Zobrazeno 1 - 10
of 162
pro vyhledávání: '"A F, Sadikot"'
Autor:
Gabriela Kennedy, Daryan Chitsaz, Jeanne F. Madranges, Melissa Peştemalciyan, Abbas F. Sadikot, Timothy E. Kennedy
Publikováno v:
MethodsX, Vol 11, Iss , Pp 102256- (2023)
A widespread protocol to seal coverslips on a microscope slide for histological analysis utilizes air-drying nail polish. Nail polish is applied to glue the coverslip in place and prevent the leakage of mounting media. Air drying takes time, typicall
Externí odkaz:
https://doaj.org/article/ac00b972d0124d3ba7108efd1b6d41a3
Autor:
Qing Wang, Meshal Aljassar, Nikhil Bhagwat, Yashar Zeighami, Alan C. Evans, Alain Dagher, G. Bruce Pike, Abbas F. Sadikot, Jean-Baptiste Poline
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Essential tremor (ET) is the most prevalent movement disorder with poorly understood etiology. Some neuroimaging studies report cerebellar involvement whereas others do not. This discrepancy may stem from underpowered studies, differences in
Externí odkaz:
https://doaj.org/article/5ab3e9d54e7e4c2a9f8df051385a7ce6
Autor:
Etienne Gauthier-Lafreniere, Meshal Aljassar, Vladimir V. Rymar, John Milton, Abbas F. Sadikot
Publikováno v:
Frontiers in Neuroinformatics, Vol 16 (2022)
BackgroundOrdinal scales based on qualitative observation are the mainstay in the clinical assessment of tremor, but are limited by inter-rater reliability, measurement precision, range, and ceiling effects. Quantitative tremor evaluation is well-dev
Externí odkaz:
https://doaj.org/article/9008ae253994429da16b31f1e12c986d
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-19 (2020)
Abstract Huntington’s disease (HD) is an autosomal dominant trinucleotide repeat disorder characterized by choreiform movements, dystonia and striatal neuronal loss. Amongst multiple cellular processes, abnormal neurotransmitter signalling and decr
Externí odkaz:
https://doaj.org/article/179f6ff7cfc84881a12e199ce94b16b0
Autor:
Kirsten S. Anderson, Nathalie Gosselin, Abbas F. Sadikot, Maude Laguë-Beauvais, Esther S. H. Kang, Alexandra E. Fogarty, Judith Marcoux, Jehane Dagher, Elaine de Guise
Publikováno v:
Brain Sciences, Vol 11, Iss 9, p 1173 (2021)
Music perception deficits are common following acquired brain injury due to stroke, epilepsy surgeries, and aneurysmal clipping. Few studies have examined these deficits following traumatic brain injury (TBI), resulting in an under-diagnosis in this
Externí odkaz:
https://doaj.org/article/cbb6ace1be9c4bfba66d02db7eefb604
Publikováno v:
Neurobiology of Disease, Vol 85, Iss , Pp 49-59 (2016)
This paper presents a novel model of tremor in Parkinson's disease (PD) based on extensive literature review as well as novel results stemming from functional stereotactic neurosurgery for the alleviation of tremor in PD. Specifically, evidence that
Externí odkaz:
https://doaj.org/article/5bca5afbebc6487da48f994fcad37efe
Autor:
Bruce G. Pike, Justyna R. Sarna, Yamile Jasaui, Conrad P. Rockel, Tamara Pringsheim, Abbas F. Sadikot, Rachel E. Sondergaard, Filomeno Cortese, Oury Monchi, Davide Martino
Publikováno v:
Movement Disorders. 36:2192-2198
Background The dentatorubrothalamic tract (DRTT) remains understudied in idiopathic cervical dystonia (CD), despite evidence that the pathway is relevant in the pathophysiology of the disorder. Objective The aim of this study was to examine the DRTT
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 10 (2016)
The principal projection neurons of the striatum are critically dependent on an afferent supply of brain derived neurotrophic factor (BDNF) for neurotrophic support. These neurons express TrkB, the cognate receptor for BDNF, which activates signaling
Externí odkaz:
https://doaj.org/article/cc0f627b75df45a9a0c0be0eb7663a6b
Autor:
Erin K. O'Ferrall, Vladimir V. Rymar, Abbas F. Sadikot, Bernard Brais, Marie Josée Dicaire, Rebecca Robertson, Robert J. Bryson-Richardson, Talita C. Conte, Jason C. Young, Josée N. Lavoie
Publikováno v:
The American Journal of Pathology. 190:554-562
BCL-2-associated athanogene 3 (BAG3) is a co-chaperone to heat shock proteins important in degrading misfolded proteins through chaperone-assisted selective autophagy. The recurrent dominant BAG3-P209L mutation results in a severe childhood-onset myo
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
Scientific Reports
The ability to inhibit an inappropriate action in a context is an important part of the human cognitive repertoire, and deficiencies in this ability are common in neurological and psychiatric disorders. An anti-saccade is a simple experimental task w