Zobrazeno 1 - 10
of 47
pro vyhledávání: '"A E Namen"'
Autor:
Christine Heufler, Nikolaus Romani, A E Namen, Franz Koch, Gerda Topar, A Grasseger, Ursula Stanzl, Gerold Schuler
Publikováno v:
The Journal of Experimental Medicine
Interleukin 7 (IL-7) was originally identified as a growth factor for B cell progenitors, and subsequently has been shown to exert proliferative effects on T cell progenitors and mature peripheral T cells as well. Constitutive IL-7 mRNA expression so
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83b02ebc21e64fb44fb07d50a1c11dc5
http://europepmc.org/articles/PMC2191157
http://europepmc.org/articles/PMC2191157
Publikováno v:
European Journal of Immunology. 21:2977-2985
The draining lymph nodes of mice injected with viable syngeneic tumor cells contain lymphoid cells capable of generating anti-tumor cytotoxic T lymphocytes (CTL) during a 4-day in vitro culture period and intravenous infusion of relatively low number
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcc8053350249049cb6f2b0a86497b08
https://doi.org/10.1002/eji.1830211212
https://doi.org/10.1002/eji.1830211212
Publikováno v:
The Journal of Immunology. 147:561-568
Normal mice were injected with IL-7 (500 ng, twice daily) for various periods of time up to 6 days and the cellularity and phenotypic composition of the thymus, spleen, lymph node, and bone marrow was assessed. After 6 days of treatment, significant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc4667e191bb39b520e1eed8e6cfdf28
https://doi.org/10.4049/jimmunol.147.2.561
https://doi.org/10.4049/jimmunol.147.2.561
Publikováno v:
The Journal of Immunology. 146:1547-1552
Lymphopenia was induced in mice by a single injection of cyclophosphamide. IL-7 or a control protein were administered to the mice twice daily and the cellularity and composition of the spleen, lymph node, bone marrow, and thymus were determined at v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::223d8425e3877debdffe93a2c31cb15a
https://doi.org/10.4049/jimmunol.146.5.1547
https://doi.org/10.4049/jimmunol.146.5.1547
Autor:
Robert W. Overell, Lauretta Clark, David Lynch, Rita Jerzy, Ann Schmierer, Karen E. Weisser, Anthony E. Namen, Raymond G. Goodwin
Publikováno v:
Molecular and Cellular Biology. 11:1590-1597
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3fde43f07bf804fac2163b78d80303a3
https://doi.org/10.1128/mcb.11.3.1590-1597.1991
https://doi.org/10.1128/mcb.11.3.1590-1597.1991
Autor:
A E Namen, Rita Jerzy, R. W. Overell, D Lynch, K. E. Weisser, A E Schmierer, L Clark, Raymond G. Goodwin
Publikováno v:
Molecular and Cellular Biology. 11:1590-1597
In this study, we have constructed retroviral vectors expressing the interleukin-7 (IL-7) cDNA and have used infection with these retroviruses to express this cytokine endogenously in an IL-7-dependent pre-B-cell line. Infection with IL-7 retroviruse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6846df47716cfebc9776750c404378b3
https://doi.org/10.1128/mcb.11.3.1590
https://doi.org/10.1128/mcb.11.3.1590
Autor:
Anthony E. Namen, Carolynn E. Pietrangeli, Kay L. Medina, Paul W. Kincade, K Miyake, Shin Ichi Hayashi, Katsuhiko Ishihara
Publikováno v:
Developmental Immunology
Five stromal-cell-dependent lymphocyte clones are described that correspond to late pre-B or early B-cell stages of differentiation.They are useful for determining the molecular requirements for pre-B replication, for studying the stromal cells that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1aff730e99f10040463e641c75dcd17
https://doi.org/10.1155/1991/79721
https://doi.org/10.1155/1991/79721
Autor:
A E, Namen, P J, Morrissey
Publikováno v:
Current protocols in immunology.
This unit describes an assay system to detect biologically active interleukin 7 (IL-7). The target or indicator cells are a clonally derived long-term pre-B cell line designated IxN/2bx (or, more simply, 2bx). These cells demonstrate an absolute spec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::34ba06c01a1eb5cede0e6b1ee8dcf302
https://pubmed.ncbi.nlm.nih.gov/18432820
https://pubmed.ncbi.nlm.nih.gov/18432820
Publikováno v:
The Journal of Immunology. 144:3015-3020
The regulation of murine T cell proliferation by IL-7 was investigated. Highly purified resting splenic T cells were induced to proliferate in a short term assay by IL-7 in the presence of the comitogen, Con A. The proliferation of these resting T ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c6c188abd4d803a2cc1eed41fcfc780
https://doi.org/10.4049/jimmunol.144.8.3015
https://doi.org/10.4049/jimmunol.144.8.3015
Autor:
Steven F. Ziegler, Linda S. Park, Steven K. Dower, Della Friend, Steve Gimpel, Rita Jerzy, David Cosman, Raymond G. Goodwin, Ben A. Falk, Anthony E. Namen, Carl J. March
Publikováno v:
Cell. 60:941-951
cDNA clones encoding the human and murine interleukin-7 (IL-7) receptor were isolated and expressed in COS-7 cells. Binding of radiolabeled IL-7 to the recombinant IL-7 receptors produced curvilinear Scatchard plots containing high and low affinity c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7ea67988149d288dd9ccd69e4e177db
https://doi.org/10.1016/0092-8674(90)90342-c
https://doi.org/10.1016/0092-8674(90)90342-c