Zobrazeno 1 - 10
of 624
pro vyhledávání: '"A G, Weil"'
Autor:
Augusto Faria Andrade, Alva Annett, Elham Karimi, Danai Georgia Topouza, Morteza Rezanejad, Yitong Liu, Michael McNicholas, Eduardo G. Gonzalez Santiago, Dhana Llivichuzhca-Loja, Arne Gehlhaar, Selin Jessa, Antonella De Cola, Bhavyaa Chandarana, Caterina Russo, Damien Faury, Geoffroy Danieau, Evan Puligandla, Yuhong Wei, Michele Zeinieh, Qing Wu, Steven Hebert, Nikoleta Juretic, Emily M. Nakada, Brian Krug, Valerie Larouche, Alexander G. Weil, Roy W. R. Dudley, Jason Karamchandani, Sameer Agnihotri, Daniela F. Quail, Benjamin Ellezam, Liza Konnikova, Logan A. Walsh, Manav Pathania, Claudia L. Kleinman, Nada Jabado
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Histone H3-mutant gliomas are deadly brain tumors characterized by a dysregulated epigenome and stalled differentiation. In contrast to the extensive datasets available on tumor cells, limited information exists on their tumor microenvironme
Externí odkaz:
https://doaj.org/article/69253d46aa2e495fb76b6cda5b46af80
Autor:
Sami Obaid, Guido I. Guberman, Etienne St-Onge, Emma Campbell, Manon Edde, Layton Lamsam, Alain Bouthillier, Alexander G. Weil, Alessandro Daducci, François Rheault, Dang K. Nguyen, Maxime Descoteaux
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
IntroductionOperculo-insular epilepsy (OIE) is a rare condition amenable to surgery in well-selected cases. Despite the high rate of neurological complications associated with OIE surgery, most postoperative deficits recover fully and rapidly. We pro
Externí odkaz:
https://doaj.org/article/6d84c705977f49c6a2a5cc926c668e49
Autor:
Farbod Niazi, Aline Han, Lauren Stamm, Nathan A. Shlobin, Catherine Korman, Thien S. Hoang, Agnieszka Kielian, Genevieve Du Pont-Thibodeau, Laurence Ducharme Crevier, Philippe Major, Dang K. Nguyen, Alain Bouthillier, George M. Ibrahim, Aria Fallah, Aristides Hadjinicolaou, Alexander G. Weil
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
BackgroundRefractory (RSE) and super-refractory status epilepticus (SRSE) are serious neurological conditions requiring aggressive management. Beyond anesthetic agents, there is a lack of evidence guiding management in these patients. This systematic
Externí odkaz:
https://doaj.org/article/b248978e221c4841a5efcb0f500c31c0
Autor:
Keshav Goel, Mark Keezer, Alexander G Weil, Aria Fallah, Anne Gallagher, Farbod Niazi, Jia-Shu Chen, Aristides Hadjinicolaou
Publikováno v:
BMJ Open, Vol 14, Iss 2 (2024)
Introduction Hypothalamic hamartomas (HHs) are deep-seated congenital lesions that typically lead to pharmacoresistant epilepsy and a catastrophic encephalopathic syndrome characterised by severe neuropsychological impairment and decline in quality o
Externí odkaz:
https://doaj.org/article/8ff0a00a24f04151a6c288376e14fab9
Autor:
Karim Mithani, Oliver L. Richards, Mark Ebden, Noor Malik, Ladina Greuter, Hrishikesh Suresh, Farbod Niazi, Flavia Venetucci Gouveia, Elysa Widjaja, Shelly Weiss, Elizabeth Donner, Hiroshi Otsubo, Ayako Ochi, Puneet Jain, Ivanna Yau, Elizabeth N. Kerr, James T. Rutka, James M. Drake, Alexander G. Weil, George M Ibrahim
Publikováno v:
NeuroImage: Clinical, Vol 42, Iss , Pp 103613- (2024)
Background and objectives: Gelastic seizures due to hypothalamic hamartomas (HH) are challenging to treat, in part due to an incomplete understanding of seizure propagation pathways. Although magnetic resonance imaging-guided laser interstitial therm
