Zobrazeno 1 - 10
of 43
pro vyhledávání: '"A G, Nikonenko"'
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Alzheimer’s disease (AD) is an incurable neurodegenerative disorder in which dysfunction and loss of synapses and neurons lead to cognitive impairment and death. Accumulation and aggregation of neurotoxic amyloid-β (Aβ) peptides generated via amy
Externí odkaz:
https://doaj.org/article/2123f68107b744559a56de68854b1867
Autor:
Christine Quentin, Veronika Lysiuk, Stephan J. Sigrist, Alexander G. Nikonenko, Martin Lehmann, Astrid G. Petzoldt, Torsten W.B. Götz, Janine Lützkendorf, Dmytro Puchkov
Publikováno v:
The Journal of Cell Biology
Presynaptic precursors deliver synaptic proteins to nascent and growing synapses. The authors provide evidence that during an early precursor formation step, the small GTPase Rab2 regulates immature precursors formation at the trans-Golgi prior to su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b605c57c71aadbaed20270488e3a9b12
https://pubmed.ncbi.nlm.nih.gov/33822845
https://pubmed.ncbi.nlm.nih.gov/33822845
Autor:
Alexander G. Nikonenko, Janine Luetzkendorf, Stephan J. Sigrist, Martin Lehmann, Torsten W. B. Goetz, Dmytro Puchkov, Astrid G. Petzoldt, Christine Quentin
SummaryReliable delivery of presynaptic material, including active zone and synaptic vesicle proteins from neuronal somata to synaptic terminals is prerequisite for faithful synaptogenesis and neurotransmission. However, molecular mechanisms controll
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28c87f8e648c83713fcabc210bc92297
https://doi.org/10.1101/2020.06.02.128991
https://doi.org/10.1101/2020.06.02.128991
Publikováno v:
Thyroid FNA Cytology ISBN: 9789811318962
The rising incidence of thyroid cancer observed after the Chernobyl accident of 1986 in Ukraine necessitates improving early diagnostics of the disease. Respective diagnostic criteria used currently in FNA cytology have a limited specificity. They us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0babe5c58aff7abbc71967dcefb74b1
https://doi.org/10.1007/978-981-13-1897-9_71
https://doi.org/10.1007/978-981-13-1897-9_71
Autor:
Giorgi Papashvili, Fang Kuang, Vladimir Sytnyk, Igor Jakovcevski, Barbara Schmalbach, Alexander G. Nikonenko, Iryna Leshchyns'ka, Eka Lepsveridze, Melitta Schachner, Nevena Djogo, Alexander Dityatev
Publikováno v:
Journal of neurochemistry 135(4), 830-844 (2015). doi:10.1111/jnc.13284
In humans, deletions/mutations in the CHL1/CALL gene are associated with mental retardation and schizophrenia. Juvenile CHL1-deficient (CHL1(-/-) ) mice have been shown to display abnormally high numbers of parvalbumin-expressing (PV(+) ) hippocampal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcf76155741b4fbff68af20625446d28
https://doi.org/10.1111/jnc.13284
https://doi.org/10.1111/jnc.13284
Publikováno v:
Cytometry Part A. 87:309-314
The nucleus of an eukaryotic cell is a membrane-bound organelle containing a major part of the cellular genome. Nuclear shape is controlled by forces generated in the cytoskeleton, nuclear envelope and matrix of the nucleus and may change when the ba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a179d1988713c4da5d7a53b6388b15e8
https://doi.org/10.1002/cyto.a.22612
https://doi.org/10.1002/cyto.a.22612
Autor:
Maria Jäpel, Christian Freund, Fabian Gerth, Franco Onofri, Volker Haucke, Fabio Benfenati, Dmytro Puchkov, Gaga Kochlamazashvili, Martin Lehmann, Tanja Maritzen, Alexander G. Nikonenko, Kristin Fredrich, Oleg Shupliakov, Arndt Pechstein
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 114(45):12057-12062
Neurotransmission is mediated by the exocytic release of neurotransmitters from readily releasable synaptic vesicles (SVs) at the active zone. To sustain neurotransmission during periods of elevated activity, release-ready vesicles need to be repleni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7787f30690c2dff4c71ff5cfc788ee60
http://hdl.handle.net/11567/889625
http://hdl.handle.net/11567/889625
Autor:
Konstantin-Alexander Hossmann, Janinne Sylvie Schmid, Günter Mies, Alexander G. Nikonenko, Zhang Ling, Christian Bernreuther, Igor Jakovcevski, Melitta Schachner
Publikováno v:
Brain Structure and Function. 218:1375-1390
Mutations in the X-chromosomal L1CAM gene lead to severe neurological deficits. In this study, we analyzed brains of female mice heterozygous for L1 (L1+/-) to gain insights into the brain structure of human females carrying one mutated L1 allele. Fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::111568b399e89d501347a714a0cde14c
https://doi.org/10.1007/s00429-012-0463-9
https://doi.org/10.1007/s00429-012-0463-9
Publikováno v:
Diagnostic Cytopathology. 40:E55-E61
Fine-needle aspiration (FNA) cytology is widely used to examine thyroid lesions. However, its diagnostic accuracy is limited by the narrow choice of cytopathologic markers indicative of invasive/metastatic powers of a tumor. The aim of this study was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a212e2670252ea13e2a9f313a654cc8
https://doi.org/10.1002/dc.21695
https://doi.org/10.1002/dc.21695
Publikováno v:
The Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology. 292:1914-1921
Cerebral ischemic injury resulting from either focal or global circulatory arrests in the brain is one of the major causes of death and disability in the adult population. The hippocampus, playing important roles in learning and memory, is selectivel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::611d0a03687bca970dd91c0d2f1ef670
https://doi.org/10.1002/ar.20969
https://doi.org/10.1002/ar.20969