gafton, Е. N. Imyanitov, V. V. Semiglasov, D. Е. Matsko, G. I. Gafton, Yu. V. Semiletova, А. G. Ievleva, А. Е. Mikhnin, V. G. Lemekhov

Publikováno v: Сибирский онкологический журнал, Vol 0, Iss 4, Pp 11-15 (2016)

Results of molecular genetic study of BRCA1gene expression in patients with endocrine tumors of the gastrointestinal tract were presented. Based on the analysis of survival rates in patients with endocrine tumors of the gastrointestinal tract, the BR

Externí odkaz: https://doaj.org/article/977422c9bd4444218ee01a9f9bb3bd50

Zobrazit plný text záznamu

Akademický článek

Occurrence of BRCA1 and BRCA2 mutation in pancreatic cancer patients

Autor: A. A. Kashintsev, G. A. Yanus, N. Yu. Kokhanenko, V. M. Moiseenko, M. D. Hanevich, L. D. Roman, A. G. Ievleva, A. P. Sokolenko, E. N. Suspitsin, A. I. Budovskiy, A. V. Togo, N. M. Volkov, R. V. Fadeev, M. S. Dinikin, A. K. Ivanova, K. G. Shostko, E. N. Imyanitov

Publikováno v: Сибирский онкологический журнал, Vol 0, Iss 5, Pp 39-44 (2016)

BRCA1 and BRCA2 may contribute in pancreatic cancer (PC) risk, however the selection criteria for BRCA1 testing are poorly defined. The analysis of Russian founder mutation BRCA1 5382insC in 150 PC patients identified 2 carriers. BRCA2 full-length se

Externí odkaz: https://doaj.org/article/a3b518da81a44326890291ca8d4694ff

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání