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Akademický článek

Impacts of forced and internal climate variability on changes in convective environments over the eastern United States

Autor: Megan E. Franke, James W. Hurrell, Kristen L. Rasmussen, Lantao Sun

Publikováno v: Frontiers in Climate, Vol 6 (2024)

Hazards from convective weather pose a serious threat to the contiguous United States (CONUS) every year. Previous studies have examined how future projected changes in climate might impact the frequency and intensity of convective weather using simu

Externí odkaz: https://doaj.org/article/94e31d6a1b1c4f5ca2d2f2b56e6d4448

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Akademický článek

Gemcitabine therapeutically disrupts essential SIRT1-mediated p53 repression in atypical teratoid/rhabdoid tumors

Autor: Dennis S. Metselaar, Michaël H. Meel, Joshua R. Goulding, Aimeé du Chatinier, Leyla Rigamonti, Piotr Waranecki, Neal Geisemeyer, Mark C. de Gooijer, Marjolein Breur, Jan Koster, Sophie E.M. Veldhuijzen van Zanten, Marianna Bugiani, Niels E. Franke, Alyssa Reddy, Pieter Wesseling, Gertjan J.L. Kaspers, Esther Hulleman

Publikováno v: Cell Reports Medicine, Vol 5, Iss 9, Pp 101700- (2024)

Summary: Atypical teratoid/rhabdoid tumors (ATRTs) are highly malignant embryonal tumors of the central nervous system with a dismal prognosis. Using a newly developed and validated patient-derived ATRT culture and xenograft model, alongside a panel

Externí odkaz: https://doaj.org/article/dad8aa161f6e4aad834b1c8a6839ea6b

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Atypical teratoid/rhabdoid tumoroids reveal subgroup-specific drug vulnerabilities

Autor: Irene Paassen, Justin Williams, Carla Ríos Arceo, Femke Ringnalda, Kimberly Shea Mercer, Juliane L. Buhl, Natalia Moreno, Aniello Federico, Niels E. Franke, Mariette Kranendonk, Santhosh A. Upadhyaya, Kornelius Kerl, Marc van de Wetering, Hans Clevers, Marcel Kool, Eelco W. Hoving, Martine F. Roussel, Jarno Drost

Publikováno v: Oncogene. 42:1661-1671

Atypical teratoid/rhabdoid tumors (ATRTs) represent a rare, but aggressive pediatric brain tumor entity. They are genetically defined by alterations in the SWI/SNF chromatin remodeling complex members SMARCB1 or SMARCA4. ATRTs can be further classifi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::93aa090d880b312bb13f70514ff04ba7
https://doi.org/10.1038/s41388-023-02681-y

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Akademický článek

Abstract QS6: Multi-institutional Testing Of A 3D Printed Cleft Lip Model For Plastic Surgical Training

Autor: Edward Nahabet, MD, Anthony A. Bertrand, MD, MBA, Raquel Ulma, MD, DDS, Miles J. Pfaff, MD, Julia R. Ayeroff, BA, Hannah Riedle, MS, Hi’ilani M.K. Potemra, BS, Johnny Lin, PhD, Jorg E. franke, PhD, Russell R. Reid, MD, PhD, Justine C. Lee, MD, PhD

Publikováno v: Plastic and Reconstructive Surgery, Global Open, Vol 8, Iss 4S, Pp 140-140 (2020)

Externí odkaz: https://doaj.org/article/7daeaf1370624a4789cb55dfee28883e

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Intermolecular Haloamination: Double Functionalization for Accesses to Vicinal Haloamines Involving Alkenes and Alkynes

Publikováno v: Mini-Reviews in Organic Chemistry. 18:339-360

Haloamination (or called aminohalogenation) upon the C-C unsaturated bonds is an important amino functionalization, which can introduce the halogen atoms accompanying with the amino groups into the substrate backbones in a tandem manner. Over the pas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e0a0542eb8b4f5ad4580ac1217ba5376
https://doi.org/10.2174/1570193x17999200719134419

