Zobrazeno 1 - 10
of 273
pro vyhledávání: '"A E Horne"'
Autor:
Katherine L. Fenn, Jim E. Horne, Joel A. Crossley, Nils Böhringer, Romany J. Horne, Till F. Schäberle, Antonio N. Calabrese, Sheena E. Radford, Neil A. Ranson
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract The outer membrane is a formidable barrier that protects Gram-negative bacteria against environmental threats. Its integrity requires the correct folding and insertion of outer membrane proteins (OMPs) by the membrane-embedded β-barrel asse
Externí odkaz:
https://doaj.org/article/e2d6b62a22094d6bb6804c36a81d4e8a
Autor:
J. E. Horne, C. Goldblatt
Publikováno v:
Geochemistry, Geophysics, Geosystems, Vol 25, Iss 4, Pp n/a-n/a (2024)
Abstract We present Earth's Oxygenation and Natural Systematics (EONS): a new, fully coupled biogeochemical model of the atmosphere, ocean, and their interactions with the geosphere, which can reproduce major features of Earth's evolution following t
Externí odkaz:
https://doaj.org/article/adda278ba36240b19ced30f57df8d990
Autor:
Paul White, Samuel F. Haysom, Matthew G. Iadanza, Anna J. Higgins, Jonathan M. Machin, James M. Whitehouse, Jim E. Horne, Bob Schiffrin, Charlotte Carpenter-Platt, Antonio N. Calabrese, Kelly M. Storek, Steven T. Rutherford, David J. Brockwell, Neil A. Ranson, Sheena E. Radford
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
The folding of outer membrane proteins (OMPs) is catalyzed by the βbarrel assembly machinery (BAM). Here, structural and functional analyses of BAM stabilized in distinct conformations elucidate the roles of lateral gate opening and interactions of
Externí odkaz:
https://doaj.org/article/bf4f9d65548640299d6a3b164c8b8b9d
Autor:
Matthew G. Iadanza, Bob Schiffrin, Paul White, Matthew A. Watson, Jim E. Horne, Anna J. Higgins, Antonio N. Calabrese, David J. Brockwell, Roman Tuma, Antreas C. Kalli, Sheena E. Radford, Neil A. Ranson
Publikováno v:
Communications Biology, Vol 3, Iss 1, Pp 1-14 (2020)
With cryo-EM, single-molecule FRET and MD simulations, Iadanza et al. characterise the membrane protein insertase complex BAM in lipid bilayer nanodiscs. They show that the β-barrel domain of BamA is in a ‘lateral open’ conformation, and that BA
Externí odkaz:
https://doaj.org/article/cc183779d41f4d5aabd191eaa4c934aa
Autor:
Antonio N. Calabrese, Bob Schiffrin, Matthew Watson, Theodoros K. Karamanos, Martin Walko, Julia R. Humes, Jim E. Horne, Paul White, Andrew J. Wilson, Antreas C. Kalli, Roman Tuma, Alison E. Ashcroft, David J. Brockwell, Sheena E. Radford
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
The chaperone SurA is involved in outer membrane protein (OMP) biogenesis in Gram-negative bacteria, but its mechanism of action is not fully understood. Combining mass spectrometric, biophysical and computational approaches, the authors here show ho
Externí odkaz:
https://doaj.org/article/2047c9564bc341c98f0fa558c55a100a
Autor:
Samuel F. Haysom, Jonathan Machin, James M. Whitehouse, Jim E. Horne, Katherine Fenn, Yue Ma, Hassane El Mkami, Nils Böhringer, Till F. Schäberle, Neil A. Ranson, Sheena E. Radford, Christos Pliotas
Publikováno v:
Angewandte Chemie International Edition.
C.P. acknowledges the Biotechnology and Biological Sciences Research Council (BBSRC) (BB/S018069/1; BB/W019795/1) for funding. cwEPR data were collected at the Pliotas Laboratory (BB/S018069/1) and PELDOR data were collected at the University of St A
Autor:
Alfonso Hoyos-Martinez, Michael E. Scheurer, Wendy Allen-Rhoades, M. Fatih Okcu, Vincent E. Horne
Publikováno v:
Journal of Adolescent and Young Adult Oncology.
Publikováno v:
The Journal of Men’s Studies. 30:271-290
Men comprise a small minority of the nursing workforce and there has been little increase in the numbers of men in nursing during the last three decades. This study investigated lived experiences of male nurses to understand reasons men remain a smal
Autor:
RAYMOND H. BATE, DAVID J. HORNE, SARAH E. HORNE, LYNDSEY DOUGLAS, C. GILES MILLER, ALAN R. LORD
Publikováno v:
Zootaxa. 5098:1-84
Type material of 10 genera, one subgenus, 110 species and 28 subspecies described by Wicher (1959), Krömmelbein (1961, 1962, 1963, 1964a,b, 1965a,b), Krömmelbein & Weber (1971) and Bate (1972, 1994) are re-illustrated using optical digital technolo
Autor:
A. Popkova, K. Adams, S. Boublil, R. K. Choudhary, E. Horne, L. Ju, T. Kaur, D. McGoran, D. Wood, M. Zadnik, D. G. Blair, D. F. Treagust
Publikováno v:
The Sixteenth Marcel Grossmann Meeting.