Zobrazeno 1 - 10
of 451
pro vyhledávání: '"A G Huvos"'
Publikováno v:
Sarcoma, Vol 1, Iss 3-4, Pp 131-134 (1997)
Purpose. In a previous series of 25 human osteosarcoma samples studied for MYC gene amplification, we found amplification in two cases (8%), including one arising in association with Paget's disease (pagetic osteosarcoma). Based on this observation,
Externí odkaz:
https://doaj.org/article/856b43dc02984e5c84e0549966b6ce41
Autor:
J G, Fortner, E J, Beattie, E W, Strong, H W, Farr, J, Smith, W G, Cahan, K, Arthur, S R, Savdie, A G, Huvos
Publikováno v:
Postgraduate medicine. 51(2)
Autor:
Saminathan S Nathan, Andrew G Huvos, Jorge E Casas-Ganem, Rui Yang, Irina Linkov, Rebecca Sowers, Gene R DiResta, Richard Gorlick, John H Healey
Publikováno v:
Annals of the Academy of Medicine, Singapore. 38:1041-1047
Purpose: We have previously shown that osteosarcomas have states of increased interstitial fluid pressure (IFP) which correlate with increased proliferation and chemosensitivity. In this study, we hypothesized that constitutively raised IFP in osteos
Autor:
John H. Healey, Han-Soo Kim, Rebecca Sowers, Wen Chen, Paul A. Meyers, Tadahiko Kubo, Sajida Piperdi, Andrew G. Huvos, Jeremy Rosenblum, Richard Gorlick, Cristina R. Antonescu
Publikováno v:
Cancer. 112:2119-2129
The purpose of this review was to determine whether imatinib mesylate (STI571, Gleevec) has a role in the treatment of osteosarcoma. The expression of platelet-derived growth factor (PDGF) receptor and its ligand was examined in a panel of surgical s
Publikováno v:
Clinical Orthopaedics & Related Research. 465:265-270
We report the case of a 41-year-old woman who presented with ipsilateral synchronous low-grade juxtacortical osteogenic sarcoma of the distal femur and low-grade intramedullary osteogenic sarcoma of the proximal tibia. The diagnosis and treatment and
Autor:
Paul A. Meyers, Alexander J. Chou, Richard Gorlick, Jing Qin, Rui Yang, John H. Healey, Rebecca Sowers, Andrew G. Huvos, Bang H. Hoang, E. Anders Kolb
Publikováno v:
Clinical Cancer Research. 13:2557-2567
Purpose: Two major systems exist for folate cell entry: the reduced folate carrier (RFC) and the folate receptor (FR). Although defective RFC-mediated transport was frequently identified as a mechanism of methotrexate (MTX) resistance in osteosarcoma
Autor:
Tadahiko Kubo, Andrew G. Huvos, Rebecca Sowers, John H. Healey, Rui Yang, Hirotaka Kawano, Paul A. Meyers, Alexander J. Chou, Bang H. Hoang, Richard Gorlick
Publikováno v:
International Journal of Cancer. 121:943-954
Osteosarcoma is the most common primary bone malignancy in children and is associated with rapid bone growth. Parathyroid hormone-related peptide (PTHrP) signaling via parathyroid hormone Type 1 receptor (PTHR1) is important for skeletal development
Autor:
Richard Gorlick, John H. Healey, Saminathan S. Nathan, Andrew G. Huvos, Alexander J. Chou, Susan V. Bukata, Patrick J. Boland, Carol D. Morris, Paul A. Meyers
Publikováno v:
Cancer. 107:1607-1616
BACKGROUND. Local recurrence in osteosarcoma is clinically distinct from metastasis, although associated with a similar reduction in survival. The prognostic factors in locally recurrent osteosarcoma were investigated and these factors were translate
Autor:
Michael P. LaQuaglia, Leonard H. Wexler, Paul A. Meyers, Mark L. Kayton, Sara J. Abramson, Jennifer Casher, Nancy Rosen, Andrew G. Huvos
Publikováno v:
Journal of Pediatric Surgery. 41:200-206
Survival in osteosarcoma correlates with complete resection of primary and metastatic disease. The feasibility of complete pulmonary metastasectomy using thoracoscopy has been raised. Because palpation is not possible, minimally invasive techniques r
Autor:
Yatin M. Vyas, Alexander J. Chou, Richard Gorlick, John H. Healey, Pamela R. Merola, Leonard H. Wexler, Paul A. Meyers, Andrew G. Huvos, Michael P. LaQuaglia
Publikováno v:
Cancer. 104:2214-2221
Overall survival after recurrence of osteosarcoma (OS) is30%. The authors reported their experience treating recurrent OS at the time of first recurrence (R1).Patients with high-grade OS who achieved complete disease remission (CR) after primary surg