Zobrazeno 1 - 10
of 174
pro vyhledávání: '"A G, Hovanessian"'
Autor:
Ara G Hovanessian, Calaiselvy Soundaramourty, Diala El Khoury, Isabelle Nondier, Josette Svab, Bernard Krust
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e15787 (2010)
BACKGROUND: Nucleolin is one of the major proteins of the nucleolus, but it is also expressed on the cell surface where is serves as a binding protein for variety of ligands implicated in tumorigenesis and angiogenesis. Emerging evidence suggests tha
Externí odkaz:
https://doaj.org/article/f23d4b1362d0449b9a032539364d0786
Autor:
Damien Destouches, Diala El Khoury, Yamina Hamma-Kourbali, Bernard Krust, Patricia Albanese, Panagiotis Katsoris, Gilles Guichard, Jean Paul Briand, José Courty, Ara G Hovanessian
Publikováno v:
PLoS ONE, Vol 3, Iss 6, p e2518 (2008)
BACKGROUND: Emerging evidences suggest that nucleolin expressed on the cell surface is implicated in growth of tumor cells and angiogenesis. Nucleolin is one of the major proteins of the nucleolus, but it is also expressed on the cell surface where i
Externí odkaz:
https://doaj.org/article/1ceeda810c87460dab9905737493ffe7
Autor:
Calayselvy Soundaramourty, Bernard Krust, Rima Benferhat, Le Grand R, Ara G. Hovanessian, Jérôme Estaquier, Nathalie Dereuddre-Bosquet
Publikováno v:
Journal of Virology. 92
We have previously reported that the CBD1 peptide (SLEQIWNNMTWMQWDK), corresponding to the consensus caveolin-1 binding domain in human immunodeficiency virus type 1 (HIV-1) envelope glycoprotein gp41, elicits peptide-specific antibodies. Here, we ha
Publikováno v:
Molecular Immunology
Molecular Immunology, Elsevier, 2009, 46 (4), pp.705-12. ⟨10.1016/j.molimm.2008.10.001⟩
Molecular Immunology, 2009, 46 (4), pp.705-12. ⟨10.1016/j.molimm.2008.10.001⟩
Molecular Immunology, Elsevier, 2009, 46 (4), pp.705-12. ⟨10.1016/j.molimm.2008.10.001⟩
Molecular Immunology, 2009, 46 (4), pp.705-12. ⟨10.1016/j.molimm.2008.10.001⟩
International audience; CBD1 peptide (SLEQIWNNMTWMQWDK), corresponding to the consensus caveolin-1 binding domain in HIV-1 envelope glycoprotein gp41, elicits the production of antibodies that inhibit infection of primary CD4(+) T lymphocytes by vari
Autor:
Sylviane Muller, Stéphane Ferris, Claude Desgranges, Bernard Krust, Hayet Dali, Josette Svab, Jean Paul Briand, Ara G. Hovanessian, Elias A. Said
Publikováno v:
Immunity. 21(5):617-627
Caveolin-1 is a scaffolding protein that organizes and concentrates specific ligands within the caveolae membranes. We identified a conserved caveolin-1 binding motif in the HIV-1 transmembrane envelope glycoprotein gp41 and designed several syntheti
Publikováno v:
Experimental Cell Research. 276:155-173
The cross-linking of HIV on permissive cells results aggregation of HIV particles with surface nucleolin, CD4, and CXCR4, but without affecting the organization of CD45. In addition, HIV particles and nucleolin coaggregate with glycolipid-enriched me
Autor:
Valerie Legrand, Manuel Rosa-Calatrava, Odile Filhol, Evelyne Pichard, Sylvie Souquere-Besse, Ara G. Hovanessian, Claude Cochet, Francine Puvion-Dutilleul
Publikováno v:
Microscopy Research and Technique. 56:465-478
The effects of the adenovirus infection on the distribution of the cellular protein kinase CK2 and double-stranded RNA-activated protein kinase (PKR) were examined at the ultrastructural level. Immunogold labeling revealed the redistribution of CK2 s
Autor:
Jong Sang Ryu, Baik Ho Cho, Jang Kyung Choi, Pyung Ok Lim, Ung Lee, Ara G. Hovanessian, Cheol Soo Kim, Hong Gil Nam
Publikováno v:
Molecular Breeding. 10:11-18
We have developed a new strategy for engineering resistance to multipleviruses in plants. The strategy exploits the human double stranded (ds)RNA-dependent protein kinase (PKR). PKR is one of theinterferon-induced enzymes. It confers viral resistance
Autor:
Ara G. Hovanessian, R. Vienet, Bernard Krust, Lena Edelman, Christian Callebaut, J. M. Grognet, J. P. Briand, Etienne Jacotot, Gilles Guichard, Catherine Rougeot, A. Cardona
Publikováno v:
Proceedings of the National Academy of Sciences. 98:14090-14095
The HB-19 pseudopeptide 5[Kψ(CH 2 N)PR]-TASP, ψ(CH 2 N) for reduced peptide bond, is a specific inhibitor of HIV infection in different CD4 + cell lines and in primary T-lymphocytes and macrophages. It blocks virus-particle attachment to permissive
Publikováno v:
Virology. 281(2):248-264
The growth factor midkine (MK) has been reported to bind heparan sulfate and nucleolin, two components of the cell surface implicated in the attachment of HIV-1 particles. Here we show that synthetic and recombinant preparations of MK inhibit in a do