Zobrazeno 1 - 10
of 19
pro vyhledávání: '"A E Davis rd"'
Publikováno v:
Journal of Clinical Investigation. 95:1299-1305
We have determined the cause of an unusual C1 inhibitor abnormality in a large kindred. We previously found that half of serum C1 inhibitor molecules in affected kindred members are normal. The other half complexed with C1s but showed little complex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6f6665e9eb59e243e93a25ea997a119
https://doi.org/10.1172/jci117780
https://doi.org/10.1172/jci117780
Publikováno v:
Journal of Biological Chemistry. 269:9669-9674
Treatment of the hepatoma cell line, Hep3B, with gamma-interferon (IFN) enhanced expression of C1 inhibitor (C1INH) mRNA, primarily due to an enhanced transcription rate. Hep3B cells transfected with reporter constructs containing various regions of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ab8c7978a4a282b02e75de459626c95
https://doi.org/10.1016/s0021-9258(17)36934-x
https://doi.org/10.1016/s0021-9258(17)36934-x
Autor:
R.C. Strunk, John J. Bissler, K. S. Aulak, A E Davis rd, Richard B. Parad, Eric Eldering, F S Rosen, C E Hack, H P Stecklein, J Kramer
Publikováno v:
Nature genetics, 1(5), 354-358. Nature Publishing Group
Heterozygosity for a mutant dysfunctional C1 inhibitor protein, a member of the serine proteinase inhibitor (serpin) superfamily, results in type II hereditary angioneurotic oedema. We identified a "hinge" region mutation in C1 inhibitor with a Val t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f6b3c826a80aa47b876a64d8123f38b
https://doi.org/10.1038/ng0892-354
https://doi.org/10.1038/ng0892-354
Publikováno v:
Journal of Biological Chemistry. 261:7526-7530
gpL115, the surface sialoglycoprotein that is defective in lymphocytes of Wiskott-Aldrich syndrome patients has been purified from large scale cultures of the lymphoblastoid line CEM. The purification entails cell lysis and solubilization of gpL115 w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db45fbfe3ee78e6c7a03a011113dafae
https://doi.org/10.1016/s0021-9258(17)38423-5
https://doi.org/10.1016/s0021-9258(17)38423-5
Autor:
P J Hansen, A E Davis rd, H R Colten, L P Einstein, Chester A. Alper, Mark Ballow, J S Davis th, Fred S. Rosen
Publikováno v:
Journal of Clinical Investigation. 60:963-969
Human monocytes synthesized the third component of complement (C3) up to 5 wk in vitro. Evidence for net C3 synthesis was based on (a) incorporation of 14C-labeled amino acids into C3 protein, (b) indentity of the allotype of C3 produced in vitro wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8a7a6ee4d1e88477ec62934f47c0da7
https://doi.org/10.1172/jci108876
https://doi.org/10.1172/jci108876
Publikováno v:
Journal of Clinical Investigation. 80:1640-1643
Hereditary angioneurotic edema (HANE) results from the deficiency of the inhibitor of the first component of human complement (C1-INH). It is inherited as an autosomal dominant trait. Heterogeneity of this defect has been shown at the protein and mRN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9a04d105942af6224a35d5b5fefa608
https://doi.org/10.1172/jci113252
https://doi.org/10.1172/jci113252
Publikováno v:
The Journal of clinical investigation. 79(3)
Hereditary angioneurotic edema (HANE) results from deficiency of complement 1 inhibitor (C1 INH). In type I HANE, C1 INH is present in serum at levels 5-30% of normals. Using cultured monocytes and biosynthetic labeling of proteins, C1 INH was detect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4e15eb94ed3b2c847d446ff67016727
https://pubmed.ncbi.nlm.nih.gov/3818946
https://pubmed.ncbi.nlm.nih.gov/3818946
Autor:
Dianne M. Kenney, A E Davis rd
Factor D, when preincubated with platelet suspensions, at concentrations as low as 1.2 micrograms/ml, inhibited thrombin-induced platelet aggregation. No inhibition of collagen or arachidonic acid-induced platelet aggregation was found. Inhibition oc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50c305719e5188ee6b2e8f86714012a5
https://europepmc.org/articles/PMC372173/
https://europepmc.org/articles/PMC372173/
Publikováno v:
Scopus-Elsevier
The role of particle-bound complement proteins in the induction of noncytotoxic enzyme release from human granulocytes was investigated with the use of sera genetically deficient in complement and highly purified complement components. Release of his
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f1577f45346f091203a3b3ac500546a
https://europepmc.org/articles/PMC372068/
https://europepmc.org/articles/PMC372068/
Publikováno v:
Annual Review of Physical Chemistry; 2024, Vol. 75 Issue 1, p257-281, 20p