Zobrazeno 1 - 10
of 40
pro vyhledávání: '"A F, Fuciarelli"'
Autor:
Suramya Waidyanatha, Alfred F Fuciarelli, Steven W. Graves, S. Peter Hong, Cynthia S. Smith, Derrick J. Bates, Jerry D. Johnson
Publikováno v:
Xenobiotica. 43:1010-1017
1. Isoeugenol (IEG) has been tested for toxicity and carcinogenicity due to high potential for human exposure and the structural resemblance to known carcinogenic allylbenzenes. In order to support the interpretation of toxicity and carcinogenecity s
Autor:
Cynthia S. Smith, Derrick J. Bates, Suramya Waidyanatha, Jerry D. Johnson, Alfred F Fuciarelli, Steven W. Graves, S. Peter Hong
Publikováno v:
Xenobiotica. 43:293-302
1. Methyleugenol (MEG) has been used as a flavouring agent in food, as a fragrance in cosmetic products, and as an insect attractant. MEG was carcinogenic in both rats and mice following gavage administration. In this study we investigated plasma tox
Autor:
Bobbie-Jo M. Webb-Robertson, Kristin H. Jarman, K. Monica Lee, Sam J. Harbo, David F. Lowry, Alfred F. Fuciarelli, Q. Ryan Meng, Joel G. Pounds
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 39:830-836
Metabonomics involves the quantitation of the dynamic multivariate metabolic response of an organism to a pathological event or genetic modification [J.K. Nicholson, J.C. Lindon, E. Holmes, Xenobiotica 29 (1999) 1181-1189]. The analysis of these data
Autor:
Rodney A. Miller, Jeffrey A. Dill, Joseph H. Roycroft, Roger A. Renne, Leo T. Burka, Alfred F. Fuciarelli, Po C. Chan, Kathy M. Gideon, Kyeonghee Monica Lee
Publikováno v:
Toxicological Sciences. 72:223-234
Decalin (decahydronaphthalene) is a widely used industrial solvent known to cause male rat-specific alpha2u-globulin nephropathy. In this project, 13-week and two-year inhalation studies of decalin were conducted consecutively in both sexes of F344/N
Autor:
Yan Mao, Ronald J. Moore, Judy T. Pierce, Kathryn H. Debban, Kenneth B. Wagnon, Alfred F. Fuciarelli, Cynthia S. Smith, Jeffrey A. Dill
Publikováno v:
Chemical Research in Toxicology. 11:953-961
A quantitative method was developed for determination of alpha2u-globulin in urine and kidney samples collected from male rats using liquid chromatography-electrospray ionization mass spectrometry (LC-ESI/MS). Samples prepared from urine and kidney h
Autor:
Zhongxi Zhao, Jon H. Wahl, Alfred F. Fuciarelli, Richard D. Smith, Harold R. Udseth, Steven A. Hofstadler
Publikováno v:
Electrophoresis. 16:389-395
Capillary zone electrophoresis (CZE) and reversed anionic capillary isotachophoresis (CITP) conditions have been developed for the separation of mixtures comprised of monophosphate nucleosides, pyridine and flavin dinucleotides, and monophosphate din
Publikováno v:
Nucleic Acids Research. 23:515-521
Formation of intramolecular cross links by addition of C(5') deoxyribose radicals to the C(8)-N(7) double bond of an attached adenine base was analyzed by ab initio quantum-chemical methods. Conformational preferences that influence the stereospecifi
Autor:
S Peter, Hong, Alfred F, Fuciarelli, Jerry D, Johnson, Steven W, Graves, Derrick J, Bates, Suramya, Waidyanatha, Cynthia S, Smith
Publikováno v:
Xenobiotica; the fate of foreign compounds in biological systems. 43(3)
1. Methyleugenol (MEG) has been used as a flavouring agent in food, as a fragrance in cosmetic products, and as an insect attractant. MEG was carcinogenic in both rats and mice following gavage administration. In this study we investigated plasma tox
Yields of Radiation-induced Base Products in DNA: Effects of DNA Conformation and Gassing Conditions
Publikováno v:
International Journal of Radiation Biology. 58:397-415
Gas chromatography-mass spectrometry with selected-ion monitoring was used to measure the yields of radiation-induced base products in aqueous solutions of native or heat-denatured DNA irradiated in the dose range 20-100 Gy. These DNA solutions were
Publikováno v:
Inhalation toxicology. 16(10)
Pulmonary emphysema is a major component of the morbidity and mortality of chronic obstructive pulmonary disease (COPD). Currently there are no predictive biomarkers for COPD. Initial steps toward identifying potentially predictive biomarkers involve