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Akademický článek

Infant formula containing galacto-and fructo-oligosaccharides and Bifidobacterium breve M-16V supports adequate growth and tolerance in healthy infants in a randomised, controlled, double-blind, prospective, multicentre study

Autor: M. Abrahamse-Berkeveld, M. Alles, E. Franke-Beckmann, K. Helm, R. Knecht, R. Köllges, B. Sandner, J. Knol, K. Ben Amor, A. Bufe

Publikováno v: Journal of Nutritional Science, Vol 5 (2016)

The objective of the present study was to evaluate the growth and tolerance in healthy, term infants consuming a synbiotic formula with daily weight gain as the primary outcome. In a randomised, controlled, double-blind, multicentre, intervention stu

Externí odkaz: https://doaj.org/article/17bc043aa7334c7bb1a06e374e7b3fed

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Transient Hepatotoxicity Induced by Vinblastine in a Young Girl with Chiasmatic Low Grade Glioma

Autor: Geert Jan Blok, Antoinette Y.N. Schouten-van Meeteren, Marsha L. Voll, Niels E. Franke

Publikováno v: Current Drug Safety. 15:231-235

Background: Vinblastine (VBL) is a cytostatic drug frequently applied in children with lymphoma and progressive low-grade glioma (LGG), with hematotoxicity as the main side effect. Case Report: Here, the case of a 7-month-old girl with tumor progress

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c6bbdcf5f49bdb848038330e92a84a07
https://doi.org/10.2174/1574886315666200719013523

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Evaluation of the role of respiratory syncytial virus surface glycoproteins F and G on viral stability and replication: implications for future vaccine design

Autor: Megan E. Franke, Emily F. Hasik, Christopher C. Stobart, Caitlin E. Haas, Karina N. Latsko, Benjamin C. Nick, Alyssa M. Abdelnour, Sean T. Berthrong, Jenna M. Nosek, Christina A. Rostad, Katelyn R. Castiglia, Nathan A. Junod, Darby M. DeFord, Martin L. Moore

Publikováno v: Journal of General Virology. 100:1112-1122

Respiratory syncytial virus (RSV) remains a leading cause of infant mortality worldwide and exhaustive international efforts are underway to develop a vaccine. However, vaccine development has been hindered by a legacy of vaccine-enhanced disease, po

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0fa1b7a936a8a55d20de50d82a9387a
https://doi.org/10.1099/jgv.0.001287

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Akademický článek

Higher ratio immune versus constitutive proteasome level as novel indicator of sensitivity of pediatric acute leukemia cells to proteasome inhibitors

Autor: Denise Niewerth, Niels E. Franke, Gerrit Jansen, Yehuda G. Assaraf, Johan van Meerloo, Christopher J. Kirk, Jeremiah Degenhardt, Janet Anderl, Aaron D. Schimmer, Sonja Zweegman, Valerie de Haas, Terzah M. Horton, Gertjan J.L. Kaspers, Jacqueline Cloos

Publikováno v: Haematologica, Vol 98, Iss 12 (2013)

The ex vivo sensitivity of pediatric leukemia cells to the proteasome inhibitor bortezomib was compared to 3 next generation proteasome inhibitors: the epoxyketone-based irreversible proteasome inhibitors carfilzomib, its orally bio-available analog

Externí odkaz: https://doaj.org/article/c2e0671e06624cadbb28d8bbbeaabb4e

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Gaia Early Data Release 3: Acceleration of the Solar System from Gaia astrometry

