Zobrazeno 1 - 10
of 20
pro vyhledávání: '"A E, Watmore"'
Autor:
Ayalew Tefferi, Gordon W. Dewald, Fiona M. Ross, Nicholas C.P. Cross, Ann E. Watmore, D. Dingli, John T. Reilly, Francis H. Grand, Victor Mahaffey, Jack L. Spurbeck
Publikováno v:
British Journal of Haematology. 130:229-232
Chromosome anomalies are detected in approximately half of patients with myelofibrosis with myeloid metaplasia (MMM) although none of the most prevalent lesions are specific to the disease. In a prospective cytogenetic study of 81 patients with MMM,
The t(8;9)(p22;p24) Is a Recurrent Abnormality in Chronic and Acute Leukemia that Fuses PCM1 to JAK2
Autor:
Nick Telford, Rüdiger Hehlmann, Andreas Reiter, Brigitte Schlegelberger, Ute Berger, Danny Vanstraelen, Cornelia Rudolph, Hans-Jochem Kolb, Ilona Blau, Shilani Aruliah, John A Yin, Christoph Walz, Peter C Taylor, Helen F Barker, Claudia Schoch, Aisling O'Driscoll, Ann E. Watmore, Andreas Hochhaus, Nicholas C.P. Cross, Andrew Chase, Fabio Benedetti
Publikováno v:
Cancer Research. 65:2662-2667
We have identified a t(8;9)(p21-23;p23-24) in seven male patients (mean age 50, range 32-74) with diverse hematologic malignancies and clinical outcomes: atypical chronic myeloid leukemia/chronic eosinophilic leukemia (n = 5), secondary acute myeloid
Publikováno v:
British Journal of Haematology. 113:365-368
To identify a commonly deleted region of 13q14 in idiopathic myelofibrosis (IMF), we used fluorescence in situ hybridization analysis to test for deletion of the RB1 and BRCA2 genes, and the microsatellite loci D13S319 and D13S25, in a series of 25 p
Autor:
G. Wilson, David W. Rowe, J. Bryon, Nick Bown, Simon Cotterill, Michael J. Griffiths, Ann E. Watmore, Elisabeth Vandenberghe, Fiona M. Ross, John T. Reilly, D. J. McMullan, S. J. Vickers, David J. Bunyan
Publikováno v:
British Journal of Haematology. 111:1051-1056
Autor:
D. J. McMullan, David J. Bunyan, Elisabeth Vandenberghe, G. Wilson, Fiona M. Ross, Michael J. Griffiths, S. J. Vickers, Simon Cotterill, John T. Reilly, Nick Bown, J. Bryon, Ann E. Watmore, David W. Rowe
Publikováno v:
British Journal of Haematology. 111:1051-1056
The rearrangements t(8;21)(q22;22) and inv(16)(p13q22) are two of the most frequently seen in acute myeloid leukaemia (AML), accounting for 8% and 4% of cases respectively. Detection of these abnormalities is important for disease management as both
Publikováno v:
Cancer Genetics and Cytogenetics. 105:20-23
Trisomy 15 as a single autosomal abnormality is a rare finding in hematological disorders and has not as yet been associated with any specific disease type. We report 20 cases of trisomy 15 observed in the bone marrow of patients referred for a suspe
Publikováno v:
Cancer Genetics and Cytogenetics. 113:70-72
We have recently cloned the inv(8)(p11q13) in a patient with acute myeloid leukemia (AML), and demonstrated a fusion between the MOZ and TIF2 genes at 8p11 and 8q13, respectively. We have partially characterized a further case of AML with the same ka
Autor:
Ann E. Watmore, Kim Orchard, David Swirsky, Stephanie Coulthard, John M. Goldman, Andrew Chase, Ajay Vora
Publikováno v:
British Journal of Haematology. 100:561-563
We describe two patients with acute myeloid leukaemia (AML) associated with erythrophagocytosis and a pericentric inversion of chromosome 8, inv(8)(p11q13). The haematological features were indistinguishable from those of patients with the t(8;16) sy
Publikováno v:
British journal of haematology. 113(2)
To identify a commonly deleted region of 13q14 in idiopathic myelofibrosis (IMF), we used fluorescence in situ hybridization analysis to test for deletion of the RB1 and BRCA2 genes, and the microsatellite loci D13S319 and D13S25, in a series of 25 p
Publikováno v:
Cancer genetics and cytogenetics. 118(1)
Fluorescence in situ hybridization analysis in an adult with acute monocytic leukemia revealed the complex nature of a rearrangement between chromosomes 10 and 11, which resulted in disruption of the MLL gene. Using a combination of chromosome 10 and