Zobrazeno 1 - 10
of 285
pro vyhledávání: '"A G, Gabibov"'
Autor:
Yakov A. Lomakin, Leyla A. Ovchinnikova, Stanislav S. Terekhov, Samir S. Dzhelad, Igor Yaroshevich, Ilgar Mamedov, Anastasia Smirnova, Tatiana Grigoreva, Igor E. Eliseev, Ioanna N. Filimonova, Yuliana A. Mokrushina, Victoria Abrikosova, Maria P. Rubtsova, Nikita N. Kostin, Maria A. Simonova, Tatiana V. Bobik, Natalia L. Aleshenko, Alexander I. Alekhin, Vitali M. Boitsov, Hongkai Zhang, Ivan V. Smirnov, Yuri P. Rubtsov, Alexander G. Gabibov
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-13 (2024)
Abstract Identifying high-affinity antibodies in human serum is challenging due to extremely low number of circulating B cells specific to the desired antigens. Delays caused by a lack of information on the immunogenic proteins of viral origin hamper
Externí odkaz:
https://doaj.org/article/9a1b2eaaa96441b3b3acb5378dc413ce
Autor:
Aleksandr S. Chernov, Maksim V. Rodionov, Vitaly A. Kazakov, Karina A. Ivanova, Fedor A. Meshcheryakov, Anna A. Kudriaeva, Alexander G. Gabibov, Georgii B. Telegin, Alexey A. Belogurov
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Introduction: The acute respiratory distress syndrome (ARDS), secondary to viral pneumonitis, is one of the main causes of high mortality in patients with COVID-19 (novel coronavirus disease 2019)—ongoing SARS-CoV-2 infection— reached more than 0
Externí odkaz:
https://doaj.org/article/940624a22a46463d8fc68ad8dbd01e82
Autor:
Irina A. Ishina, Inna N. Kurbatskaia, Azad E. Mamedov, Elena I. Shramova, Sergey M. Deyev, Kamila S. Nurbaeva, Yury P. Rubtsov, Alexey A. Belogurov, Alexander G. Gabibov, Maria Y. Zakharova
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2024)
The identification of low-frequency antigen-specific CD4+ T cells is crucial for effective immunomonitoring across various diseases. However, this task still encounters experimental challenges necessitating the implementation of enrichment procedures
Externí odkaz:
https://doaj.org/article/a129dec8781a47c7902bb97ebee31679
Autor:
V. M. Ukrainskaya, O. E. Musatova, D. V. Volkov, D. S. Osipova, D. S. Pershin, A. M. Moysenovich, E. G. Evtushenko, E. A. Kulakovskaya, E. G. Maksimov, H. Zhang, Y. P. Rubtsov, M. A. Maschan, A. V. Stepanov, A. G. Gabibov
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Tumor-derived extracellular vesicles (EVs) are active contributors in metastasis and immunosuppression in tumor microenvironment. At least some of the EVs carry tumor surface molecules such as tumor-associated antigens (TAAs) and/or checkpoi
Externí odkaz:
https://doaj.org/article/2cb173f3f63b4d86a4068a2d2e7d646a
Autor:
Sofiya O. Pipiya, Arsen M. Kudzhaev, Nisso Z. Mirzoeva, Yuliana A. Mokrushina, Rustam H. Ziganshin, Alexey S. Komlev, Polina E. Petrova, Ivan V. Smirnov, Alexander G. Gabibov, Olga V. Shamova, Stanislav S. Terekhov
Publikováno v:
Antibiotics, Vol 12, Iss 12, p 1719 (2023)
The global spread of antibiotic resistance marks the end of the era of conventional antibiotics. Mankind desires new molecular tools to fight pathogenic bacteria. In this regard, the development of new antimicrobials based on antimicrobial peptides (
Externí odkaz:
https://doaj.org/article/71e5d2c0b34f4525abbd3977166308a9
Autor:
