Zobrazeno 1 - 10
of 421
pro vyhledávání: '"A E Cass"'
Autor:
Mahalakshmi Kumaran, Preethi Krishnan, Carol E. Cass, Roland Hubaux, Wan Lam, Yutaka Yasui, Sambasivarao Damaraju
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Abstract Copy Number Variants (CNVs) are a class of structural variations of DNA. Germline CNVs are known to confer disease susceptibility, but their role in breast cancer warrants further investigations. We hypothesized that breast cancer associated
Externí odkaz:
https://doaj.org/article/0a8aab14164b4afaaa9d425c68417891
Autor:
Robert J. Reklow, Tucaaue S. Alvares, Yong Zhang, Ana P. Miranda Tapia, Vivian Biancardi, Alexis K. Katzell, Sara M. Frangos, Megan A. Hansen, Alexander W. Toohey, Carol E. Cass, James D. Young, Silvia Pagliardini, Detlev Boison, Gregory D. Funk
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
Exploration of purinergic signaling in brainstem homeostatic control processes is challenging the traditional view that the biphasic hypoxic ventilatory response, which comprises a rapid initial increase in breathing followed by a slower secondary de
Externí odkaz:
https://doaj.org/article/e433dca14c03434abf16ad50ac268923
Autor:
Philippe Gros, Carol E. Cass, Morris J. Robins, Yunshan Peng, Delores Mowles, Normand Groulx, Vijaya L. Damaraju, Jie Cai
Supplementary Figure 1 from Two Distinct Molecular Mechanisms Underlying Cytarabine Resistance in Human Leukemic Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35420a2c1a15ea102e9d64786a81328a
https://doi.org/10.1158/0008-5472.22375320
https://doi.org/10.1158/0008-5472.22375320
Data from Two Distinct Molecular Mechanisms Underlying Cytarabine Resistance in Human Leukemic Cells
Autor:
Philippe Gros, Carol E. Cass, Morris J. Robins, Yunshan Peng, Delores Mowles, Normand Groulx, Vijaya L. Damaraju, Jie Cai
To understand the mechanism of cellular resistance to the nucleoside analogue cytarabine (1-β-d-arabinofuranosylcytosine, AraC), two resistant derivatives of the human leukemic line CCRF-CEM were obtained by stepwise selection in different concentra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2c75ff89816a4cf3a98cee8ce68c5c6
https://doi.org/10.1158/0008-5472.c.6497769
https://doi.org/10.1158/0008-5472.c.6497769
Autor:
Philippe Gros, Carol E. Cass, Morris J. Robins, Yunshan Peng, Delores Mowles, Normand Groulx, Vijaya L. Damaraju, Jie Cai
Supplementary Table 1 from Two Distinct Molecular Mechanisms Underlying Cytarabine Resistance in Human Leukemic Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19c237039b567faa26bf2b2ad873fbc7
https://doi.org/10.1158/0008-5472.22375317
https://doi.org/10.1158/0008-5472.22375317
Autor:
Florian C. Maier, Anna Schweifer, Vijaya L. Damaraju, Carol E. Cass, Gregory D. Bowden, Walter Ehrlichmann, Manfred Kneilling, Bernd J. Pichler, Friedrich Hammerschmidt, Gerald Reischl
Publikováno v:
Pharmaceuticals, Vol 12, Iss 1, p 31 (2019)
The benefits of PET imaging of tumor hypoxia in patient management has been demonstrated in many examples and with various tracers over the last years. Although, the optimal hypoxia imaging agent has yet to be found, 2-nitroimidazole (azomycin) sugar
Externí odkaz:
https://doaj.org/article/6eea80e75643418a81865cbc411b6abd
Autor:
Marc St George, Ahmed T Ayoub, Asok Banerjee, Cassandra D M Churchill, Philip Winter, Mariusz Klobukowski, Carol E Cass, Richard F Ludueña, Jack A Tuszynski, Sambasivarao Damaraju
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0129168 (2015)
Our previous work identified an intermediate binding site for taxanes in the microtubule nanopore. The goal of this study was to test derivatives of paclitaxel designed to bind to this intermediate site differentially depending on the isotype of β-t
Externí odkaz:
https://doaj.org/article/f52f0efb56234a809812dbd19309eb40
Autor:
Carol E. Cass, Sunita Ghosh, Sambasivarao Damaraju, Mahalakshmi Kumaran, John R. Mackey, Wei Zheng, Yutaka Yasui, Anil Abraham Joy
Publikováno v:
International Journal of Cancer
We previously identified a novel breast cancer susceptibility variant on chromosome 4q31.22 locus (rs1429142) conferring risk among women of European ancestry. Here, we report replication of findings, validation of the variant in diverse populations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68191f5cf3ef57301370e55023216351
https://doi.org/10.1002/ijc.32407
https://doi.org/10.1002/ijc.32407
Autor:
Yadav Sapkota, John R Mackey, Raymond Lai, Conrado Franco-Villalobos, Sasha Lupichuk, Paula J Robson, Karen Kopciuk, Carol E Cass, Yutaka Yasui, Sambasivarao Damaraju
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e64896 (2014)
Genome-wide association studies (GWASs) have identified low-penetrance common variants (i.e., single nucleotide polymorphisms, SNPs) associated with breast cancer susceptibility. Although GWASs are primarily focused on single-locus effects, gene-gene
Externí odkaz:
https://doaj.org/article/18b00cec1b8042a7b7c124edac267661
Autor:
Yadav Sapkota, Sunita Ghosh, Raymond Lai, Bradley P Coe, Carol E Cass, Yutaka Yasui, John R Mackey, Sambasivarao Damaraju
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e53850 (2013)
Breast cancer recurrence (BCR) is a common treatment outcome despite curative-intent primary treatment of non-metastatic breast cancer. Currently used prognostic and predictive factors utilize tumor-based markers, and are not optimal determinants of
Externí odkaz:
https://doaj.org/article/2285fe0cfbbf425995582c081c331530