Autor: Klioner, S.A. Mignard, F. Lindegren, L. Bastian, U. McMillan, P.J. Hernández, J. Hobbs, D. Ramos-Lerate, M. Biermann, M. Bombrun, A. De Torres, A. Gerlach, E. Geyer, R. Hilger, T. Lammers, U. Steidelmüller, H. Stephenson, C.A. Brown, A.G.A. Vallenari, A. Prusti, T. De Bruijne, J.H.J. Babusiaux, C. Creevey, O.L. Evans, D.W. Eyer, L. Hutton, A. Jansen, F. Jordi, C. Luri, X. Panem, C. Pourbaix, D. Randich, S. Sartoretti, P. Soubiran, C. Walton, N.A. Arenou, F. Bailer-Jones, C.A.L. Cropper, M. Drimmel, R. Katz, D. Lattanzi, M.G. Van Leeuwen, F. Bakker, J. Castañeda, J. De Angeli, F. Ducourant, C. Fabricius, C. Fouesneau, M. Frémat, Y. Guerra, R. Guerrier, A. Guiraud, J. Jean-Antoine Piccolo, A. Masana, E. Messineo, R. Mowlavi, N. Nicolas, C. Nienartowicz, K. Pailler, F. Panuzzo, P. Riclet, F. Roux, W. Seabroke, G.M. Sordo, R. Tanga, P. Thévenin, F. Gracia-Abril, G. Portell, J. Teyssier, D. Altmann, M. Andrae, R. Bellas-Velidis, I. Benson, K. Berthier, J. Blomme, R. Brugaletta, E. Burgess, P.W. Busso, G. Carry, B. Cellino, A. Cheek, N. Clementini, G. Damerdji, Y. Davidson, M. Delchambre, L. Dell'Oro, A. Fernández-Hernández, J. Galluccio, L. García-Lario, P. Garcia-Reinaldos, M. González-Núñez, J. Gosset, E. Haigron, R. Halbwachs, J.-L. Hambly, N.C. Harrison, D.L. Hatzidimitriou, D. Heiter, U. Hestroffer, D. Hodgkin, S.T. Holl, B. Janßen, K. Jevardat De Fombelle, G. Jordan, S. Krone-Martins, A. Lanzafame, A.C. Löffler, W. Lorca, A. Manteiga, M. Marchal, O. Marrese, P.M. Moitinho, A. Mora, A. Muinonen, K. Osborne, P. Pancino, E. Pauwels, T. Recio-Blanco, A. Richards, P.J. Riello, M. Rimoldini, L. Robin, A.C. Roegiers, T. Rybizki, J. Sarro, L.M. Siopis, C. Smith, M. Sozzetti, A. Ulla, A. Utrilla, E. Van Leeuwen, M. Van Reeven, W. Abbas, U. Abreu Aramburu, A. Accart, S. Aerts, C. Aguado, J.J. Ajaj, M. Altavilla, G. Álvarez, M.A. Álvarez Cid-Fuentes, J. Alves, J. Anderson, R.I. Anglada Varela, E. Antoja, T. Audard, M. Baines, D. Baker, S.G. Balaguer-Núñez, L. Balbinot, E. Balog, Z. Barache, C. Barbato, D. Barros, M. Barstow, M.A. Bartolomé, S. Bassilana, J.-L. Bauchet, N. Baudesson-Stella, A. Becciani, U. Bellazzini, M. Bernet, M. Bertone, S. Bianchi, L. Blanco-Cuaresma, S. Boch, T. Bossini, D. Bouquillon, S. Bramante, L. Breedt, E. Bressan, A. Brouillet, N. Bucciarelli, B. Burlacu, A. Busonero, D. Butkevich, A.G. Buzzi, R. Caffau, E. Cancelliere, R. Cánovas, H. Cantat-Gaudin, T. Carballo, R. Carlucci, T. Carnerero, M.I. Carrasco, J.M. Casamiquela, L. Castellani, M. Castro-Ginard, A. Castro Sampol, P. Chaoul, L. Charlot, P. Chemin, L. Chiavassa, A. Comoretto, G. Cooper, W.J. Cornez, T. Cowell, S. Crifo, F. Crosta, M. Crowley, C. Dafonte, C. Dapergolas, A. David, M. David, P. De Laverny, P. De Luise, F. De March, R. De Ridder, J. De Souza, R. De Teodoro, P. Del Peloso, E.F. Del Pozo, E. Delgado, A. Delgado, H.E. Delisle, J.