Zobrazeno 1 - 10
of 50
pro vyhledávání: '"A F Maarten, Altelaar"'
Autor:
Jun Lyu, Martin Tegelaar, Harm Post, Juan Moran Torres, Costanza Torchia, A. F. Maarten Altelaar, Robert-Jan Bleichrodt, Hans de Cock, Luis G. Lugones, Han A. B. Wösten
Publikováno v:
mBio, Vol 14, Iss 1 (2023)
ABSTRACT The fungus Aspergillus niger is among the most abundant fungi in the world and is widely used as a cell factory for protein and metabolite production. This fungus forms asexual spores called conidia that are used for dispersal. Notably, part
Externí odkaz:
https://doaj.org/article/2becf9c25ccf4444a3a7bdc3bbc2469a
Autor:
Andrew N Gray, Alexander JF Egan, Inge L van't Veer, Jolanda Verheul, Alexandre Colavin, Alexandra Koumoutsi, Jacob Biboy, A F Maarten Altelaar, Mirjam J Damen, Kerwyn Casey Huang, Jean-Pierre Simorre, Eefjan Breukink, Tanneke den Blaauwen, Athanasios Typas, Carol A Gross, Waldemar Vollmer
Publikováno v:
eLife, Vol 4 (2015)
To maintain cellular structure and integrity during division, Gram-negative bacteria must carefully coordinate constriction of a tripartite cell envelope of inner membrane, peptidoglycan (PG), and outer membrane (OM). It has remained enigmatic how th
Externí odkaz:
https://doaj.org/article/04fecc86150049b7bfec873c33e51564
Author response: Cortical anchoring of the microtubule cytoskeleton is essential for neuron polarity
Autor:
A. F. Maarten Altelaar, Stefan Wieser, Bart de Haan, Johannes Ziegler, Martin Harterink, Eric van Leen, Anna van Regteren Altena, Ellen Oudejans, Sybren Portegies, Michael Krieg, Casper C. Hoogenraad, Liu He, Ravi K. Das, Riccardo Stucchi, Robbelien Kooistra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::802154ef24d540d8e06f64e88f0f7b8b
https://doi.org/10.7554/elife.55111.sa2
https://doi.org/10.7554/elife.55111.sa2
Autor:
Ravi K. Das, Liu He, Ellen Oudejans, Sybren Portegies, Stefan Wieser, Johannes Ziegler, Anna van Regteren Altena, Riccardo Stucchi, Robbelien Kooistra, A. F. Maarten Altelaar, Casper C. Hoogenraad, Martin Harterink, Bart de Haan, Eric van Leen, Michael Krieg
Publikováno v:
bioRxiv
SUMMARYNeurons are among the most highly polarized cell types. They possess structurally and functionally different processes, axon and dendrites, to mediate information flow through the nervous system. Although it is well known that the microtubule
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06e792f633f1d82cf46c40b5263f1a7f
https://doi.org/10.1101/783837
https://doi.org/10.1101/783837
Autor:
Tessy Korthout, A. F. Maarten Altelaar, Eliza Mari Kwesi-Maliepaard, Liesbeth Hoekman, Sjoerd Hendriks, Sander Palit, Thierry Schmidlin, Heinz Jacobs, Mir Farshid Alemdehy, Jan Hermen Dannenberg, Sjoerd Klarenbeek, Fred van Leeuwen, Cesare Lancini, Tibor van Welsem, Chelsea M. McLean, Hanneke Vlaming, Thom M Molenaar
Publikováno v:
EMBO Journal, 38(14). Nature Publishing Group
The EMBO Journal
EMBO journal, 38(14):e101564. Wiley-Blackwell
The EMBO Journal
EMBO journal, 38(14):e101564. Wiley-Blackwell
DOT1L methylates histone H3K79 and is aberrantly regulated in MLL‐rearranged leukemia. Inhibitors have been developed to target DOT1L activity in leukemia, but cellular mechanisms that regulate DOT1L are still poorly understood. We have identified
Autor:
Daniel S. Peeper, Sander van Doorn, Stamatia Rontogianni, Sedef Iskit, A. F. Maarten Altelaar
Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer with very limited therapeutic options. We have recently shown that the combined inhibition of EGFR and ROCK in TNBC cells results in cell death, however, the underlying me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36539482dd4edea947002822f5e28b72
Autor:
Lodewyk F. A. Wessels, René Bernards, Lisanne de la Fonteijne, Sara Mainardi, Gianluca Maddalo, Edwin Cuppen, Albert J. R. Heck, Anna Ressa, Myrthe Jager, A. F. Maarten Altelaar, Joep de Ligt, Martin Fitzpatrick, Anirudh Prahallad, Stijn Groten, Evert Bosdriesz
Publikováno v:
Ressa, A, Bosdriesz, E, de Ligt, J, Mainardi, S, Maddalo, G, Prahallad, A, Jager, M, de la Fonteijne, L, Fitzpatrick, M, Groten, S, Altelaar, A F M, Bernards, R, Cuppen, E, Wessels, L & Heck, A J R 2018, ' A System-wide Approach to Monitor Responses to Synergistic BRAF and EGFR Inhibition in Colorectal Cancer Cells ', Molecular and Cellular Proteomics, vol. 17, no. 10, pp. 1892-1908 . https://doi.org/10.1074/mcp.RA117.000486
Molecular and Cellular Proteomics, 17(10), 1892-1908. American Society for Biochemistry and Molecular Biology Inc.
Molecular & Cellular Proteomics, 17(10), 1892. American Society for Biochemistry and Molecular Biology Inc.
Molecular and Cellular Proteomics, 17(10), 1892-1908. American Society for Biochemistry and Molecular Biology Inc.
Molecular & Cellular Proteomics, 17(10), 1892. American Society for Biochemistry and Molecular Biology Inc.
Intrinsic and/or acquired resistance represents one of the great challenges in targeted cancer therapy. A deeper understanding of the molecular biology of cancer has resulted in more efficient strategies, where one or multiple drugs are adopted in no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afb2b62d6a87d2d6f8cfd017c5019cba
https://dspace.library.uu.nl/handle/1874/377105
https://dspace.library.uu.nl/handle/1874/377105
Autor:
Riccardo, Stucchi, Gabriela, Plucińska, Jessica J A, Hummel, Eitan E, Zahavi, Irune, Guerra San Juan, Oleg, Klykov, Richard A, Scheltema, A F Maarten, Altelaar, Casper C, Hoogenraad
Publikováno v:
Cell Reports
Summary Tight regulation of neuronal transport allows for cargo binding and release at specific cellular locations. The mechanisms by which motor proteins are loaded on vesicles and how cargoes are captured at appropriate sites remain unclear. To bet
Autor:
A. F. Maarten Altelaar, Myrthe Jager, Stijn Groten, Lisanne de la Fonteijne, Lodewyk F. A. Wessels, Albert J. R. Heck, Martin Fitzpatrick, Joep de Ligt, Gianluca Maddalo, Evert Bosdriesz, Sara Mainardi, Anna Ressa, Edwin Cuppen, Anirudh Prahallad, René Bernards
Publikováno v:
SSRN Electronic Journal.
Intrinsic and/or acquired resistance represents one of the great challenges in targeted cancer therapy. A deeper understanding of the molecular biology of cancer has resulted in more efficient strategies, where one or multiple drugs are adopted in no
Autor:
A. F. Maarten Altelaar, Maartje van den Biggelaar, Charlotte A. G. H. van Gelder, Bart L. van den Eshof, Kristel Kemper, Esther H. Lips, Stamatia Rontogianni, Thierry Schmidlin, Daniel S. Peeper, Albert J. R. Heck, Kelly E. Stecker
Publikováno v:
SSRN Electronic Journal.
Protein kinases play a pivotal role in cellular communication and aberrant kinase activity has been linked to a variety of disorders. Methods to directly probe kinase activation states in cells have been lacking and until now kinase activity has main