Zobrazeno 1 - 10
of 564
pro vyhledávání: '"A F, Dominiczak"'
Autor:
Maeregu Woldeyes Arisido, Luisa Foco, Robin Shoemaker, Roberto Melotti, Christian Delles, Martin Gögele, Stefano Barolo, Stephanie Baron, Michel Azizi, Anna F. Dominiczak, Maria-Christina Zennaro, Peter P. Pramstaller, Marko Poglitsch, Cristian Pattaro
Publikováno v:
BMC Medical Research Methodology, Vol 23, Iss 1, Pp 1-10 (2023)
Abstract Background The recent progress in molecular biology generates an increasing interest in investigating molecular biomarkers as markers of response to treatments. The present work is motivated by a study, where the objective was to explore the
Externí odkaz:
https://doaj.org/article/2d40371db71545b3b5a59aea5a0e9586
Publikováno v:
Cambridge Prisms: Precision Medicine, Vol 1 (2023)
Precision medicine envisages the integration of an individual’s clinical and biological features obtained from laboratory tests, imaging, high-throughput omics and health records, to drive a personalised approach to diagnosis and treatment with a h
Externí odkaz:
https://doaj.org/article/79bd9f9db9d5437fab50cef277c65f9a
Autor:
Anna F Dominiczak, Sandosh Padmanabhan, Mark Caulfield, Ken Sutherland, Jiguang Wang, Jessica K Jones
Publikováno v:
Cambridge Prisms: Precision Medicine, Vol 1 (2023)
Externí odkaz:
https://doaj.org/article/3b718513e3c7412da5e863629bd32b0b
Autor:
Valgerdur Steinthorsdottir, Ralph McGinnis, Nicholas O. Williams, Lilja Stefansdottir, Gudmar Thorleifsson, Scott Shooter, João Fadista, Jon K. Sigurdsson, Kirsi M. Auro, Galina Berezina, Maria-Carolina Borges, Suzannah Bumpstead, Jonas Bybjerg-Grauholm, Irina Colgiu, Vivien A. Dolby, Frank Dudbridge, Stephanie M. Engel, Christopher S. Franklin, Michael L. Frigge, Yr Frisbaek, Reynir T. Geirsson, Frank Geller, Solveig Gretarsdottir, Daniel F. Gudbjartsson, Quaker Harmon, David Michael Hougaard, Tatyana Hegay, Anna Helgadottir, Sigrun Hjartardottir, Tiina Jääskeläinen, Hrefna Johannsdottir, Ingileif Jonsdottir, Thorhildur Juliusdottir, Noor Kalsheker, Abdumadjit Kasimov, John P. Kemp, Katja Kivinen, Kari Klungsøyr, Wai K. Lee, Mads Melbye, Zosia Miedzybrodska, Ashley Moffett, Dilbar Najmutdinova, Firuza Nishanova, Thorunn Olafsdottir, Markus Perola, Fiona Broughton Pipkin, Lucilla Poston, Gordon Prescott, Saedis Saevarsdottir, Damilya Salimbayeva, Paula Juliet Scaife, Line Skotte, Eleonora Staines-Urias, Olafur A. Stefansson, Karina Meden Sørensen, Liv Cecilie Vestrheim Thomsen, Vinicius Tragante, Lill Trogstad, Nigel A. B. Simpson, FINNPEC Consortium, GOPEC Consortium, Tamara Aripova, Juan P. Casas, Anna F. Dominiczak, James J. Walker, Unnur Thorsteinsdottir, Ann-Charlotte Iversen, Bjarke Feenstra, Deborah A. Lawlor, Heather Allison Boyd, Per Magnus, Hannele Laivuori, Nodira Zakhidova, Gulnara Svyatova, Kari Stefansson, Linda Morgan
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Studies to identify maternal variants associated with preeclampsia have been limited by sample size. Here, the authors meta-analyze eight GWAS of 9,515 preeclamptic women, identifying five variants associated with preeclampsia and showing that geneti
Externí odkaz:
https://doaj.org/article/54b589a97a1246bc8db4f581846322e3
Autor:
