Zobrazeno 1 - 10
of 108
pro vyhledávání: '"A F Yakimovskii"'
Autor:
S. N. Pchelina, T. S. Usenko, N. A. Bogankova, A. F. Yakimovskii, A. K. Emelyanov, T. V. Vavilova, A. L. Shvartsman
Publikováno v:
Медицинская иммунология, Vol 14, Iss 1-2, Pp 149-152 (2014)
Abstract. Progressive loss of dopaminergic neurons from substantia nigra is the major pathomorphologicasign in Parkinson’s disease (PD). Neuronal death is suggested to occur by programmed cell death (apoptosis) in PD patients, thus being involved i
Externí odkaz:
https://doaj.org/article/5554853da64c40bbacf5a76c91bd7f11
Autor:
A. F. Yakimovskii
Publikováno v:
Biology Bulletin Reviews. 9:532-542
This review presents the results of research concerning the role of zinc in neuronal membranes and synaptic processes. The development of views on zinc as an essential trace element is analyzed, from the demonstration of its catalytic, metabolic, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44682467ba0a56f127170081274dbb6c
https://doi.org/10.1134/s2079086419060094
https://doi.org/10.1134/s2079086419060094
Autor:
Аndrey F. Yakimovskii
Publikováno v:
Medical academic journal. 19:57-62
The aim of the article. The article is devoted to investigation of of zinc donator acizol influence to rat’s behavior, broken by intrastriatal injection of GABA-A receptor antagonist picrotoxin. Materials and methods. Adult male Wistar rats with av
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e430b4f2d8213d4e3d953c366cbd9c5
https://doi.org/10.17816/maj19257-62
https://doi.org/10.17816/maj19257-62
Autor:
Galina Baydakova, A E Kopytova, Irina Miliukhina, Ekatrina Fedotova, Ekaterina Yur'evna Zakharova, A. F. Yakimovskii, Mikhael Nikolaev, Sergey N. Illarioshkin, S.N. Pchelina, A. Emelyanov, A A Timofeeva, Konstantin Senkevich, O. Berkovich
Publikováno v:
Movement Disorders. 33:1325-1330
INTRODUCTION Glucocerebrosidase 1 mutations, the most common genetic contributor to Parkinson's disease (PD), have been associated with decreased glucocerebrosidase enzymatic activity in PD patients with glucocerebrosidase 1 mutations (glucocerebrosi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76b69a16c59a3482f638ba48ff78b8a9
https://doi.org/10.1002/mds.27393
https://doi.org/10.1002/mds.27393
Autor:
A F Yakimovskii, K V Zanin
Publikováno v:
Medical academic journal. 18:89-93
The aim of the article. The article is devoted to investigation of zinc donator acyzol influence to spontaneous or conditioned reflex locomotor activity of the rats. Materials and methods of research. The study was performed on adult male Wistar rats
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::996dee721d10b23b578a3a41f32431df
https://doi.org/10.17816/maj18189-93
https://doi.org/10.17816/maj18189-93
Autor:
E. Fedotova, N. Abramycheva, A. Kopytova, P. Andoskin, E.Y. Zakharova, Sergei N. Illarioshkin, L. Garaeva, A. F. Yakimovskii, D. Kulabukhova, A. Lavrinova, S.N. Pchelina, Konstantin Senkevich, G. Baydakova, T.S. Usenko, Irina Miliukhina, M.A. Nikolaev, A A Timofeeva, A. Emelyanov, E. Nuzhnyi
Publikováno v:
Neuroscience Letters. 636:70-76
Alpha-synuclein oligomerization plays a key role in the development of Parkinson’s disease (PD). Being the most common genetic contributor to PD, glucocerebrosidase 1 (GBA) mutations have been associated with decreased GBA enzymatic activity in PD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d17cd9af13fe4f608309fa46bd68954
https://doi.org/10.1016/j.neulet.2016.10.039
https://doi.org/10.1016/j.neulet.2016.10.039
Autor:
K. A. Senkevich, P. A. Andoskin, A. F. Yakimovskii, S. N. Pchelina, I. V. Miliukhina, A. K. Emel’yanov, A A Timofeeva, M. A. Nikolaev
Publikováno v:
Cell and Tissue Biology. 10:277-283
Impaired metabolism of α-synuclein (SNCA) and its aggregation are key molecular events underlying Parkinson’s disease (PD). Emerging data show that there is a connection between PD and the gene locus containing the SNCA gene. Meta-analyses have de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad8fc7d591a825efec10e12c528490e6
https://doi.org/10.1134/s1990519x16040064
https://doi.org/10.1134/s1990519x16040064
Autor:
I. Milyukhina, A. Ilves, E. Verbitskaya, L. N. Prakhova, D. Kulabukhova, A. Emelyanov, L. Garaeva, A. F. Yakimovskii, A E Kopytova, S.N. Pchelina, P. Andoskin, I. Vlasova, Konstantin Senkevich, M.A. Nikolaev, A A Timofeeva
Publikováno v:
Journal of the neurological sciences. 395
Parkinson's disease (PD) is the second most frequent neurodegenerative disorder. Impaired metabolism of alpha-synuclein (SNCA) and its aggregation are implicated in PD pathogenesis. SNCA has been identified as a highly significant genetic risk loci a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8025ecf4fa567e05d0f30f49f291036f
https://pubmed.ncbi.nlm.nih.gov/30316070
https://pubmed.ncbi.nlm.nih.gov/30316070
Autor:
A. K. Emel’yanov, S. Pchelina, T.S. Usenko, E. P. Nuzhnyi, Tatyana Boukina, A. F. Yakimovskii, E Yu Zakharova, M.A. Nikolaev, G.N. Salogub
Publikováno v:
Neuroscience Letters. 583:188-193
A link between lysosomal storage diseases (LSDs) and neurodegenerative disorders associated with accumulation of presynaptic protein alpha-synuclein has been shown. Particularly, Gaucher disease (GD) patients with a deficiency of the lysosomal enzyme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9976936433e00286346caa747a3e183a
https://doi.org/10.1016/j.neulet.2014.09.041
https://doi.org/10.1016/j.neulet.2014.09.041
Autor:
T. V. Kerko, A. F. Yakimovskii
Publikováno v:
Neuroscience and Behavioral Physiology. 44:1014-1019
Chronic experiments on rats addressed the effects of blockade of NMDA and metabotropic glutamate receptors in the neostriatum on conditioned reflex avoidance (in a shuttle box) and spontaneous (in an open field) behavior. Glutamate receptor antagonis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cafaa7bd6216c5e6988d48f5b4808066
https://doi.org/10.1007/s11055-014-0018-z
https://doi.org/10.1007/s11055-014-0018-z