Zobrazeno 1 - 10
of 80
pro vyhledávání: '"A G, Niethammer"'
Publikováno v:
Clinical pharmacology in drug developmentReferences. 11(8)
Preclinical studies in animal models of obesity and inflammation have shown that oral administration of ARD-101, a potential TAS2R agonist, reduced food intake and body weight and downregulated inflammatory cytokines. We present results from a first-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6911740b7e1fe2cee35f75081bff124
https://pubmed.ncbi.nlm.nih.gov/35509219
https://pubmed.ncbi.nlm.nih.gov/35509219
Autor:
Andreas G. Niethammer, Emilio Esteban, K. Pittman, Ho Yeong Lim, Dongrui Ray Lu, Bernard Escudier, Peggy Senico, Thomas E. Hutson, Robert J. Motzer, Subramanian Hariharan, Georg A. Bjarnason
Publikováno v:
Journal of Clinical Oncology. 32:760-767
Purpose This international phase III trial (Investigating Torisel As Second-Line Therapy [INTORSECT]) compared the efficacy of temsirolimus (mammalian target of rapamycin inhibitor) and sorafenib (vascular endothelial growth factor receptor [VEGFR] t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e29a44aa25a1874da064bd71c072e4a8
https://doi.org/10.1200/jco.2013.50.3961
https://doi.org/10.1200/jco.2013.50.3961
Autor:
K. Z’graggen, Juergen Weitz, M.W. Büchler, E. Schwab, Luis Galindo, Martina Kadmon, R. Nobiling, Andreas G. Niethammer, Ulf Hinz, Bruno M. Schmied, Friedrich H. Schmitz-Winnenthal, K. Bläuer, F. Thomas
Publikováno v:
Journal of Gastrointestinal Surgery. 13:261-268
Restorative proctocolectomy followed by an ileoanal J-pouch procedure is the therapy of choice for patients with familial adenomatous polyposis and ulcerative colitis. After low anterior rectal resection, the authors have reported on a novel, less co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb9f51ada9b8bde4c851c58fa4cd8826
https://doi.org/10.1007/s11605-008-0682-9
https://doi.org/10.1007/s11605-008-0682-9
Publikováno v:
Immunological Reviews. 222:117-128
Four novel oral DNA vaccines provide protection against melanoma, colon, breast, and lung carcinoma in mouse models. Vaccines are delivered by attenuated Salmonella typhimurium to secondary lymphoid organs and respectively target vascular endothelial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::693363ac942c16ebfd597abc774f6cc7
https://doi.org/10.1111/j.1600-065x.2008.00613.x
https://doi.org/10.1111/j.1600-065x.2008.00613.x
Autor:
Paul H.A. Quax, Gijs H.M. van Puijvelde, Paula de Vos, Johan Kuiper, Erik A.L. Biessen, Theo J.C. Van Berkel, Niels Peterse, Arnaud D. Hauer, Vincent van Weel, Ralph A. Reisfeld, Eva J.A. van Wanrooij, Andreas G. Niethammer
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 27:2050-2057
Objective— Vascular endothelial growth factor receptor 2 (VEGFR2)–overexpressing cells may form an interesting target for the treatment of atherosclerosis because of their involvement in processes that contribute to this disease, such as angiogen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81d49cac1c2bebd5004b370b04cb736f
https://doi.org/10.1161/atvbaha.107.143743
https://doi.org/10.1161/atvbaha.107.143743
Autor:
Juergen Weitz, Friedrich H. Schmitz-Winnenthal, Robert Krempien, Markus W. Büchler, M. Koch, K. Z’graggen, W. Geng, D. Rimoldi, L. V. Galindo-Escobedo, Pedro Romero, Andreas G. Niethammer, Philipp Beckhove
Publikováno v:
Cancer Letters. 252:290-298