Externí odkaz:
https://doaj.org/article/37bb4c2d8def47998149a8827eab2218
Publikováno v:
SSM: Qualitative Research in Health, Vol 4, Iss , Pp 100365- (2023)
A polio booster campaign targeting all children aged 1–9 was implemented across London between August–December 2022 as part of a national enhanced poliovirus incident response. Orthodox Jewish (OJ) children were particularly vulnerable to transmi
Externí odkaz:
https://doaj.org/article/64a96d8127e444eca2f39cba53004f3d
Autor:
Sami Obaid, Jia‐Shu Chen, George M. Ibrahim, Alain Bouthillier, Evan Dimentberg, Werner Surbeck, Elena Guadagno, Tristan Brunette‐Clément, Nathan A. Shlobin, Aidan Shulkin, Andrew T. Hale, Luke D. Tomycz, Marec Von Lehe, Michael Scott Perry, Francine Chassoux, Viviane Bouilleret, Delphine Taussig, Martine Fohlen, Georg Dorfmuller, Koichi Hagiwara, Jean Isnard, Chima O. Oluigbo, Naoki Ikegaya, Dang K. Nguyen, Aria Fallah, Alexander G. Weil
Publikováno v:
Epilepsia Open, Vol 8, Iss 1, Pp 12-31 (2023)
Abstract Insular epilepsy (IE) is an increasingly recognized cause of drug‐resistant epilepsy amenable to surgery. However, concerns of suboptimal seizure control and permanent neurological morbidity hamper widespread adoption of surgery for IE. We
Externí odkaz:
https://doaj.org/article/85bcda8e79194d649aed912b82a55388
Autor:
Melissa Zwaig, Audrey Baguette, Bo Hu, Michael Johnston, Hussein Lakkis, Emily M. Nakada, Damien Faury, Nikoleta Juretic, Benjamin Ellezam, Alexandre G. Weil, Jason Karamchandani, Jacek Majewski, Mathieu Blanchette, Michael D. Taylor, Marco Gallo, Claudia L. Kleinman, Nada Jabado, Jiannis Ragoussis
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-13 (2022)
Abstract Background Juvenile Pilocytic Astrocytomas (JPAs) are one of the most common pediatric brain tumors, and they are driven by aberrant activation of the mitogen-activated protein kinase (MAPK) signaling pathway. RAF-fusions are the most common
Externí odkaz:
https://doaj.org/article/4381905f37b94a1eb20515d76b4091cd
Autor:
Daniele C. Wolf, Nathalie T. Sanon, Alexandra O. S. Cunha, Jia-Shu Chen, Tarek Shaker, Abdul-Rahman Elhassan, Antônia Sâmia Fernandes do Nascimento, Graziella Di Cristo, Alexander G. Weil
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Sexual differentiation of the brain is influenced by testosterone and its metabolites during the perinatal period, when many aspects of brain development, including the maturation of GABAergic transmission, occur. Whether and how testosteron
Externí odkaz:
https://doaj.org/article/708a01107ad54f98a88d85ee5edb2f12
Autor:
Howard L Weiner, Han Yan, Melissa LoPresti, Elysa Widjaja, George M Ibrahim, Lauren Siegel, Nebras Warsi, Simeon Wong, Hrishikesh Suresh, Alexander G Weil, John Ragheb, Shelly Wang, Curtis Rozzelle, Gregory W Albert, Jeffrey Raskin, Taylor Abel, Jason Hauptman, Dewi V Schrader, Robert Bollo, Matthew D Smyth, Sean M Lew, Dominic J Kizek, Aria Fallah
Publikováno v:
BMJ Open, Vol 12, Iss 4 (2022)
Introduction Vagus nerve stimulation (VNS) is a neuromodulation therapy that can reduce the seizure burden of children with medically intractable epilepsy. Despite the widespread use of VNS to treat epilepsy, there are currently no means to preoperat
Externí odkaz:
https://doaj.org/article/56588a382ae446cd828debc66ef7080d