Jessica van Setten, Jennifer A. Brody, Yalda Jamshidi, Brenton R. Swenson, Anne M. Butler, Harry Campbell, Fabiola M. Del Greco, Daniel S. Evans, Quince Gibson, Daniel F. Gudbjartsson, Kathleen F. Kerr, Bouwe P. Krijthe, Leo-Pekka Lyytikäinen, Christian Müller, Martina Müller-Nurasyid, Ilja M. Nolte, Sandosh Padmanabhan, Marylyn D. Ritchie, Antonietta Robino, Albert V. Smith, Maristella Steri, Toshiko Tanaka, Alexander Teumer, Stella Trompet, Sheila Ulivi, Niek Verweij, Xiaoyan Yin, David O. Arnar, Folkert W. Asselbergs, Joel S. Bader, John Barnard, Josh Bis, Stefan Blankenberg, Eric Boerwinkle, Yuki Bradford, Brendan M. Buckley, Mina K. Chung, Dana Crawford, Marcel den Hoed, Josh C. Denny, Anna F. Dominiczak, Georg B. Ehret, Mark Eijgelsheim, Patrick T. Ellinor, Stephan B. Felix, Oscar H. Franco, Lude Franke, Tamara B. Harris, Hilma Holm, Gandin Ilaria, Annamaria Iorio, Mika Kähönen, Ivana Kolcic, Jan A. Kors, Edward G. Lakatta, Lenore J. Launer, Honghuang Lin, Henry J. Lin, Ruth J. F. Loos, Steven A. Lubitz, Peter W. Macfarlane, Jared W. Magnani, Irene Mateo Leach, Thomas Meitinger, Braxton D. Mitchell, Thomas Munzel, George J. Papanicolaou, Annette Peters, Arne Pfeufer, Peter P. Pramstaller, Olli T. Raitakari, Jerome I. Rotter, Igor Rudan, Nilesh J. Samani, David Schlessinger, Claudia T. Silva Aldana, Moritz F. Sinner, Jonathan D. Smith, Harold Snieder, Elsayed Z. Soliman, Timothy D. Spector, David J. Stott, Konstantin Strauch, Kirill V. Tarasov, Unnur Thorsteinsdottir, Andre G. Uitterlinden, David R. Van Wagoner, Uwe Völker, Henry Völzke, Melanie Waldenberger, Harm Jan Westra, Philipp S. Wild, Tanja Zeller, Alvaro Alonso, Christy L. Avery, Stefania Bandinelli, Emelia J. Benjamin, Francesco Cucca, Marcus Dörr, Luigi Ferrucci, Paolo Gasparini, Vilmundur Gudnason, Caroline Hayward, Susan R. Heckbert, Andrew A. Hicks, J. Wouter Jukema, Stefan Kääb, Terho Lehtimäki, Yongmei Liu, Patricia B. Munroe, Afshin Parsa, Ozren Polasek, Bruce M. Psaty, Dan M. Roden, Renate B. Schnabel, Gianfranco Sinagra, Kari Stefansson, Bruno H. Stricker, Pim van der Harst, Cornelia M. van Duijn, James F. Wilson, Sina A. Gharib, Paul I. W. de Bakker, Aaron Isaacs, Dan E. Arking, Nona Sotoodehnia
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Abnormal PR interval duration is associated with risk for atrial fibrillation and heart block. Here, van Setten et al. identify 44 PR interval loci in a genome-wide association study of over 92,000 individuals and find genetic overlap with QRS durati
Externí odkaz:
https://doaj.org/article/df5945ec05b64c95b22859c1f2918530
Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6
Autor:
Bram P. Prins, Timothy J. Mead, Jennifer A. Brody, Gardar Sveinbjornsson, Ioanna Ntalla, Nathan A. Bihlmeyer, Marten van den Berg, Jette Bork-Jensen, Stefania Cappellani, Stefan Van Duijvenboden, Nikolai T. Klena, George C. Gabriel, Xiaoqin Liu, Cagri Gulec, Niels Grarup, Jeffrey Haessler, Leanne M. Hall, Annamaria Iorio, Aaron Isaacs, Ruifang Li-Gao, Honghuang Lin, Ching-Ti Liu, Leo-Pekka Lyytikäinen, Jonathan Marten, Hao Mei, Martina Müller-Nurasyid, Michele Orini, Sandosh Padmanabhan, Farid Radmanesh, Julia Ramirez, Antonietta Robino, Molly Schwartz, Jessica van Setten, Albert V. Smith, Niek Verweij, Helen R. Warren, Stefan Weiss, Alvaro Alonso, David O. Arnar, Michiel L. Bots, Rudolf A. de Boer, Anna F. Dominiczak, Mark Eijgelsheim, Patrick T. Ellinor, Xiuqing Guo, Stephan B. Felix, Tamara B. Harris, Caroline Hayward, Susan R. Heckbert, Paul L. Huang, J. W. Jukema, Mika Kähönen, Jan A. Kors, Pier D. Lambiase, Lenore J. Launer, Man Li, Allan Linneberg, Christopher P. Nelson, Oluf Pedersen, Marco Perez, Annette Peters, Ozren Polasek, Bruce M. Psaty, Olli T. Raitakari, Kenneth M. Rice, Jerome I. Rotter, Moritz F. Sinner, Elsayed Z. Soliman, Tim D. Spector, Konstantin Strauch, Unnur Thorsteinsdottir, Andrew Tinker, Stella Trompet, André Uitterlinden, Ilonca Vaartjes, Peter van