Cardiometabolic Differences in People Living with HIV Receiving Integrase Strand Transfer Inhibitors Compared to Non-nucleoside Reverse Transcriptase Inhibitors: Implications for Current ART Strategies

Autor: Wilhelm A. J. W. Vos, Nadira Vadaq, Vasiliki Matzaraki, Twan Otten, Albert L. Groenendijk, Marc J. T. Blaauw, Louise E. van Eekeren, Kees Brinkman, Quirijn de Mast, Niels P. Riksen, Anton F. H. Stalenhoef, Jan van Lunzen, Andre J. A. M. van der Ven, Willem L. Blok, Janneke E. Stalenhoef

Publikováno v: Viruses, Vol 16, Iss 4, p 582 (2024)

In people living with HIV (PLHIV), integrase strand transfer inhibitors (INSTIs) are part of the first-line combination antiretroviral therapy (cART), while non-nucleoside reverse transcriptase inhibitor (NNRTI)-based regimens are alternatives. Disti

Externí odkaz: https://doaj.org/article/f709bcd454a146f98691dffd7cf32341

Homozygous autosomal dominant hypercholesterolaemia in the Netherlands: prevalence, genotype-phenotype relationship, and clinical outcome

Autor: Joost Besseling, G. Kees Hovingh, Barbara Sjouke, Anton F. H. Stalenhoef, Albert Wiegman, Sigrid W. Fouchier, Joep C. Defesche, John J.P. Kastelein, Jeanine E. Roeters van Lennep, D. M. Kusters, Jacqueline de Graaf, Eric J.G. Sijbrands, Iris Kindt

Publikováno v: European Heart Journal, 36, 560-5
European Heart Journal, 36, 9, pp. 560-5
European Heart Journal, 36(9), 560-565. Oxford University Press
European heart journal, 36(9), 560-565. Oxford University Press

Item does not contain fulltext AIMS: Homozygous autosomal dominant hypercholesterolaemia (hoADH), an orphan disease caused by mutations in low-density lipoprotein receptor (LDLR), apolipoprotein B (APOB), or proprotein convertase subtilisin-kexin typ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8848db858fac15b39f105ddfe337f0d5
https://hdl.handle.net/2066/152999

Familial hypercholesterolaemia is underdiagnosed and undertreated in the general population: guidance for clinicians to prevent coronary heart disease: Consensus Statement of the European Atherosclerosis Society

Autor: Anne Tybjærg-Hansen, Robert A. Hegele, Klaus G. Parhofer, Steve E. Humphries, Olov Wiklund, Alberico L. Catapano, Børge G. Nordestgaard, Joep C. Defesche, Petri T. Kovanen, Gerald F. Watts, Olivier S. Descamps, Anton F. H. Stalenhoef, P. Pajukanta, Albert Wiegman, Luis Masana, M. John Chapman, G. Kees Hovingh, Erik S.G. Stroes, Marja-Riitta Taskinen, Henry N. Ginsberg, Frederick J. Raal, Jan Albert Kuivenhoven, Jan Borén, Raul D. Santos, Kausik K. Ray, Eric Bruckert, Catherine Boileau, Maurizio Averna

Publikováno v: European Heart Journal, 34(45), 3478-90a. Oxford University Press
European Heart Journal, 34, 3478-90
European Heart Journal, 34, 45, pp. 3478-90
European heart journal, 34(45), 3478-390a. Oxford University Press

AIMS: The first aim was to critically evaluate the extent to which familial hypercholesterolaemia (FH) is underdiagnosed and undertreated. The second aim was to provide guidance for screening and treatment of FH, in order to prevent coronary heart di

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3261b5f4250aa8b300e69f131008969
https://doi.org/10.1093/eurheartj/eht273

Reducing cardiac after-load by lowering blood viscosity in patients with familial hypercholesterolemia – A pilot study. Possible mechanism for occurrence of anemia in chronic heart failure patients?

Autor: Anton F. H. Stalenhoef, Menko-Jan de Boer, Gheorghe Pop

Publikováno v: Cor et Vasa, 58, e374-e378
Cor et Vasa, 58, pp. e374-e378

Anemia is present in more than 40% of the patients with chronic heart failure (CHF), especially in those with reduced ejection fraction. The etiology is not yet understood. Hematocrit is a major determinant of whole blood viscosity, which is an impor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19ccb030e0db75950d42adf008a36b55
https://doi.org/10.1016/j.crvasa.2015.10.001

Oxidized LDL enhances pro-inflammatory responses of alternatively activated M2 macrophages: A crucial role for Krüppel-like factor 2

Autor: L.J.H. van Tits, Anton F. H. Stalenhoef, Rinke Stienstra, Leo A. B. Joosten, Mihai G. Netea, P.L.E.M. van Lent

Publikováno v: Atherosclerosis, 214, 2, pp. 345-9
Atherosclerosis, 214, 345-9

Contains fulltext : 97193.pdf (Publisher’s version ) (Closed access) OBJECTIVE: Macrophages are key players in atherogenesis because of their properties to form foam cells that produce a large variety of pro-inflammatory mediators. We addressed the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cf11c4e961630b16d0e553f55607c4e
https://doi.org/10.1016/j.atherosclerosis.2010.11.018