Zobrazeno 1 - 10
of 26
pro vyhledávání: '"A F A M, Schobben"'
Autor:
Diana A van Riet-Nales, Erwin G A W Römkens, Agnes Saint-Raymond, Piotr Kozarewicz, Alfred F A M Schobben, Toine C G Egberts, Carin M A Rademaker
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e98348 (2014)
INTRODUCTION: Pharmaceutical industry is no longer allowed to develop new medicines for use in adults only, as the 2007 Paediatric Regulation requires children to be considered also. The plans for such paediatric development called Paediatric Investi
Externí odkaz:
https://doaj.org/article/aede4028ddd948ac861abdb10be01b24
Publikováno v:
Journal of Neurology. 260:2865-2875
A common problem in brain and abdominal surgery is the perioperative substitution of antiepileptic drugs (AEDs) when patients are temporarily unable to take these drugs orally. We searched the literature for clinical trials with patients or healthy v
Autor:
Alfred F. A. M. Schobben, José A Ferreira, Barbara J de Neef, Catharine M A Rademaker, Diana A. van Riet-Nales, Toine C. G. Egberts
Publikováno v:
Archives of Disease in Childhood
Objective Liquid medicines are easy to swallow. However, they may have disadvantages, such as a bad taste or refrigerated storage conditions. These disadvantages may be avoided by the use of oral solid medicines, such as powders or tablets. The aim o
Publikováno v:
Nederlands tijdschrift voor geneeskunde. 160
A patient suffering from Zollinger-Ellison was treated with Nexium, but after patent expiry only the costs of generic omeprazol were reimbursed. Generic tablets and capsules, pantoprazol and rabeprazol, were tried without success and finally the phar
Autor:
Toine C. G. Egberts, Diana A. van Riet-Nales, Carin M. A. Rademaker, Alfred F. A. M. Schobben, Karin E. de Jager
Publikováno v:
British Journal of Clinical Pharmacology. 72:465-473
WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT • Children are entitled to safe, efficacious, child and parent friendly (i.e. age-appropriate) medicines. However, off-label and unlicensed paediatric prescription rates in hospital range from 36% (surgical
Autor:
Carin M. A. Rademaker, Alfred F. A. M. Schobben, Diana A. van Riet-Nales, Toine C. G. Egberts
Publikováno v:
Clinical Therapeutics. 32:924-938
In view of the high rates of off-label and unlicensed prescribing of drugs in children, the US Food and Drug Administration and the European Union have implemented legislative regulations for the pharmaceutical industry to increase the number of drug
Effect of Cytochrome P450 2D6 Genotype on Maternal Paroxetine Plasma Concentrations during Pregnancy
Autor:
Petra Zwarts, Toine C. G. Egberts, F. F. Tessa Ververs, Heronimus A. M. Voorbij, Svetlana V. Belitser, Gerard H. A. Visser, Alfred F. A. M. Schobben
Publikováno v:
Clinical Pharmacokinetics. 48:677-683
Increasing numbers of women in childbearing years are treated with antidepressants. Concerns regarding fetal exposure to medication has led to large studies on drug effects on birth outcome and on the risk of congenital anomalies. The risk of adverse
Autor:
Alfred F. A. M. Schobben, Maarten J. ten Berg, Albert Huisman, Patricia M. L. A. van den Bemt, Toine C. G. Egberts, Wouter W. van Solinge
Publikováno v:
Annals of Pharmacotherapy, 43(9), 1405-1412. SAGE Publishing
Background:Summaries of product characteristics (SPCs) and clinical guideline recommendations are available for monitoring the platelet count for heparin-induced thrombocytopenia (HIT) in patients receiving low-molecular-weight heparin (LMWH). Testin
Autor:
Patrick C. Souverein, Paul A. F. Jansen, Rob J. van Marum, Antoine C. G. Egberts, Alfred F. A. M. Schobben, Wilma Knol
Publikováno v:
Journal of the American Geriatrics Society. 56:661-666
OBJECTIVES: To investigate the association between antipsychotic drug use and risk of pneumonia in elderly people. DESIGN: A nested case-control analysis. SETTING: Data were used from the PHARMO database, which collates information from community pha
Autor:
Catherine M. A. Rademaker, William L. M. Kramer, Alfred F. A. M. Schobben, Aalt Van Dijk, Esther Uijtendaal, André Fleer, Jan L. L. Kimpen, Adrianus J. van Vught
Publikováno v:
Therapeutic Drug Monitoring. 23:506-513
In this prospective randomized trial, the efficacy and safety of once-daily administration of gentamicin were compared with multiple-daily administration in infants and children. In addition, pharmacokinetic variables were calculated. Gentamicin ther