Zobrazeno 1 - 10
of 45
pro vyhledávání: '"A E, Sloboda"'
Antiinflammatory and antiarthritic properties of a substituted quinoline carboxylic acid: CL 306,293
Autor:
A E, Sloboda, D, Powell, J F, Poletto, W C, Pickett, J J, Gibbons, D H, Bell, A L, Oronsky, S S, Kerwar
Publikováno v:
The Journal of rheumatology. 18(6)
CL 306,293, a substituted quinoline carboxylic acid at a daily oral dose between 1.5 and 3.0 mg/kg suppressed the inflammation and joint destruction (radiological criteria) associated with both developing and established adjuvant arthritis. When a we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6cdcb3bc7adb1a810a42d4eaaf3cdbe3
https://pubmed.ncbi.nlm.nih.gov/1895266
https://pubmed.ncbi.nlm.nih.gov/1895266
Autor:
Jay E. Birnbaum, Benjamin M. Sparano, David K. McClintock, Edward L. Tolman, Adolph E. Sloboda
Publikováno v:
Pharmacology. 25:27-38
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0317f65dd3581b8e20882da6a200fded
https://doi.org/10.1159/000137775
https://doi.org/10.1159/000137775
Publikováno v:
Journal of Medicinal Chemistry. 19:1404-1409
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3671a9c81ab8255c13bf177c1d48a7bc
https://doi.org/10.1021/jm00234a011
https://doi.org/10.1021/jm00234a011
Autor:
Arnold C. Osterberg, Adolph E. Sloboda
Publikováno v:
Inflammation. 1:415-438
Fenbufen [3-(4-biphenylylcarbonyl)propionic acid] was shown to be an orally and parenterally effective nonsteroidal antiinflammatory analgetic and antipyretic agent in animals. Like clinically useful drugs (aspirin, phenylbutazine and indomethacin) i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc8e1516192b1902a2cc23135322c290
https://doi.org/10.1007/bf00920340
https://doi.org/10.1007/bf00920340
Autor:
L. A. Harten, D. N. Ridge, John W. Hanifin, B. D. Johnson, G. Nicolau, D. E. Watts, Adolph E. Sloboda, J. Menschik
Publikováno v:
Journal of Medicinal Chemistry. 22:1385-1389
Benzoylacetonitrile and beta-aminocinnamonitrile are shown to possess potent antiinflammatory activity in the rat adjuvant arthritis model. In a series of phenyl-substituted analogues, only o-, m-, and p-fluorobenzoylacetonitrile and m- and p-fluoro-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75b66e71fa82de427b1c0dee525c23f2
https://doi.org/10.1021/jm00197a020
https://doi.org/10.1021/jm00197a020
Autor:
S. S. Kerwar, Adolph E. Sloboda
Publikováno v:
Agents and Actions. 12:216-220
The effects of fenbufen and sulindac, two novel antiinflammatory agents, on the developing and established lesion of type II collagen arthritis was investigated. Using paw diameter and radiology as parameters, these studies suggest that fenbufen is m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d3a766d7aa8c80629d031c45e126567
https://doi.org/10.1007/bf01965149
https://doi.org/10.1007/bf01965149
Autor:
Adolph E. Sloboda, S. S. Kerwar
Publikováno v:
Pharmacology. 25:12-20
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb947b01a35aa657c4a13683c92bfae9
https://doi.org/10.1159/000137773
https://doi.org/10.1159/000137773
Publikováno v:
Journal of Pharmaceutical Sciences. 66:466-476
One hundred analogs of fenbufen were prepared and tested using the carrageenan, polyarthritis, and UV erythema anti-inflammatory tests and the 2-phenyl-l,4-benzoquinone writhing and inflamed paw pressure analgesic tests. Only three retained the same
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cb2bc539db01aaa22d4b6de656f51ba
https://doi.org/10.1002/jps.2600660403
https://doi.org/10.1002/jps.2600660403
Autor:
A. E. Sloboda, Jane Landes
Publikováno v:
The Journal of Immunology. 104:185-194
Three different batches of rabbit anti-mouse thymocyte serum (RAMTS) were consistently more effective than simultaneously prepared antisera to mesenteric lymph nodes (RAMLS) in prolonging survival of ICR skin allografts on C3H mice. Antispleen sera (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eadc53cb0a687421e03bda776a9ae80a
https://doi.org/10.4049/jimmunol.104.1.185
https://doi.org/10.4049/jimmunol.104.1.185