Zobrazeno 1 - 10
of 131
pro vyhledávání: '"A F Yarrow"'
Autor:
Hui Jean Kok, Drew B. Fletcher, Jacob C. Oster, Christine F. Conover, Elisabeth R. Barton, Joshua F. Yarrow
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 15, Iss 4, Pp 1309-1323 (2024)
Abstract Background The rate and magnitude of skeletal muscle wasting after severe spinal cord injury (SCI) exceeds most other disuse conditions. Assessing the time course of molecular changes can provide insight into the progression of muscle wastin
Externí odkaz:
https://doaj.org/article/19675bbacfd3472f8c8e7856d339e21b
Autor:
E. J. Castillo, J. M. Jiron, C. S. Croft, D. G. Freehill, C. M. Castillo, J. Kura, J. F. Yarrow, I. Bhattacharyya, D. B. Kimmel, J. Ignacio Aguirre
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
Medication-related osteonecrosis of the jaw (MRONJ) is a potentially severe adverse event in patients treated with antiresorptives. Management of MRONJ is challenging, and no non-antibiotic, established medical treatment exists. Intermittent parathyr
Externí odkaz:
https://doaj.org/article/2729a8a731f34c03a64d4c10fad7e9ef
Autor:
Miles E. Cameron, Patrick W. Underwood, Iverson E. Williams, Thomas J. George, Sarah M. Judge, Joshua F. Yarrow, Jose G. Trevino, Andrew R. Judge
Publikováno v:
Cancer Medicine, Vol 11, Iss 1, Pp 50-60 (2022)
Abstract Pancreatic ductal adenocarcinoma (PDAC) is among the deadliest of all common malignancies. Treatment is difficult and often complicated by the presence of cachexia. The clinical portrait of cachexia contributes to the poor prognosis experien
Externí odkaz:
https://doaj.org/article/7670238a22ff4d2688bc8b0af8d4a791
Autor:
Zachary A. Graham, Xin-hua Liu, Lauren Harlow, Jiangping Pan, Daniella Azulai, Hesham A. Tawfeek, Russell D. Wnek, Alex J. Mattingly, William A. Bauman, Joshua F. Yarrow, Christopher P. Cardozo
Publikováno v:
Neurotrauma Reports, Vol 1, Iss 1, Pp 17-31 (2020)
Spinal cord injury (SCI) is associated with obesity and is a risk factor for type 2 diabetes mellitus (T2DM). Immobilization, muscle atrophy, obesity, and loss of sympathetic innervation to the liver are believed to contribute to risks of these abnor
Externí odkaz:
https://doaj.org/article/994cd3d0413242809a7a25ee08c61800
Autor:
Zachary A. Graham, Abigail Goldberger, Daniella Azulai, Christine F. Conover, Fan Ye, William A. Bauman, Christopher P. Cardozo, Joshua F. Yarrow
Publikováno v:
Physiological Reports, Vol 8, Iss 3, Pp n/a-n/a (2020)
Abstract To determine whether muscle disuse after a spinal cord injury (SCI) produces elevated markers of cellular senescence and induces markers of the senescence‐associated secretory phenotypes (SASPs) in paralyzed skeletal muscle. Four‐month
Externí odkaz:
https://doaj.org/article/3381b354e5b547e59c494fb0e86d9729
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 2, p 608 (2022)
Spinal cord injury (SCI) produces paralysis and a unique form of neurogenic disuse osteoporosis that dramatically increases fracture risk at the distal femur and proximal tibia. This bone loss is driven by heightened bone resorption and near-absent b
Externí odkaz:
https://doaj.org/article/a9320affb53245bf83f347dd06c7f68a
Autor:
Jared W. Skinner, Dana M. Otzel, Andrew Bowser, Daniel Nargi, Sanjay Agarwal, Mark D. Peterson, Baiming Zou, Stephen E. Borst, Joshua F. Yarrow
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 9, Iss 3, Pp 465-481 (2018)
Abstract Background Inconsistent fat‐free mass (FFM) and muscle strength responses have been reported in randomized clinical trials (RCTs) administering testosterone replacement therapy (TRT) to middle‐aged and older men. Our objective was to con
Externí odkaz:
https://doaj.org/article/b2d8c46696864915bda90951cb5ea6af
Publikováno v:
Science and Technology of Archaeological Research, Vol 3, Iss 1, Pp 100-111 (2017)
One important question with respect to past health and disease is the identification of patterns of caloric inadequacies. Given the substantial literature (animal and human) linking caloric inadequacy to reduced bone mass, microarchitectural deterior
Externí odkaz:
https://doaj.org/article/d1226b0418dd441291b7875b5e8d97fd
Autor:
Kirk P. Conrad, Ean G. Phillips, Jessica Jiron, Julie Bailes, Biswadeep Dhar, YanPeng Diao, Jose Ignacio Aguirre, Joshua F. Yarrow
Publikováno v:
Physiological Reports, Vol 7, Iss 11, Pp n/a-n/a (2019)
Abstract Bone fractures are associated with considerable morbidity and increased mortality. A major limitation to healing is lack of bone blood flow, which is impaired by physical disruption of intraskeletal and/or periosteal vasculature by the fract
Externí odkaz:
https://doaj.org/article/1aa3b06f0b1143b5ac11a2828307059e
Autor:
Ean G Phillips, Luke A Beggs, Fan Ye, Christine F Conover, Darren T Beck, Dana M Otzel, Payal Ghosh, Anna C F Bassit, Stephen E Borst, Joshua F Yarrow
Publikováno v:
PLoS ONE, Vol 13, Iss 3, p e0194440 (2018)
Sclerostin is a circulating osteocyte-derived glycoprotein that negatively regulates Wnt-signaling after binding the LRP5/LRP6 co-receptors. Pharmacologic sclerostin inhibition produces bone anabolic effects after spinal cord injury (SCI), however, t
Externí odkaz:
https://doaj.org/article/1b9b5703cd45433a8670c7492f56764a