To continue or not to continue? Antipsychotic medication maintenance versus dose-reduction/discontinuation in first episode psychosis: HAMLETT, a pragmatic multicenter single-blind randomized controlled trial

Autor: Marieke J. H. Begemann, Ilse A. Thompson, Wim Veling, Shiral S. Gangadin, Chris N. W. Geraets, Erna van ‘t Hag, Sanne J. Müller-Kuperus, Priscilla P. Oomen, Alban E. Voppel, Mark van der Gaag, Martijn J. Kikkert, Jim Van Os, H. Filip E. Smit, Rikus H. Knegtering, Sybren Wiersma, Luyken H. Stouten, Harm J. Gijsman, Lex Wunderink, Anton B. P. Staring, Selene R. T. Veerman, Amrita G. S. Mahabir, Jörg Kurkamp, Gerdina H. M. Pijnenborg, Natalie D. Veen, Machteld Marcelis, Koen P. Grootens, Gunnar Faber, Nico J. van Beveren, Agaath Been, Truus van den Brink, Maarten Bak, Therese A. M. J. van Amelsvoort, Andrea Ruissen, Christine Blanke, Karin Groen, Lieuwe de Haan, Iris E. C. Sommer

Publikováno v: Trials, Vol 21, Iss 1, Pp 1-19 (2020)

Abstract Background Antipsychotic medication is effective for symptomatic treatment in schizophrenia-spectrum disorders. After symptom remission, continuation of antipsychotic treatment is associated with lower relapse rates and lower symptom severit

Externí odkaz: https://doaj.org/article/9656afbed63342b7995e44fd4b046096

Natural Language Processing Markers for Psychosis and Other Psychiatric Disorders

Autor: Hugo Corona Hernández, Cheryl Corcoran, Amélie M Achim, Janna N de Boer, Tessel Boerma, Sanne G Brederoo, Guillermo A Cecchi, Silvia Ciampelli, Brita Elvevåg, Riccardo Fusaroli, Silvia Giordano, Mathias Hauglid, Arjan van Hessen, Wolfram Hinzen, Philipp Homan, Sybren F de Kloet, Sanne Koops, Gina R Kuperberg, Kritika Maheshwari, Natalia B Mota, Alberto Parola, Roberta Rocca, Iris E C Sommer, Khiet Truong, Alban E Voppel, Marieke van Vugt, Frank Wijnen, Lena Palaniyappan

Publikováno v: Schizophrenia bulletin, 49(2)
Corona Hernández, H, Corcoran, C, Achim, A M, de Boer, J N, Boerma, T, Brederoo, S G, Cecchi, G A, Ciampelli, S, Elvevåg, B, Fusaroli, R, Giordano, S, Hauglid, M, van Hessen, A, Hinzen, W, Homan, P, de Kloet, S F, Koops, S, Kuperberg, G R, Maheshwari, K, Mota, N B, Parola, A, Rocca, R, Sommer, I E C, Truong, K, Voppel, A E, van Vugt, M, Wijnen, F & Palaniyappan, L 2023, ' Natural Language Processing Markers for Psychosis and Other Psychiatric Disorders : Emerging Themes and Research Agenda From a Cross-Linguistic Workshop ', Schizophrenia Bulletin, vol. 49, no. Supplement 2, pp. S86-S92 . https://doi.org/10.1093/schbul/sbac215
Schizophrenia Bulletin, 49(2), S86-S92. Oxford University Press

This workshop summary on natural language processing (NLP) markers for psychosis and other psychiatric disorders presents some of the clinical and research issues that NLP markers might address and some of the activities needed to move in that direct

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::830c90324f86f458f1ba55eeac6b7d5d
https://research.rug.nl/en/publications/cb3d1056-a91a-4648-b764-cda1c48cf182

Speech as a Biomarker for Depression

Autor: Sanne Koops, Sanne G. Brederoo, Janna N. de Boer, Femke G. Nadema, Alban E. Voppel, Iris E. Sommer

Publikováno v: Cns & neurological disorders-Drug targets, 22(2), 152-160

Background: Depression is a debilitating disorder that at present lacks a reliable biomarker to aid in diagnosis and early detection. Recent advances in computational analytic approaches have opened up new avenues in developing such a biomarker by ta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92d841a7a04ff71f5708fe7b4aaacc76
https://doi.org/10.2174/1871527320666211213125847

Characterizing speech heterogeneity in schizophrenia-spectrum disorders

Autor: Priscilla P. Oomen, Janna N. de Boer, Sanne G. Brederoo, Alban E. Voppel, Bodyl A. Brand, Frank N. K. Wijnen, Iris E. C. Sommer

Publikováno v: Journal of psychopathology and clinical science, 131(2), 172-181

Schizophrenia-spectrum disorders (SSD) are highly heterogeneous in risk factors, symptom characteristics, and disease course outcome. Although speech anomalies have long been recognized as a core symptom of SSD, speech markers are an unexplored sourc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99d26165d2db0dbe8324a484723cd836
https://doi.org/10.1037/abn0000736

Anomalies in language as a biomarker for schizophrenia

Autor: Janna de Boer, Iris E. C. Sommer, Sanne Brederoo, A E Voppel

Publikováno v: Current opinion in psychiatry, 33(3), 212-218. LIPPINCOTT WILLIAMS & WILKINS

PURPOSE OF REVIEW: After more than a century of neuroscience research, reproducible, clinically relevant biomarkers for schizophrenia have not yet been established. This article reviews current advances in evaluating the use of language as a diagnost

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f53b6cf110db709028a488e6fe8f6f3c
https://hdl.handle.net/11370/f0f54b51-57dd-49ab-aa6f-37576256b295