Výsledky vyhledávání - "A G, Koriakova"

[Antiviral activity in vitro and pharmacokinetics of HCV entry inhibitor AVR560]

Autor: A V, Ivashchenko, P M, Iamanushkin, O D, Mit'kin, E V, Ezhova, O M, Korzinov, E A, Bulanova, A G, Koriakova, P V, Vyshemirskaia, V V, Bychko, A A, Ivashchenko

Publikováno v: Eksperimental'naia i klinicheskaia farmakologiia. 77(10)

Several novel compounds were found to be potent inhibitors of the HCV (JFH-1 isolate) infection in vitro. Human serum did not significantly reduce antiviral activity of the lead compound, AVR560 (4-fold). The immunohistochemistry studies with the Huh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c40297c81961976f6e1c9cc1bc0a8e21
https://pubmed.ncbi.nlm.nih.gov/25518527

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[Preclinical study of AV0012 early stage inhibitor of hepatitis C virus infection: I. In vitro ADME and pharmacokinetics]

Autor: A V, Ivashchenko, P M, Iamanushkin, O D, Mit'kin, E V, Ezhova, O M, Korzinov, N A, Shevkun, A G, Koriakova, R N, Karapetian, V V, Bychko, A A, Ivashchenko, V Z, Agrba, B A, Lapin, S V, Orlov

Publikováno v: Eksperimental'naia i klinicheskaia farmakologiia. 77(4)

In vitro immunohistochemical investigations on the human hepatoma cell line (Huh7) infected with hepatitis C virus (HCV) strain JFH-1 showed that AV0012 compound blocks the early stages of viral infection. AV0012 also blocked viral infection spread i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f29b1a9a6f0951f98c0ee0a50cf7892b
https://pubmed.ncbi.nlm.nih.gov/25076758

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