Background To be effective and selective, immunotherapy ideally targets specifically tumor cells and spares normal tissues. Identification of tumor specific antigens is a prerequisite to establish an effective immunotherapy. Still very little is know
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::925dea9ed2349a3636a7eaa245d8c8c1
https://doi.org/10.1016/j.canlet.2007.01.003
https://doi.org/10.1016/j.canlet.2007.01.003
Autor:
Leila Sisic, Gerd Mikus, Lilli Podola, Nicolas Hohmann, Markus W. Buechler, Andreas G. Niethammer, Marco Springer, Klaus M. Breiner, Lars Grenacher, Slava Stamova, Frank Pianka, Alexis Ulrich, Simon Schimmack, Philipp Beckhove, Ruhan Koc, Markus K. Diener, Christine Leowardi, Philipp Knebel, Mariana Bucur, Thomas Schmidt, Christoph Springfeld, Heinz Lubenau, Tobias Friedrich, Walter E. Haefeli, Ulla Klaiber, Jürgen Weitz, Yingzi Ge, Anne-Valerie Keller, Friedrich H. Schmitz-Winnenthal
VEGFR-2 is expressed on tumor vasculature and a target for anti-angiogenic intervention. VXM01 is a first in kind orally applied tumor vaccine based on live, attenuated Salmonella bacteria carrying an expression plasmid, encoding VEGFR-2. We here stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1405f3b62f544e2e037da313193e2dbd
https://europepmc.org/articles/PMC4485742/
https://europepmc.org/articles/PMC4485742/
Autor:
Martina Treiber, Markus W. Büchler, Juergen Debus, Marianne Roebel, Carmen Timke, Angela Funk, Robert Krempien, Andreas G. Niethammer, Susanne Oertel, Frank W. Hensley, Falk Roeder, Marc Bischof, Angelika Zabel-du Bois, Michael J. Eble, Juergen Weitz
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 66:1143-1151
Background: We analyzed the long-term results of patients with locally advanced rectal cancer using a multimodal approach consisting of total mesorectal excision (TME), intraoperative electron-beam radiation therapy (IOERT), and pre- or postoperative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ddb90c82fc60ae662e69791d11c5c8e
https://doi.org/10.1016/j.ijrobp.2006.06.008
https://doi.org/10.1016/j.ijrobp.2006.06.008
Autor:
Angela Funk, Frank W. Hensley, Micheal J. Eble, Angelika Zahlten-Hinguranage, Jürgen Debus, Juergen Weitz, Markus W. Büchler, Martina Treiber, Ludger Bernd, Robert Krempien, Peter E. Huber, Carmen Timke, Andreas G. Niethammer, Steffen Eichin, Falk Roeder, Susanne Oertel
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 64:1416-1423
Purpose: To analyze long-term prognosis and morbidity after limb-sparing treatment of patients with extremity soft-tissue sarcoma, with intraoperative electron boost radiotherapy (IOERT) followed by a moderate dose of external beam radiotherapy (EBRT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::450a437fe5ffada4895d2f4b4c191a01
https://doi.org/10.1016/j.ijrobp.2005.10.009
https://doi.org/10.1016/j.ijrobp.2005.10.009
Autor:
Ralph A. Reisfeld, Heike Zieher, Peter E. Huber, Alexandra Roth, Juergen Debus, David W. Griggs, Amir Abdollahi, Kenneth E. Lipson, Andreas G. Niethammer, Hermann Josef Gröne, Rainer Saffrich, Dennis E. Hallahan
Publikováno v:
Clinical Cancer Research. 11:6270-6279
The involvement of αvβ3 and αvβ5 integrins in angiogenesis and the use of integrin antagonists as effective antiangiogenic agents are documented. Radiotherapy is an important therapy option for cancer. It has been shown that ionizing radiation ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cb836c001c8680ed0d8fe7d549a7b0f
https://doi.org/10.1158/1078-0432.ccr-04-1223
https://doi.org/10.1158/1078-0432.ccr-04-1223