Výsledky vyhledávání - "A G, Renwick"

The potential developmental neurotoxicity of calcium cyclamate in CD rats

Autor: Sachin Bhusari, George Pugh, Diane R. Stannard, Andrew G. Renwick, Ashley Roberts, David Myers

Publikováno v: Food and Chemical Toxicology. 153:112236

The developmental neurotoxicity of calcium cyclamate was evaluated in Sprague Dawley [Crl:CD(SD)] rats, administered in drinking water, in comparison to a concurrent control group (water) and a positive control group given propylthiouracil (PTU). Cal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d43becda4aa470a9516b2fdd6a12683
https://doi.org/10.1016/j.fct.2021.112236

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Exposure Estimation, Toxicological Requirements and Risk Assessment

Autor: Andrew G. Renwick

Publikováno v: international Food Safety handbook ISBN: 9780203750346

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d033f1a1af0a3ff6ae3e04fac6049a96
https://doi.org/10.1201/9780203750346-5

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Gut Bacteria and The Enterohepatic Circulation Of Foreign Compounds

Autor: A. G. Renwick

Publikováno v: Microbial Metabolism in the Digestive Tract ISBN: 9781351074544
Microbial Metabolism in the Digestive Tract

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fcdaee8985f635c766eb6a3fbfe1b954
https://doi.org/10.1201/9781351074544-10

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Evaluation of the Threshold of Toxicological Concern (TTC) – Challenges and approaches

Autor: I. Dewhurst, Andrew G. Renwick

Publikováno v: Regulatory Toxicology and Pharmacology. 65:168-177

Thresholds of Toxicological Concern (TTCs) have been used in the risk assessment of chemicals to which humans are exposed at very low levels. TTC values were developed using data from rodent cancer bioassays and from oral chronic and sub-chronic toxi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::945836f8df7d029cb3580ef4cbe1c089
https://doi.org/10.1016/j.yrtph.2012.03.007

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Combined Z-plasty and phalangeal fillet for reconstruction of a large carpal defect following ablative oncologic sur gery

Autor: M. Cantatore, Donald Yool, M. G. Renwick

Publikováno v: Veterinary and Comparative Orthopaedics and Traumatology. 26:510-514

SummaryA six-year-old Labrador Retriever was presented for management of a 2 x 2 cm cutaneous mass over the dorsal aspect of the carpus. A fine needle aspirate performed by the referring veterinarian was consistent with a mast cell tumour. The ipsila

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdc00c3f5b0e7c8e8d72f0853f3a6eeb
https://doi.org/10.3415/vcot-12-11-0134

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Biological fate of low-calorie sweeteners

Autor: Andrew G. Renwick, Bernadene A. Magnuson, Michael C. Carakostas, Sylvia P. Poulos, Nadia H. Moore

Publikováno v: Nutrition reviews. 74(11)

With continued efforts to find solutions to rising rates of obesity and diabetes, there is increased interest in the potential health benefits of the use of low- and no-calorie sweeteners (LNCSs). Concerns about safety often deter the use of LNCSs as

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59c0deb80dd530de6337c93d049ed75c
https://pubmed.ncbi.nlm.nih.gov/27753624

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Guidance for the Development of Chemical-Specific Adjustment Factors: Integration with Mode of Action Frameworks

Autor: Andrew G. Renwick, Bette Meek

Publikováno v: Toxicokinetics and Risk Assessment ISBN: 9780429163746

Chemical-specific adjustment factors (CSAF) provide for the incorporation of quantitative data on interspecies differences or human variability in either toxicokinetics or toxicodynamics to replace appropriately weighted components of default uncerta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0677eaa7f38c51dafda634fd35f92f5f
https://doi.org/10.1201/b14275-2

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Chemical-specific adjustment factors (inter-species toxicokinetics) to establish the ADI for steviol glycosides

Autor: Nicole Cuellar-Kingston, Alex K. Eapen, George Pugh, Rebecca Rogerson, Hua Kern, Christine M. Crincoli, Ashley Roberts, Andrew G. Renwick, Matthew Coffee, Barry Lynch, Sachin Bhusari, Sidd Purkayastha, Michael C. Carakostas

Publikováno v: Regulatory toxicology and pharmacology : RTP. 79

The acceptable daily intake (ADI) of commercially available steviol glycosides is currently 0–4 mg/kg body weight (bw)/day, based on application of a 100-fold uncertainty factor to a no-observed-adverse-effect-level value from a chronic rat study.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b9d8e8d13723746f284569fbce407ae
https://pubmed.ncbi.nlm.nih.gov/27181453

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Nanocrystalline silver dressing and subatmospheric pressure therapy following neoadjuvant radiation therapy and surgical excision of a feline injection site sarcoma

Autor: Mala G Renwick, Sally A. Argyle, Ana Marques, Samantha Woods, Donald Yool

Publikováno v: Woods, S, Marques, A, Renwick, M G, Argyle, S A & Yool, D A 2012, ' Nanocrystalline silver dressing and subatmospheric pressure therapy following neoadjuvant radiation therapy and surgical excision of a feline injection site sarcoma ', Journal of Feline Medicine and Surgery, vol. 14, no. 3, pp. 214-8 . https://doi.org/10.1177/1098612X12439269

Clinical summary This is the first clinical report of use of a combination of nanocrystalline silver and subatmospheric pressure therapy to treat a resistant wound infection, following tumour removal and radiation therapy, in a difficult-to-manage su

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2534a3d4907bfb06aecb66b0b1584fd7
https://doi.org/10.1177/1098612x12439269

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