Zobrazeno 1 - 10
of 171
pro vyhledávání: '"A G, MacLean"'
Publikováno v:
Frontiers in Aging Neuroscience, Vol 16 (2024)
IntroductionAs the population over the age of 65 increases, rates of neurodegenerative disorders and dementias will rise – necessitating further research into the cellular and molecular mechanisms that contribute to brain aging. With the critical i
Externí odkaz:
https://doaj.org/article/a63901b354be480ebbeb0947e4ed7d92
Autor:
Katie A. Hoban, BSc (Hons), MBChB, MSc, MRCS (Glasg), Samantha Downie, BMedSci (Hons), MBChB, MRCS (Ed), Douglas J.A. Adamson, MBChB, MD, PhD, FRCP (Edin), FRCR, James G. MacLean, MBChB, FRCS, FRSEd T&O, Paul Cool, MD, MMedSc(Res), DipStat, FRCS(Ed), FRCD(Orth), Arpit C. Jariwala, MS Orth, MCh Orth Dundee, MRCS Ed, FRCSEd T&O, MD
Publikováno v:
JSES International, Vol 6, Iss 4, Pp 675-681 (2022)
Hypothesis: The aim of this study was to investigate the reproducibility, reliability, and accuracy of Mirels’ score in upper limb bony metastatic disease and validate its use in predicting pathologic fractures. Methods: Forty-five patients with up
Externí odkaz:
https://doaj.org/article/5826fc9b0db54848a9189393bf601b43
Autor:
Valerie J. Pasquarella, James G. Mickley, Audrey Barker Plotkin, Richard G. MacLean, Riley M. Anderson, Leone M. Brown, David L. Wagner, Michael S. Singer, Robert Bagchi
Publikováno v:
Remote Sensing in Ecology and Conservation, Vol 7, Iss 4, Pp 592-609 (2021)
Abstract Remote sensing imagery can provide critical information on the magnitude and extent of damage caused by forest pests and pathogens. However, monitoring short‐term changes in deciduous forest condition caused by defoliating insects is chall
Externí odkaz:
https://doaj.org/article/3c2fc57a71c345e8b54fa1a15cf543a4
Autor:
Pietro Mancuso, Chen Chen, Rafal Kaminski, Jennifer Gordon, Shuren Liao, Jake A. Robinson, Mandy D. Smith, Hong Liu, Ilker K. Sariyer, Rahsan Sariyer, Tiffany A. Peterson, Martina Donadoni, Jaclyn B. Williams, Summer Siddiqui, Bruce A. Bunnell, Binhua Ling, Andrew G. MacLean, Tricia H. Burdo, Kamel Khalili
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Removal of integrated HIV DNA remains a roadblock for HIV cure. Here, Mancuso et al. show that intravenous administration of an adeno-associated virus-based CRISPR/Cas9 gene editing construct to SIV-infected macaques results in excision of integrated
Externí odkaz:
https://doaj.org/article/8cbe71bbcb2e47d19d5219446802dbe4
Autor:
Jonathan R. Holt, Mark E. Borsuk, Brett J. Butler, David B. Kittredge, Danelle Laflower, Meghan G. MacLean, Marla Markowski‐Lindsay, David Orwig, Jonathan R. Thompson
Publikováno v:
People and Nature, Vol 2, Iss 1, Pp 204-216 (2020)
Abstract Invasive forest insects can induce tree mortality in two ways: (a) by directly harming trees; or (b) by influencing forest owners to pre‐emptively harvest threatened trees. This study investigates forest owners’ intentions to harvest tre
Externí odkaz:
https://doaj.org/article/4d9f1ce66c6349c394d6d5ea602b821f
Autor:
Ryan P. McNamara, Yijun Zhou, Anthony B. Eason, Justin T. Landis, Meredith G. Chambers, Smaranda Willcox, Tiffany A. Peterson, Blake Schouest, Nicholas J. Maness, Andrew G. MacLean, Lindsey M. Costantini, Jack D. Griffith, Dirk Peter Dittmer
Publikováno v:
Journal of Extracellular Vesicles, Vol 11, Iss 3, Pp n/a-n/a (2022)
Abstract Extracellular vesicles (EVs) are secreted from all cell types and are intimately involved in tissue homeostasis. They are being explored as vaccine and gene therapy platforms, as well as potential biomarkers. As their size is below the diffr
Externí odkaz:
https://doaj.org/article/bfdb26258be341f2b7df2687fcdaa843
Autor:
Miranda D. Horn, Andrew G. MacLean
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
Extracellular vesicles (EVs) are small, membrane-bound vesicles released by cells as a means of intercellular communication. EVs transfer proteins, nucleic acids, and other biologically relevant molecules from one cell to another. In the context of v
Externí odkaz:
https://doaj.org/article/2a55f2bedab64fee9919fe61fafb4572
Autor:
Elizabeth C. Delery, Andrew G. MacLean
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
While there are murine and rat choroid plexus epithelial cell cultures, a translationally relevant model for choroid plexus activation and function is still lacking. The rhesus macaque is the gold standard for modeling viral infection and activation
Externí odkaz:
https://doaj.org/article/9892cea6324f4b25b8da6d82e87b3e0f
Publikováno v:
AIAA SCITECH 2023 Forum.
Autor:
Ryan P. McNamara, Lindsey M. Costantini, T. Alix Myers, Blake Schouest, Nicholas J. Maness, Jack D. Griffith, Blossom A. Damania, Andrew G. MacLean, Dirk P. Dittmer
Publikováno v:
mBio, Vol 9, Iss 1 (2018)
ABSTRACT Extracellular vesicles (EVs) or exosomes have been implicated in the pathophysiology of infections and cancer. The negative regulatory factor (Nef) encoded by simian immunodeficiency virus (SIV) and human immunodeficiency virus (HIV) plays a
Externí odkaz:
https://doaj.org/article/c19a962726cf4ca995b73d4cea8db3e4