Zobrazeno 1 - 10
of 99
pro vyhledávání: '"A F, ZUNINO"'
Publikováno v:
Mini-Reviews in Medicinal Chemistry. 8:856-868
Small molecules targeting p53 represent an emerging group of potentially useful agents for the improvement of antitumor therapy. These modulators include agents that activate wild-type p53 or reactivate mutant p53 and inhibitors of p53 functions. Pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f87d140005ef242411bd63f31998682
https://doi.org/10.2174/138955708785132774
https://doi.org/10.2174/138955708785132774
Autor:
N. Carenini, Pietro Apostoli, Paola Perego, S. Arandjelovic, Siniša Radulović, Laura Gatti, F. Zunino, Zivoslav Tesic, Roberto Leone
Publikováno v:
Medicinal Chemistry. 2:227-237
The aim of this study was to investigate cellular response to several ruthenium(III), chromium(III) and rhodium(III) compounds carrying bidentate beta-diketonato ligands: [(acac)--acetylacetonate ligand, (tfac)--trifluoroacetylacetonate ligand]. Cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c16726adcb48fc5fc9cdeb4e21019320
https://doi.org/10.2174/157340606776930718
https://doi.org/10.2174/157340606776930718
Publikováno v:
Cellular and Molecular Life Sciences (CMLS). 61:973-981
We used cDNA arrays to monitor modulation of mRNA expression after exposure to a multinuclear platinum complex (BBR3464) in a human cervix squamous cell carcinoma cell line (A431) and in a cisplatin-resistant subline (A431/Pt) exhibiting collateral s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f284286358cb87a30b637e80b5491b63
https://doi.org/10.1007/s00018-003-4024-5
https://doi.org/10.1007/s00018-003-4024-5
Autor:
Giovanna Petrangolini, Sara Belluco, F. Zunino, Monica Tortoreto, Rosanna Supino, Enrica Favini, Cinzia Lanzi, Giuliana Cassinelli, G Pratesi
Publikováno v:
British Journal of Cancer
IDN 5390 is a novel C-seco taxane analogue selected for preclinical development on the basis of its antimotility activity on endothelial cells, antitumour efficacy in a large panel of human tumour xenografts and high tolerability in mouse. On the bas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33b1bc404502a8d51913d6a295a94cb4
https://doi.org/10.1038/sj.bjc.6601730
https://doi.org/10.1038/sj.bjc.6601730
Publikováno v:
Current Cancer Drug Targets. 3:21-29
Although cisplatin is effective in the treatment of different types of tumors, resistance to treatment is a major limitation. In an attempt of overcoming resistance mechanisms, a large effort has been made to generate compounds with a different geome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68828a1a9750b135c949e62fae71e705
https://doi.org/10.2174/1568009033333727
https://doi.org/10.2174/1568009033333727
The naturally occurring coumarins and resveratrol, attract great attention due to their wide range of bio- logical properties, including anticancer, antileukemic, antibacterial and anti-inflammatory activities; moreover, their cancer chemopreventive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______4094::adb10a6348402c6994f5533c810ab2f8
http://hdl.handle.net/11585/90286
http://hdl.handle.net/11585/90286
Autor:
J. San Sebastián Sauto, Carmen López, M. Hidalgo García, R. Hierro Rodríguez, B. Valle Vila, L. Loyola, F. Zunino
Publikováno v:
RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
instname
instname
[EN] In 2014 FAO ordered Tragsatec the design and development of a decision making tool for locating potential areas to be put under irrigation in Argentina. During the first phase, there was a proposal of some goals and indicators based on the susta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a4da30a92d1a0dabda742f9fe73822b
http://hdl.handle.net/10251/91291
http://hdl.handle.net/10251/91291
Autor:
S. CAVANI, M. MALACARNE, G. ZEREGA, L. STAGNI, CM CAVALLINI, M. MOGNI, M. CASTAGNETTA, F. ZUNINO, A. CAPPUCCI, A. BARBONCINI, G. PIOMBO, F. DAGNA BRICARELLI, M. PIERLUIGI, PICCIONE, Maria, CORSELLO, Giovanni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3658::cd7ede41636b61f998d826769b15a4a9
http://hdl.handle.net/10447/12039
http://hdl.handle.net/10447/12039
Publikováno v:
Scopus-Elsevier
ST1926 is a novel related adamantyl retinoid endowed with potent antiproliferative and apoptogenic activity. The drug induced an early G1/S cell cycle arrest which was associated with a typical DNA damage response including modulation of genes involv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b1143e48346ec5af5afa493c5f13155
https://doi.org/10.1179/joc.2004.16.supplement-1.74
https://doi.org/10.1179/joc.2004.16.supplement-1.74
Publikováno v:
Current medicinal chemistry. 17(15)
The targeting of specific DNA repair mechanisms may be a promising strategy to improve the efficacy of antitumor therapy. The cytotoxic effects of the clinically relevant topoisomerase 1 (Top1) poison camptothecins are related to the generation of DN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3a32782b9fa6699b56d0eb84b54794f
https://pubmed.ncbi.nlm.nih.gov/20166932
https://pubmed.ncbi.nlm.nih.gov/20166932