Zobrazeno 1 - 10
of 23
pro vyhledávání: '"A G Droogan"'
Hypokalaemic paralysis precipitated by distal renal tubular acidosis secondary to Sjögren's syndrome
Publikováno v:
Annals of Clinical Biochemistry: International Journal of Laboratory Medicine. 45:221-225
A 43-year-old woman presented with a sudden onset of hypokalaemic paralysis requiring intubation and ventilatory support. Subsequent biochemical and clinical assessments established a diagnosis of distal renal tubular acidosis (RTA) in association wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0830bcc5d60a1ac74f28bcb524949087
https://doi.org/10.1258/acb.2007.006080
https://doi.org/10.1258/acb.2007.006080
Autor:
Michael Hutchinson, Colin A. Graham, Alastair Compston, Koen Vandenbroeck, A. G. Droogan, G V McDonnell, Stephen Sawcer, Stanley Hawkins, Shirley Heggarty, Efrosini Setakis
Publikováno v:
Journal of Neuroimmunology. 143:93-96
In order to screen the genome for linkage disequilibrium (LD) in multiple sclerosis (MS), we typed 2537 microsatellite markers in separately pooled DNA from 200 cases and 200 controls from N. Ireland. Twenty two markers showing significant evidence o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9efed28311bd2d55a3844e52efa8a119
https://doi.org/10.1016/j.jneuroim.2003.08.019
https://doi.org/10.1016/j.jneuroim.2003.08.019
Publikováno v:
Multiple Sclerosis Journal. 7:83-89
Pathological changes in the normal-appearing white matter in multiple sclerosis are well recognised, but their relationship to pathology in focal lesions is not well understood. Magnetic resonance diffusion imaging is sensitive to abnormalities in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7bb3ac9737608f186a0c429c784428b
https://doi.org/10.1177/135245850100700202
https://doi.org/10.1177/135245850100700202
Publikováno v:
Magnetic Resonance Imaging. 17:653-661
The apparent diffusion coefficient (ADC) of tissue provides an indication of the size, shape, and orientation of the water spaces in tissue. Thus, pathologic differences between lesions in multiple sclerosis (MS) patients with different clinical cour
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b529d1ebd031ea5ce5e027036fb109f
https://doi.org/10.1016/s0730-725x(99)00011-9
https://doi.org/10.1016/s0730-725x(99)00011-9
Publikováno v:
Neurology. 51:1156-1160
Objective: To ascertain the presence of the Th2 response in MS patients by evaluating the level of soluble (s) CD30 across the clinical spectrum of MS and during relapse and remission.Background: MS is considered a T-cell-mediated disorder with the i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2841be4fcb9a619028c545732ace81ee
https://doi.org/10.1212/wnl.51.4.1156
https://doi.org/10.1212/wnl.51.4.1156
Publikováno v:
Journal of Neuroimmunology. 85:186-192
Endothelial activation is considered an important step in multiple sclerosis (MS) lesion formation, elevated cerebrospinal fluid (CSF) and serum levels of certain adhesion molecules being associated with varying stages of disease activity and clinica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7a7f0b3d57f9f512c5f2ff2b2684e5d
https://doi.org/10.1016/s0165-5728(98)00009-5
https://doi.org/10.1016/s0165-5728(98)00009-5
Publikováno v:
Journal of the Neurological Sciences. 147:21-25
The TNF alpha and beta genes are located between the class I and class III HLA loci and have been implicated in the pathogenesis of multiple sclerosis. We carried out allelic association analysis using four microsatellite markers localised within a 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d21cecf98bbd1650ad31d9ea7b4fcffb
https://doi.org/10.1016/s0022-510x(96)00313-9
https://doi.org/10.1016/s0022-510x(96)00313-9
Publikováno v:
Neurology. 47:1049-1053
Genetic predisposition to multiple sclerosis (MS) is determined, in part, by certain HLA genotypes, but the contribution of T-cell receptor (TCR) germline polymorphisms to MS susceptibility is less clear. Reports of disease associations with restrict
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccec9b6cd654a68b6a13ee3894377398
https://doi.org/10.1212/wnl.47.4.1049
https://doi.org/10.1212/wnl.47.4.1049
Publikováno v:
Journal of Neuroimmunology. 70:29-35
The effect of methylprednisolone on constitutive and interferon-beta (IFN-beta) induced HLA-DR expression on monocytes from multiple sclerosis (MS) patients was investigated. Constitutive HLA-DR expression was reduced by 50% following a single dose (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3ed050d72d15d982ace0ff5b9f45b2e
https://doi.org/10.1016/s0165-5728(96)00100-2
https://doi.org/10.1016/s0165-5728(96)00100-2
Publikováno v:
Journal of Neuroimmunology. 64:185-191
Activated cerebral vascular endothelial cells express leukocyte, vascular cell, and intracellular adhesion molecules (E-selectin, VCAM-1 and ICAM-1) which facilitate leukocyte adhesion to endothelium and migration into inflammatory lesions. Paired se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9e998754fcde567af7eea44235f39e5
https://doi.org/10.1016/0165-5728(95)00174-3
https://doi.org/10.1016/0165-5728(95)00174-3