Zobrazeno 1 - 10
of 696
pro vyhledávání: '"A Erzberger"'
The macroscopic behaviour of active matter arises from nonequilibrium microscopic processes. In soft materials, active stresses typically drive macroscopic shape changes, which in turn alter the geometry constraining the microscopic dynamics, leading
Externí odkaz:
http://arxiv.org/abs/2411.15165
Topological defects determine the collective properties of anisotropic materials. How their configurations are controlled is not well understood however, especially in 3D. In living matter moreover, 2D defects have been linked to biological functions
Externí odkaz:
http://arxiv.org/abs/2403.08710
Living materials adapt their shape to signals from the environment, yet the impact of shape changes on signal processing and associated feedback dynamics remain unclear. We find that droplets with signal-responsive interfacial tensions exhibit shape
Externí odkaz:
http://arxiv.org/abs/2402.08664
Autor:
Belousov, Roman, Savino, Sabrina, Moghe, Prachiti, Hiiragi, Takashi, Rondoni, Lamberto, Erzberger, Anna
Cellular Potts models are broadly applied across developmental biology and cancer research. We overcome limitations of the traditional approach, which reinterprets a modified Metropolis sampling as ad hoc dynamics, by introducing a physical timescale
Externí odkaz:
http://arxiv.org/abs/2306.04443
Autor:
Maia-Gil, Mariana, Gorjão, Maria, Belousov, Roman, Espina, Jaime A., Coelho, João, Gouhier, Juliette, Ramos, Ana P., Barriga, Elias H., Erzberger, Anna, Norden, Caren
Publikováno v:
In Current Biology 2 December 2024 34(23):5429-5443
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract DEAD-box ATPases play crucial roles in guiding rRNA restructuring events during the biogenesis of large (60S) ribosomal subunits, but their precise molecular functions are currently unknown. In this study, we present cryo-EM reconstructions
Externí odkaz:
https://doaj.org/article/22b3bbfe69904832aed58b7e5920cb72
Autor:
Eiji Obayashi, Rafael E. Luna, Takashi Nagata, Pilar Martin-Marcos, Hiroyuki Hiraishi, Chingakham Ranjit Singh, Jan Peter Erzberger, Fan Zhang, Haribabu Arthanari, Jacob Morris, Riccardo Pellarin, Chelsea Moore, Ian Harmon, Evangelos Papadopoulos, Hisashi Yoshida, Mahmoud L. Nasr, Satoru Unzai, Bryttney Thompson, Eric Aube, Samantha Hustak, Florian Stengel, Eddie Dagraca, Asokan Ananbandam, Philip Gao, Takeshi Urano, Alan G. Hinnebusch, Gerhard Wagner, Katsura Asano
Publikováno v:
Cell Reports, Vol 43, Iss 6, Pp 114404- (2024)
Externí odkaz:
https://doaj.org/article/0abf4580bb9d47ceb45f9407f4e57f48
Autor:
Ewa Sitarska, Silvia Dias Almeida, Marianne Sandvold Beckwith, Julian Stopp, Jakub Czuchnowski, Marc Siggel, Rita Roessner, Aline Tschanz, Christer Ejsing, Yannick Schwab, Jan Kosinski, Michael Sixt, Anna Kreshuk, Anna Erzberger, Alba Diz-Muñoz
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract To navigate through diverse tissues, migrating cells must balance persistent self-propelled motion with adaptive behaviors to circumvent obstacles. We identify a curvature-sensing mechanism underlying obstacle evasion in immune-like cells. S
Externí odkaz:
https://doaj.org/article/505ca1c735d5448bb63418ff9ca18075
Akademický článek
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rRNA methylation by Spb1 regulates the GTPase activity of Nog2 during 60S ribosomal subunit assembly
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Regulation of 60S biogenesis remains poorly understood. Using cryo-EM, the authors show that failure of Spb1 to methylate the A-loop nucleotide G2922 prematurely activates the GTPase Nog2, suggesting that Spb1 and Nog2 form a kinetic checkpoint durin
Externí odkaz:
https://doaj.org/article/0079a91e9ebe4720b71e0b1add6eb261