-B. Di Matteo, P. Diakite, S. Diener, C. Distefano, E. Dolding, C. Eappachen, D. Enke, H. Esquej, P. Fabre, C. Fabrizio, M. Faigler, S. Fedorets, G. Fernique, P. Fienga, A. Figueras, F. Fouron, C. Fragkoudi, F. Fraile, E. Franke, F. Gai, M. Garabato, D. Garcia-Gutierrez, A. García-Torres, M. Garofalo, A. Gavras, P. Giacobbe, P. Gilmore, G. Girona, S. Giuffrida, G. Gomez, A. Gonzalez-Santamaria, I. González-Vidal, J.J. Granvik, M. Gutiérrez-Sánchez, R. Guy, L.P. Hauser, M. Haywood, M. Helmi, A. Hidalgo, S.L. Hładczuk, N. Holland, G. Huckle, H.E. Jasniewicz, G. Jonker, P.G. Juaristi Campillo, J. Julbe, F. Karbevska, L. Kervella, P. Khanna, S. Kochoska, A. Kordopatis, G. Korn, A.J. Kostrzewa-Rutkowska, Z. Kruszyńska, K. Lambert, S. Lanza, A.F. Lasne, Y. Le Campion, J.-F. Le Fustec, Y. Lebreton, Y. Lebzelter, T. Leccia, S. Leclerc, N. Lecoeur-Taibi, I. Liao, S. Licata, E. Lindstrøm, H.E.P. Lister, T.A. Livanou, E. Lobel, A. Madrero Pardo, P. Managau, S. Mann, R.G. Marchant, J.M. Marconi, M. Marcos Santos, M.M.S. Marinoni, S. Marocco, F. Marshall, D.J. Martin Polo, L. Martín-Fleitas, J.M. Masip, A. Massari, D. Mastrobuono-Battisti, A. Mazeh, T. Messina, S. Michalik, D. Millar, N.R. Mints, A. Molina, D. Molinaro, R. Molnár, L. Montegriffo, P. Mor, R. Morbidelli, R. Morel, T. Morris, D. Mulone, A.F. Munoz, D. Muraveva, T. Murphy, C.P. Musella, I. Noval, L. Ordénovic, C. Orrù, G. Osinde, J. Pagani, C. Pagano, I. Palaversa, L. Palicio, P.A. Panahi, A. Pawlak, M. Peñalosa Esteller, X. Penttilä, A. Piersimoni, A.M. Pineau, F.-X. Plachy, E. Plum, G. Poggio, E. Poretti, E. Poujoulet, E. Prša, A. Pulone, L. Racero, E. Ragaini, S. Rainer, M. Raiteri, C.M. Rambaux, N. Ramos, P. Re Fiorentin, P. Regibo, S. Reylé, C. Ripepi, V. Riva, A. Rixon, G. Robichon, N. Robin, C. Roelens, M. Rohrbasser, L. Romero-Gómez, M. Rowell, N. Royer, F. Rybicki, K.A. Sadowski, G. Sagristà Sellés, A. Sahlmann, J. Salgado, J. Salguero, E. Samaras, N. Sanchez Gimenez, V. Sanna, N. Santoveña, R. Sarasso, M. Schultheis, M. Sciacca, E. Segol, M. Segovia, J.C. Ségransan, D. Semeux, D. Siddiqui, H.I. Siebert, A. Siltala, L. Slezak, E. Smart, R.L. Solano, E. Solitro, F. Souami, D. Souchay, J. Spagna, A. Spoto, F. Steele, I.A. Süveges, M. Szabados, L. Szegedi-Elek, E. Taris, F. Tauran, G. Taylor, M.B. Teixeira, R. Thuillot, W. Tonello, N. Torra, F. Torra, J. Turon, C. Unger, N. Vaillant, M. Van Dillen, E. Vanel, O. Vecchiato, A. Viala, Y. Vicente, D. Voutsinas, S. Weiler, M. Wevers, T. Wyrzykowski, L. Yoldas, A. Yvard, P. Zhao, H. Zorec, J. Zucker, S. Zurbach, C. Zwitter, T.

Context. Gaia Early Data Release 3 (Gaia EDR3) provides accurate astrometry for about 1.6 million compact (QSO-like) extragalactic sources, 1.2 million of which have the best-quality five-parameter astrometric solutions. Aims. The proper motions of Q

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2127::403709634f34b4d406a46c6f7a485941
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3068453

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