Zobrazeno 1 - 10
of 123
pro vyhledávání: '"A F Hastings"'
Autor:
Michael Papanicolaou, Amelia L. Parker, Michelle Yam, Elysse C. Filipe, Sunny Z. Wu, Jessica L. Chitty, Kaitlin Wyllie, Emmi Tran, Ellie Mok, Audrey Nadalini, Joanna N. Skhinas, Morghan C. Lucas, David Herrmann, Max Nobis, Brooke A. Pereira, Andrew M. K. Law, Lesley Castillo, Kendelle J. Murphy, Anaiis Zaratzian, Jordan F. Hastings, David R. Croucher, Elgene Lim, Brian G. Oliver, Fatima Valdes Mora, Benjamin L. Parker, David Gallego-Ortega, Alexander Swarbrick, Sandra O’Toole, Paul Timpson, Thomas R. Cox
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-21 (2022)
The distribution and organisation of matrix molecules in the tumour stroma help shape solid tumour progression. Here they perform temporal proteomic profiling of the matrisome during breast cancer progression and show that collagen XII secreted from
Externí odkaz:
https://doaj.org/article/9576cecfa4d640e3988d0c14e35ac2b3
Autor:
Nikki L. Raftopulos, Tinashe C. Washaya, Andreas Niederprüm, Antonia Egert, Mariam F. Hakeem-Sanni, Bianca Varney, Atqiya Aishah, Mariya L. Georgieva, Ellinor Olsson, Diandra Z. dos Santos, Zeyad D. Nassar, Blake J. Cochran, Shilpa R. Nagarajan, Meghna S. Kakani, Jordan F. Hastings, David R. Croucher, Kerry-Anne Rye, Lisa M. Butler, Thomas Grewal, Andrew J. Hoy
Publikováno v:
Cancer & Metabolism, Vol 10, Iss 1, Pp 1-15 (2022)
Abstract Background Prostate cancer growth is driven by androgen receptor signaling, and advanced disease is initially treatable by depleting circulating androgens. However, prostate cancer cells inevitably adapt, resulting in disease relapse with in
Externí odkaz:
https://doaj.org/article/e83c402edc4b4083861b68170e431ea4
Autor:
Sean P. Kennedy, Jeremy Z. R. Han, Neil Portman, Max Nobis, Jordan F. Hastings, Kendelle J. Murphy, Sharissa L. Latham, Antonia L. Cadell, Dushan Miladinovic, Gabriella R. Marriott, Yolande E. I. O’Donnell, Robert F. Shearer, James T. Williams, Amaya Garcia Munoz, Thomas R. Cox, D. Neil Watkins, Darren N. Saunders, Paul Timpson, Elgene Lim, Walter Kolch, David R. Croucher
Publikováno v:
Breast Cancer Research, Vol 21, Iss 1, Pp 1-17 (2019)
Abstract Background The oncogenic receptor tyrosine kinase (RTK) ERBB2 is known to dimerize with other EGFR family members, particularly ERBB3, through which it potently activates PI3K signalling. Antibody-mediated inhibition of this ERBB2/ERBB3/PI3K
Externí odkaz:
https://doaj.org/article/63c93a219e074dd1a11996f46df83abd
Autor:
Alvaro Gonzalez Rajal, Kamila A Marzec, Rachael A McCloy, Max Nobis, Venessa Chin, Jordan F Hastings, Kaitao Lai, Marina Kennerson, William E Hughes, Vijesh Vaghjiani, Paul Timpson, Jason E Cain, D Neil Watkins, David R Croucher, Andrew Burgess
Publikováno v:
eLife, Vol 10 (2021)
We previously used a pulse-based in vitro assay to unveil targetable signalling pathways associated with innate cisplatin resistance in lung adenocarcinoma (Hastings et al., 2020). Here, we advanced this model system and identified a non-genetic mech
Externí odkaz:
https://doaj.org/article/2218265a2a26450eb03d27ef3e339032
Autor:
Jordan F Hastings, Alvaro Gonzalez Rajal, Sharissa L Latham, Jeremy ZR Han, Rachael A McCloy, Yolande EI O'Donnell, Monica Phimmachanh, Alexander D Murphy, Adnan Nagrial, Dariush Daneshvar, Venessa Chin, D Neil Watkins, Andrew Burgess, David R Croucher
Publikováno v:
eLife, Vol 9 (2020)
The identification of clinically viable strategies for overcoming resistance to platinum chemotherapy in lung adenocarcinoma has previously been hampered by inappropriately tailored in vitro assays of drug response. Therefore, using a pulse model tha
Externí odkaz:
https://doaj.org/article/6cdc2a0c965744e3b31564628d883756
Autor:
Alvaro Gonzalez-Rajal, Jordan F. Hastings, D. Neil Watkins, David R. Croucher, Andrew Burgess
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Externí odkaz:
https://doaj.org/article/1ae674bac8f84f27a5762ea449544a20
Autor:
Michal Mos, Paul R. H. Robson, Sam Buckby, Astley F. Hastings, Waldemar Helios, Anna Jama-Rodzeńska, Andrzej Kotecki, Dorota Kalembasa, Stanisław Kalembasa, Marcin Kozak, Kazimierz Chmura, Magdalena Serafin-Andrzejewska, John Clifton-Brown
Publikováno v:
Agronomy, Vol 11, Iss 8, p 1679 (2021)
Biomass from M. × giganteus has great promise for use within the bioeconomy sectors, but to maximise environmental benefits, crops must produce high yields while minimising energetically costly inputs. Complex interactions between soil conditions, c
Externí odkaz:
https://doaj.org/article/f4c1c84789ab4622879ab7db2190da50
Autor:
Jordan F. Hastings, Sharissa L. Latham, Alvin Kamili, Madeleine S. Wheatley, Jeremy Z. R. Han, Marie Wong-Erasmus, Monica Phimmachanh, Max Nobis, Chiara Pantarelli, Antonia L. Cadell, Yolande E. I. O’Donnell, King Ho Leong, Sophie Lynn, Fan-Suo Geng, Lujing Cui, Sabrina Yan, Joanna Achinger-Kawecka, Clare Stirzaker, Murray D. Norris, Michelle Haber, Toby N. Trahair, Frank Speleman, Katleen De Preter, Mark J. Cowley, Ozren Bogdanovic, Paul Timpson, Thomas R. Cox, Walter Kolch, Jamie I. Fletcher, Dirk Fey, David R. Croucher
Publikováno v:
SCIENCE ADVANCES
Gene expression noise is known to promote stochastic drug resistance through the elevated expression of individual genes in rare cancer cells. However, we now demonstrate that chemoresistant neuroblastoma cells emerge at a much higher frequency when
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c49f49836711aef2f34b98a0e86d38d
https://doi.org/10.1126/sciadv.abp8314
https://doi.org/10.1126/sciadv.abp8314
Publikováno v:
Familycommunity health. 45(4)
As the United States grapples with social injustices, greater attention is being placed on the historical lack of equity practices among health and social service organizations that serve marginalized and predominantly racially minoritized communitie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ca5914edafb0d1a3661563d64dc88d7
https://pubmed.ncbi.nlm.nih.gov/35985021
https://pubmed.ncbi.nlm.nih.gov/35985021
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 4 (2016)
Each member of the epidermal growth factor receptor (EGFR) family plays a key role in normal development, homeostasis and a variety of pathophysiological conditions, most notably in cancer. According to the prevailing dogma, these four receptor tyros
Externí odkaz:
https://doaj.org/article/59e3de45ef644a72b14f4862e42c7e5e