Zobrazeno 1 - 10
of 145
pro vyhledávání: '"A G, Freud"'
Autor:
Leah Stein, Karthikeyan Murugesan, Julie W. Reeser, Zachary Risch, Michele R. Wing, Anoosha Paruchuri, Eric Samorodnitsky, Emily L. Hoskins, Thuy Dao, Amy Smith, Dat Le, Melissa A. Babcook, Yi Seok Chang, Matthew R. Avenarius, Muhammad Imam, Aharon G. Freud, Sameek Roychowdhury
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-7 (2024)
Abstract Genomic alterations in fibroblast growth factor receptor (FGFR) genes are present in a small number of metastatic pancreatic ductal adenocarcinomas (PDAC) and may represent an emerging subgroup of patients likely to benefit from FGFR targete
Externí odkaz:
https://doaj.org/article/a41e0b6fdf164294aff1b7579f669da5
Autor:
Courtney J. Riedinger, Caprice D. Eisele, Ashwini Esnakula, Daniel G. Stover, Aharon G. Freud, Casey M. Cosgrove
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Invasive lobular breast cancer (ILC) is characterized by a relatively high risk for late recurrence and a unique metastatic pattern with an increased risk for metastasis to gynecologic organs and peritoneum. We present a unique case of recurrent ILC
Externí odkaz:
https://doaj.org/article/cf3fbf72e97046349ada045e5ec553e8
Autor:
Zachary Risch, Benjamin H. Kaffenberger, Catherine G. Chung, Eric Samorodnitsky, Emily L. Hoskins, Thuy Dao, Amy Smith, Sarah A. Wall, Jonathan Brammer, Julie W. Reeser, Michele R. Wing, Julia F. Hopkins, Lee A. Albacker, Lynne V. Abruzzo, Caprice D. Eisele, Aharon G. Freud, Sameek Roychowdhury, Katherine E. Walsh
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
Not available.
Externí odkaz:
https://doaj.org/article/704f7687031a42c2a2cb5264cf04ea6e
Autor:
Hongchuan Li, Md Ahasanur Rahman, Michael Ruesch, Caprice D. Eisele, Erik M. Anderson, Paul W. Wright, Jennie Cao, Shashikala Ratnayake, Qingrong Chen, Chunhua Yan, Daoud Meerzaman, Roshini S. Abraham, Aharon G. Freud, Stephen K. Anderson
Publikováno v:
Cell Reports, Vol 42, Iss 11, Pp 113454- (2023)
Summary: Previous studies of the murine Ly49 and human KIR gene clusters implicated competing sense and antisense promoters in the control of variegated gene expression. In the current study, an examination of transcription factor genes defines an ab
Externí odkaz:
https://doaj.org/article/53ef519c8e7344d8ac994b0e279e76e5
Autor:
Kaitlin A. Read, Devin M. Jones, Srijana Pokhrel, Emily D. S. Hales, Aditi Varkey, Jasmine A. Tuazon, Caprice D. Eisele, Omar Abdouni, Abbey Saadey, Melissa R. Leonard, Robert T. Warren, Michael D. Powell, Jeremy M. Boss, Emily A. Hemann, Jacob S. Yount, Gang Xin, Hazem E. Ghoneim, Chan-Wang J. Lio, Aharon G. Freud, Patrick L. Collins, Kenneth J. Oestreich
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
The regulation and direction of CD4+ T cells into phenotypic and functional lineages is coordinated by a complex set of mechanisms. Here the authors show a role for Aiolos as a regulator of the CD4+ cytotoxic and T follicular helper lineages.
Externí odkaz:
https://doaj.org/article/db3616878fde4edbb2df4e62fd0817bd
Autor:
Giancarlo R. Valiente, Armin Munir, Marcia L. Hart, Perry Blough, Takuma T. Wada, Emma E. Dalan, William L. Willis, Lai-Chu Wu, Aharon G. Freud, Wael N. Jarjour
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract The gut microbiota (GM) exerts a strong influence over the host immune system and dysbiosis of this microbial community can affect the clinical phenotype in chronic inflammatory conditions. To explore the role of the GM in lupus nephritis, w
Externí odkaz:
https://doaj.org/article/3eb3b055698a4551972032c615d72505
Autor:
Benjamin Krämer, Ansel P. Nalin, Feiyang Ma, Sarah Eickhoff, Philipp Lutz, Sonia Leonardelli, Felix Goeser, Claudia Finnemann, Gudrun Hack, Jan Raabe, Michael ToVinh, Sarah Ahmad, Christoph Hoffmeister, Kim M. Kaiser, Steffen Manekeller, Vittorio Branchi, Tobias Bald, Michael Hölzel, Robert Hüneburg, Hans Dieter Nischalke, Alexander Semaan, Bettina Langhans, Dominik J. Kaczmarek, Brooke Benner, Matthew R. Lordo, Jesse Kowalski, Adam Gerhardt, Jörg Timm, Marieta Toma, Raphael Mohr, Andreas Türler, Arthur Charpentier, Tobias van Bremen, Georg Feldmann, Arne Sattler, Katja Kotsch, Ali T. Abdallah, Christian P. Strassburg, Ulrich Spengler, William E. Carson, III, Bethany L. Mundy-Bosse, Matteo Pellegrini, Timothy E. O’Sullivan, Aharon G. Freud, Jacob Nattermann
Publikováno v:
Cell Reports, Vol 42, Iss 1, Pp 111937- (2023)
Summary: Group 1 innate lymphoid cells (ILCs) comprise a heterogeneous family of cytotoxic natural killer (NK) cells and ILC1s. We identify a population of “liver-type” ILC1s with transcriptional, phenotypic, and functional features distinct from
Externí odkaz:
https://doaj.org/article/0084e5451ed64fc0b420c8bfd7ffa888
Autor:
Hui-Zi Chen, MD, PhD, Russell Bonneville, BS, Anoosha Paruchuri, PhD, Julie W. Reeser, PhD, Michele R. Wing, PhD, Eric Samorodnitsky, PhD, Melanie A. Krook, PhD, Amy M. Smith, BS, Thuy Dao, BS, Jharna Miya, MS, Walter Wang, BS, Lianbo Yu, PhD, Aharon G. Freud, MD, PhD, Patricia Allenby, MD, Sharon Cole, MD, Gregory Otterson, MD, Peter Shields, MD, David P. Carbone, MD, PhD, Sameek Roychowdhury, MD, PhD
Publikováno v:
JTO Clinical and Research Reports, Vol 2, Iss 4, Pp 100164- (2021)
Introduction: Relapsed SCLC is characterized by therapeutic resistance and high mortality rate. Despite decades of research, mechanisms responsible for therapeutic resistance have remained elusive owing to limited tissues available for molecular stud
Externí odkaz:
https://doaj.org/article/d41ee449b2bc4d2ab3b5a1f76d7484c9
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Externí odkaz:
https://doaj.org/article/e0768cc3567b4eed939d71bbf15d566e
Autor:
Bethany Mundy-Bosse, Nathan Denlinger, Eric McLaughlin, Nitin Chakravarti, Susan Hwang, Li Chen, Hsiaoyin Charlene Mao, David Kline, Youssef Youssef, Rebecca Kohnken, Dean Anthony Lee, Gerard Lozanski, Aharon G. Freud, Pierluigi Porcu, Basem William, Michael A. Caligiuri, Anjali Mishra
Publikováno v:
Blood Advances, Vol 2, Iss 15, Pp 1818-1827 (2018)
Externí odkaz:
https://doaj.org/article/8297899242c74be7b7f7999b0534700f