Zobrazeno 1 - 8
of 8
pro vyhledávání: '"A F Ofulue"'
Publikováno v:
Experimental Lung Research. 20:27-40
It is yet unknown whether the impaired nutritional status of streptozotocin-induced diabetic rats influences changes in levels of insulin-like growth factor-I (IGF-I) in this experimental model of diabetes. To explore this possibility, simultaneous s
Autor:
Hassan Khadempour, Kamala Cherukupalli, Harman S. Sekhon, Anwuli F. Ofulue, William M. Thurlbeck
Publikováno v:
Pediatric Pulmonology. 10:46-51
To determine the role of calmodulin in postnatal lung growth and development, 4-week-old rats were injected intraperitoneally on consecutive days with trifluoperazine (TFP), a potent and specific calmodulin antagonist, for a period of 3 weeks and stu
Publikováno v:
The American journal of physiology. 275(6)
The aim of this study was to compare the time course of neutrophil and macrophage elastinolytic potentials in the lungs of rats exposed daily to cigarette smoke inhalation for 1–6 mo in relation to the onset and progression of cigarette smoke-induc
Publikováno v:
Clinical biochemistry. 27(1)
We have investigated whether varied assay conditions account for the conflicting reports on measured alastolytic activity of alveolar macrophages (AM) cultured in direct contact with the 3 H-elastin substrate coated onto 16-mm wells in serum-containi
Publikováno v:
Pediatric pulmonology. 15(3)
Compensatory lung growth after pneumonectomy is a well established phenomenon in young humans and experimental animals. To date, the cellular initiating and/or regulatory factor(s) responsible for this growth response have yet to be established. We h
Publikováno v:
The American review of respiratory disease. 130(6)
We administered 1 mg of purified porcine elastase per 100 g body weight intraperitoneally twice weekly to male rats during the first 4 wk of life. This altered the structure of the lungs so that the proportion of alveolar duct air (the "core" of air
Autor:
M. S. Nijjar, A. F. Ofulue
Publikováno v:
Lung. 160(6)
Streptozotocin-induced diabetes caused a depression of rat lung tissue cyclic AMP-phosphodiesterase activity. This reduced activity was evident in both the 105,000×g particulate and supernatant fractions prepared from the tissue homogenates. Total c
Autor:
A F Ofulue, M S Nijjar
Publikováno v:
The Biochemical journal. 200(3)
Adenylate cyclase activity in the rat lung membranes washed with 150 microM-EGTA was stimulated by calmodulin in the presence of 100 microM-Ca2+. The calmodulin activation of the enzyme was concentration-dependent; however, at high concentrations the