Zobrazeno 1 - 10
of 187
pro vyhledávání: '"A F Stucchi"'
Autor:
C A Marzetta, Y E Savoy, A M Freeman, C A Long, J L Pettini, R E Hagar, P B Inskeep, K Davis, A F Stucchi, R J Nicolosi
Publikováno v:
Journal of Lipid Research, Vol 35, Iss 10, Pp 1829-1838 (1994)
The novel acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor CP-113,818 has been characterized in vitro against ACAT isolated from liver and intestine from a variety of species including human subjects, and in vivo in cholesterol-fed rats, hamster
Externí odkaz:
https://doaj.org/article/fcbe304672334e4689821e814c45a9af
Publikováno v:
Journal of Lipid Research, Vol 35, Iss 9, Pp 1592-1598 (1994)
We previously reported that freeze-thawing of LDL causes marked alterations in its structure and in vitro biological behavior, and that such changes can be completely abolished by the addition of sucrose to the LDL solution prior to freezing. (Rumsey
Externí odkaz:
https://doaj.org/article/cb71bc6ecdae47aa8700d706dd957128
Publikováno v:
The Journal of surgical research. 270
Background Postoperative adhesions are a potentially life-threatening complication of abdominal surgery. We previously showed that substance P (SP), acting through the neurokinin-1 receptor (NK-1R), is an important early mediator of adhesiogenesis th
Autor:
Kristen N Bushell, Susan E Leeman, Earl Gillespie, Adam C Gower, Karen L Reed, Arthur F Stucchi, James M Becker, Salomon Amar
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e25849 (2011)
Dysregulation of TNF-α in lamina propria macrophages (LPM) is a feature of inflammatory bowel diseases (IBD). LPS-Induced-TNF-Alpha-Factor (LITAF) is a transcription factor that mediates TNF-α expression. To determine whether LITAF participates in
Externí odkaz:
https://doaj.org/article/b0d9704075ac41869f71ced755a1dd7a
Autor:
Manuel D. Galvan, Daniel G. Remick, Beda Sarkar, Elizabeth G. King, Joseph P. Mizgerd, Arthur F. Stucchi, Peter A. Burke, George Kasotakis
Publikováno v:
Journal of Trauma and Acute Care Surgery. 82:758-765
BACKGROUND Histone deacetylase inhibitors (HDACI) are members of a family of epigenetic modifying agents with broad anti-inflammatory properties. These anti-inflammatory properties may have important therapeutic implications in acute respiratory dist
Publikováno v:
Shock
OBJECTIVE Substance P (SP) is a neuropeptide that contributes to a proinflammatory state by binding to the neurokinin 1 receptor (NK-1R). Limiting this interaction has been shown to attenuate the acute inflammation. Our hypothesis was that NK-1R acti
Autor:
David Stepien, Daniel G. Remick, Elizabeth R. Duffy, Juan R. Mella, Arthur F. Stucchi, Rituparna Moitra, Evan L. Chiswick
Sepsis remains a serious clinical problem despite intensive research efforts and numerous attempts to improve outcome by modifying the inflammatory response. Substance P, the principal ligand for the neurokinin-1 receptor, is a potent proinflammatory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7e8a7388471b03e986b08fc9e4fb13b
https://europepmc.org/articles/PMC5243197/
https://europepmc.org/articles/PMC5243197/
Autor:
Michael R. Cassidy, Stanley Heydrick, Joseph J. Gallant, Anthony J. Esposito, James M. Becker, Arthur F. Stucchi
Publikováno v:
Journal of Surgical Research. 181:25-31
Background The substance P (SP) or neurokinin-1 receptor pathway has been implicated in intra-abdominal adhesion formation, in large part through its effects on peritoneal fibrinolysis. This study investigates the role of SP as an early mediator of t
Autor:
Daniel I. Chu, Holly K. Sheldon, Michael R. Cassidy, Melanie L. Gainsbury, Arthur F. Stucchi, James M. Becker
Publikováno v:
Journal of Gastrointestinal Surgery. 16:325-333
While bioresorbable solid barriers such as Seprafilm® prevent adhesions, their efficacy is limited to sites of application. The aim of this study was to assess the effectiveness of the sprayable adhesion barrier Sepraspray® in preventing adhesions
Autor:
Kleanthis Dendrinos, Tai C. Chen, H. Nimitphong, A. Vijjeswarapu, Rachael M. Biancuzzo, Michael F. Holick, A. B. Boulanger, Francis A. Farraye, Arthur F. Stucchi, A. Tanennbaum
Publikováno v:
Inflammatory Bowel Diseases. 17:2116-2121
Background: Vitamin D deficiency is a common problem in patients with Crohn's disease (CD). The aim of this study was to determine the ability of normal subjects and patients with quiescent CD to absorb vitamin D2 using a novel vitamin D bioavailabil