Yakov A. Lomakin, Ivan V. Zvyagin, Leyla A. Ovchinnikova, Marsel R. Kabilov, Dmitriy B. Staroverov, Artem Mikelov, Alexey E. Tupikin, Maria Y. Zakharova, Nadezda A. Bykova, Vera S. Mukhina, Alexander V. Favorov, Maria Ivanova, Taras Simaniv, Yury P. Rubtsov, Dmitriy M. Chudakov, Maria N. Zakharova, Sergey N. Illarioshkin, Alexey A. Belogurov, Alexander G. Gabibov
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundB lymphocytes play a pivotal regulatory role in the development of the immune response. It was previously shown that deficiency in B regulatory cells (Bregs) or a decrease in their anti-inflammatory activity can lead to immunological dysfun
Externí odkaz:
https://doaj.org/article/d528caab928e4513a84bb21ec05cf1a7
Autor:
Yu Guo, Lisu Huang, Guangshun Zhang, Yanfeng Yao, He Zhou, Shu Shen, Bingqing Shen, Bo Li, Xin Li, Qian Zhang, Mingjie Chen, Da Chen, Jia Wu, Dan Fu, Xinxin Zeng, Mingfang Feng, Chunjiang Pi, Yuan Wang, Xingdong Zhou, Minmin Lu, Yarong Li, Yaohui Fang, Yun-Yueh Lu, Xue Hu, Shanshan Wang, Wanju Zhang, Ge Gao, Francisco Adrian, Qisheng Wang, Feng Yu, Yun Peng, Alexander G. Gabibov, Juan Min, Yuhui Wang, Heyu Huang, Alexey Stepanov, Wei Zhang, Yan Cai, Junwei Liu, Zhiming Yuan, Chen Zhang, Zhiyong Lou, Fei Deng, Hongkai Zhang, Chao Shan, Liang Schweizer, Kun Sun, Zihe Rao
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Antibodies against SARS-CoV-2 S protein can provide a treatment strategy for COVID-19. Here, Guo et al. provide the crystal structure of a SARS-CoV2 neutralizing antibody isolated from a convalescent patient and highlight the therapeutic efficacy in
Externí odkaz:
https://doaj.org/article/21135328ba984b23bc0472defd4545f7
Autor:
Irina A. Ishina, Maria Y. Zakharova, Inna N. Kurbatskaia, Azad E. Mamedov, Alexey A. Belogurov, Alexander G. Gabibov
Publikováno v:
Cells, Vol 12, Iss 2, p 314 (2023)
Antigen presentation by major histocompatibility complex class II (MHC-II) molecules is crucial for eliciting an efficient immune response by CD4+ T cells and maintaining self-antigen tolerance. Some MHC-II alleles are known to be positively or negat
Externí odkaz:
https://doaj.org/article/6fc51c7d5a7b4982881a0387e9119871
Autor:
Maria Yu. Zakharova, Alexandra A. Kuznetsova, Victoria I. Uvarova, Anastasiia D. Fomina, Liubov I. Kozlovskaya, Elena N. Kaliberda, Inna N. Kurbatskaia, Ivan V. Smirnov, Anatoly A. Bulygin, Vera D. Knorre, Olga S. Fedorova, Alexandre Varnek, Dmitry I. Osolodkin, Aydar A. Ishmukhametov, Alexey M. Egorov, Alexander G. Gabibov, Nikita A. Kuznetsov
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
The design of effective target-specific drugs for COVID-19 treatment has become an intriguing challenge for modern science. The SARS-CoV-2 main protease, Mpro, responsible for the processing of SARS-CoV-2 polyproteins and production of individual com
Externí odkaz:
https://doaj.org/article/d34b9bc2a37f410db93fca2863eda72a
Autor:
Georgii B. Telegin, Aleksandr S. Chernov, Alexey N. Minakov, Maksim V. Rodionov, Vitaly A. Kazakov, Viktor A. Palikov, Irina P. Balmasova, Dmitry S. Asyutin, Yuri M. Poluektov, Nikolay A. Konovalov, Anna A. Kudriaeva, Aldo Spallone, Alexander G. Gabibov, Alexey A. Belogurov
Publikováno v:
Biomedicines, Vol 10, Iss 10, p 2345 (2022)
Traumatic injury of the spinal cord is still one of the most challenging problems in the neurosurgical practice. Despite a long history of implementation of translational medicine in the field of spinal cord injury (SCI), it remains one of the most f
Externí odkaz:
https://doaj.org/article/c4f16d61c2ee4013a99d7c5c734d7552