Zobrazeno 1 - 10
of 313
pro vyhledávání: '"A G, Basnakian"'
Autor:
Khandoker Usran Ferdous, Mulu Z. Tesfay, Aleksandra Cios, Randal S. Shelton, Conner Hartupee, Alicja Urbaniak, Jean Christopher Chamcheu, Michail N. Mavros, Emmanouil Giorgakis, Bahaa Mustafa, Camila C. Simoes, Isabelle R. Miousse, Alexei G. Basnakian, Omeed Moaven, Steven R. Post, Martin J. Cannon, Thomas Kelly, Bolni Marius Nagalo
Publikováno v:
Biomedicines, Vol 12, Iss 7, p 1596 (2024)
About one-fourth of patients with pancreatic ductal adenocarcinoma (PDAC) are categorized as borderline resectable (BR) or locally advanced (LA). Chemotherapy and radiation therapy have not yielded the anticipated outcomes in curing patients with BR/
Externí odkaz:
https://doaj.org/article/26e24818024f44df999d68d0ff29c36b
Autor:
Wenjun Wang, Jianshuang Li, Junyang Tan, Miaomiao Wang, Jing Yang, Zhi-Min Zhang, Chuanzhou Li, Alexei G. Basnakian, Hong-Wen Tang, Norbert Perrimon, Qinghua Zhou
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
The role of Endonuclease G in autophagy remains unclear. Here the authors report that ENDOG is released from mitochondria during starvation and promotes autophagy by suppressing mTOR signaling and activating DNA damage response.
Externí odkaz:
https://doaj.org/article/350ee72370584337b6076ca9cb427330
Autor:
Steven A. Chambers, Mathew Newman, Melissa M. Frangie, Alena V. Savenka, Alexei. G. Basnakian, Mohammad A. Alam
Publikováno v:
Royal Society Open Science, Vol 8, Iss 8 (2021)
The discovery of chimeric anti-melanoma agents is reported. These molecules are potent growth suppressors of melanoma cells in vitro with growth inhibition of 50% (GI50) values as low as 1.32 µM. Compounds were more toxic to melanoma cells in vitro
Externí odkaz:
https://doaj.org/article/dc7a846653dc4d9ca1a67b5f54f5b20b
Autor:
Sarita Garg, Tarun K. Garg, Isabelle R. Miousse, Stephen Y. Wise, Oluseyi O. Fatanmi, Alena V. Savenka, Alexei G. Basnakian, Vijay K. Singh, Martin Hauer-Jensen
Publikováno v:
Antioxidants, Vol 11, Iss 10, p 1895 (2022)
Exposure to high doses of radiation, accidental or therapeutic, often results in gastrointestinal (GI) injury. To date, there are no therapies available to mitigate GI injury after radiation exposure. Gamma-tocotrienol (GT3) is a promising radioprote
Externí odkaz:
https://doaj.org/article/0172642cac77426eb4f9fb4893f02c6a
Autor:
Sajedeh Rezaei Cherati, Muhammad Anas, Shijie Liu, Sudha Shanmugam, Kamal Pandey, Steven Angtuaco, Randal Shelton, Aida N. Khalfaoui, Savenka V. Alena, Erin Porter, Todd Fite, Huaixuan Cao, Micah J. Green, Alexei G. Basnakian, Mariya V. Khodakovskaya
Publikováno v:
ACS Nano. 16:12061-12072
Carbon-based nanomaterials (CBNs) are often used for potential agricultural applications. Since CBNs applied to plants can easily enter plant organs and reach the human diet, the consequences of the introduction of CBNs into the food chain need to be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad5bc5510e8c380844adbb2549c687b2
https://doi.org/10.1021/acsnano.2c02201
https://doi.org/10.1021/acsnano.2c02201
Autor:
Evan Delancey, Devin Allison, Hansa Raj KC, David F. Gilmore, Todd Fite, Alexei G. Basnakian, Mohammad A. Alam
Publikováno v:
Antibiotics, Vol 9, Iss 10, p 650 (2020)
Acinetobacter baumannii has emerged as one of the most lethal drug-resistant bacteria in recent years. We report the synthesis and antimicrobial studies of 25 new pyrazole-derived hydrazones. Some of these molecules are potent and specific inhibitors
Externí odkaz:
https://doaj.org/article/7378612825b14da4bd4e8488db5c7649
Autor:
Jedidiah Whitt, Cameron Duke, Anthony Sumlin, Steven A. Chambers, Rawan Alnufaie, David Gilmore, Todd Fite, Alexei G. Basnakian, Mohammad A. Alam
Publikováno v:
Molecules, Vol 24, Iss 11, p 2051 (2019)
Microbial resistance to drugs is an unresolved global concern, which is present in every country. Developing new antibiotics is one of the guidelines of the Centers for Disease Control and Preventions (CDC) to combat bacterial resistance to drugs. Ba
Externí odkaz:
https://doaj.org/article/a4781626114c4ff88a8c5b87164b5e93
Autor:
Sarita Garg, Ratan Sadhukhan, Sudip Banerjee, Alena V. Savenka, Alexei G. Basnakian, Victoria McHargue, Junru Wang, Snehalata A. Pawar, Sanchita P. Ghosh, Jerry Ware, Martin Hauer-Jensen, Rupak Pathak
Publikováno v:
Antioxidants, Vol 8, Iss 3, p 57 (2019)
Natural antioxidant gamma-tocotrienol (GT3), a vitamin E family member, provides intestinal radiation protection. We seek to understand whether this protection is mediated via mucosal epithelial stem cells or sub-mucosal mesenchymal immune cells. Veh
Externí odkaz:
https://doaj.org/article/cdb9da39a77b489f9f6ca23923a8c9e0
Autor:
Justin W.C. Leung, Kimberly J. Krager, Ratan Sadhukhan, Alexei G. Basnakian, Rupak Pathak, Sarthak Garg, Alena V. Savenka
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports
Scientific Reports
Kruppel-like factor 2 (KLF2) is a positive transcriptional regulator of several endothelial protective molecules, including thrombomodulin (TM), a surface receptor, and endothelial nitric oxide synthase (eNOS), an enzyme that generates nitric oxide (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de3f68655c5c96a411e0af424e18215f
http://link.springer.com/article/10.1038/s41598-020-64672-3
http://link.springer.com/article/10.1038/s41598-020-64672-3
Autor:
Sarita Garg, Tarun K. Garg, Stephen Y. Wise, Oluseyi O. Fatanmi, Isabelle R. Miousse, Alena V. Savenka, Alexei G. Basnakian, Vijay K. Singh, Martin Hauer-Jensen
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 9; Pages: 4643
The gastrointestinal (GI) system is highly susceptible to irradiation. Currently, there is no Food and Drug Administration (FDA)-approved medical countermeasures for GI radiation injury. The vitamin E analog gamma-tocotrienol (GT3) is a promising rad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::363d63a87be6580ce80625e4deda4c2c
https://pubmed.ncbi.nlm.nih.gov/35563033
https://pubmed.ncbi.nlm.nih.gov/35563033