der Meer, Uwe Völker, Henry Völzke, Melanie Waldenberger, James G. Wilson, Zhijun Xie, Folkert W. Asselbergs, Marcus Dörr, Cornelia M. van Duijn, Paolo Gasparini, Daniel F. Gudbjartsson, Vilmundur Gudnason, Torben Hansen, Stefan Kääb, Jørgen K. Kanters, Charles Kooperberg, Terho Lehtimäki, Henry J. Lin, Steven A. Lubitz, Dennis O. Mook-Kanamori, Francesco J. Conti, Christopher H. Newton-Cheh, Jonathan Rosand, Igor Rudan, Nilesh J. Samani, Gianfranco Sinagra, Blair H. Smith, Hilma Holm, Bruno H. Stricker, Sheila Ulivi, Nona Sotoodehnia, Suneel S. Apte, Pim van der Harst, Kari Stefansson, Patricia B. Munroe, Dan E. Arking, Cecilia W. Lo, Yalda Jamshidi
Publikováno v:
Genome Biology, Vol 19, Iss 1, Pp 1-17 (2018)
Abstract Background Genome-wide association studies conducted on QRS duration, an electrocardiographic measurement associated with heart failure and sudden cardiac death, have led to novel biological insights into cardiac function. However, the varia
Externí odkaz:
https://doaj.org/article/90c79bdbde864108a63e5a86f193c9b6
Autor:
Catriona E. Brown, Helen Casey, Anna F. Dominiczak, Shona Kerr, Archie Campbell, Christian Delles
Publikováno v:
Brown, C E, Casey, H, Dominiczak, A F, Kerr, S, Campbell, A & Delles, C 2023, ' Impact of preeclampsia on cardiovascular events: an analysis of the Generation Scotland: Scottish Family Health Study ', Journal of Human Hypertension . https://doi.org/10.1038/s41371-023-00812-2
Preeclampsia is a recognised cause of an increased risk of major adverse cardiovascular events when compared to the background risk in women who did not have hypertensive disorders during pregnancy. The Generation Scotland: Scottish Family Health Stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6cc1d9c782904a2eacb07e24c32369c
https://www.pure.ed.ac.uk/ws/files/337445965/s41371_023_00812_2.pdf
https://www.pure.ed.ac.uk/ws/files/337445965/s41371_023_00812_2.pdf
Autor:
Sheon Mary, Philipp Boder, Sandosh Padmanabhan, Martin W. McBride, Delyth Graham, Christian Delles, Anna F. Dominiczak
Publikováno v:
Hypertension (Dallas, Tex. : 1979). 79(11)
The exclusive expression of uromodulin in the kidneys has made it an intriguing protein in kidney and cardiovascular research. Genome-wide association studies discovered variants of uromodulin that are associated with chronic kidney diseases and hype
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d85d3b208488c7960dc6e505c6f7053e
https://pubmed.ncbi.nlm.nih.gov/36378920
https://pubmed.ncbi.nlm.nih.gov/36378920
Autor:
Zhen‐Yu Zhang, Susana Ravassa, Esther Nkuipou‐Kenfack, Wen‐Yi Yang, Shona M. Kerr, Thomas Koeck, Archie Campbell, Tatiana Kuznetsova, Harald Mischak, Sandosh Padmanabhan, Anna F. Dominiczak, Christian Delles, Jan A. Staessen
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 6, Iss 8 (2017)
BackgroundDetection of preclinical cardiac dysfunction and prognosis of left ventricular heart failure (HF) would allow targeted intervention, and appears to be the most promising approach in its management. Novel biomarker panels may support this ap
Externí odkaz:
https://doaj.org/article/555d29e2c5b64c8da25b0a1861e27026
Autor:
Sandra J. Taler, Fernando Elijovich, Robert M. Carey, Mohammed Barigou, Ian B. Wilkinson, Daniel Batlle, Anna F. Dominiczak, Rhian M. Touyz, J. David Spence, Spoorthy Kulkarni, Morris J. Brown
Publikováno v:
Department of Medicine Publications
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59a4a57d8fcbe661e7ad8e5192c58cec
https://doi.org/10.1161/hypertensionaha.121.17021
https://doi.org/10.1161/hypertensionaha.121.17021